>Tge ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------MKQNSKSAKVPKGDIKSLSGSL AVQFGHCNKNEKQSSPGGGGKILTCSMCKERFTRPRQLQLHMGKMHKNACEVCHKVFSRK HQLHYHRKSHFKDKSLICDICGYATYLKRFFESHRRRHFGDYTFKCDQCTSGFFSNAELL EHKVVHTGMRPYQCELCGKTFSKRRYLSTHMRYHDSNIYVCDICGN-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------SNKCDFCGKEFTRHKMLIHRRIHTGERPFVCSSCG EAFVSKGALTVHMVIHSDERPFSCKICHRAFKRAFELKDHNKIHTGEKNHICDICGYSCI QRTNLVNHRRRHLFEYKLSCDICSKGFYTKTELQEHRNGHTGEKPFQCDTC--------- ---------------EKAYKCEICNKTYSRKQVLLLHMKSHTGESQCICDICGKAVSSRD YLKIHVRTHTGEKPNVCDVCGKAFISKKYLKIHFRTHTGERPYTCEFCSKKFTQQSSLIV HRRSHIERIHVCHICKN------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------NKSHTGESQCVCSVCGKTVSNKYNLKVHVQTHTPDKQIVCDVCGKT FTQMSNLKIHYRIHT--------------------------------------------- ------------------------------------------------------------ -----EKSATSHKPVIHKCKICGREFNRKNGLTRHKAVHSAIRPYECPTCDKRFKRKCEL DLHKVTHTDAKQYACDICSLVCNRKGNLDSHRKRHFNAFTHFCSVCTKG----------- ------------------------------------------------------------ RRHAAEVVPQCICDICGKSLSSKEYLVLHRRIHTGEKPLSCDVCGKAFTQAKYLKVHQRT HTGERPFSCNICEKRFTQRSSLNAHM---------------------------------- -----------------------------------------------KSY---------- --HNDVRPFECSVCNKRFKRKYEVTVHKLTHTGDLKYSCDICNFVCNRKGNLEAHRKRHM NEFDYFCDICGKGFYNNFNLQGHKRVHIGLKPFLCDLCA-----------HKFV------ ------CDSCGKGFISRGNLKVHIKQHTG-GSPEYICDFCGKILSTRDS----------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------LKHHR------------------------------------ ---------------------------------------------RVHTGEKPFVCPVCG KAF--------------------------------------------------------- ------------------------------------------------------------ -SA---------------------------------------KKY--------------- ------------------LDVH---------------------------HR--------- --------------------THTGERPYSCELCG----KRYSMTKHNMKHNPSYKPDYKN KCAACGKGFVSRENLSM------------------------------------------- ------------------------------------------------------HMKRH- -----------------AGESPDYV---CDICGKVVTTRQSLR-LHRRIHTGEKPHVCPV CSKTF-SDISYLKVHHRTHTGERPFACDLCDKRF---------------TQSYSCDKCNY VSNRKGNLQTHQKKHLGYFSHFCDFCQKGFHSKFALVEHRNVHTGLKPFLCDICGMCFLR KDRLRAHNMKHRSEYKPCVKECDLCHK--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCGKSFPTKHGV KRHMFTTHNADYRPPPATCDICQKEFTYKKTLKRHMAQHTGILPEYVCDMCGKVV----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ RSGESLKAHRRTHTGEKPFSCKMCGKAFTS------------------------------ ------------------------------------------------------------ --SQYVTVHMRTHTGERPYI--------CQVCGKSFTQRP-------------------- ------------------------------------------------------------ ----------------------------------CLVGFRNKASLLEHKLVHTGLKPYLC DNCGESFTTNQRLKVHKLRHDADHRPELIQCGVCQRLFTFRNSLKRHMAQHTGNMPKFVC EVCGKVLTSRPSLRVHERTHSGEKPFGCKVCGKAFGGKTYLRV----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------HMRTHTGERPYSCDLCGKTFTQRS------------------ -C---------LWGH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TKSDVYKLKTHMEIHRAE KRYVCTVCGVAFVLKAYLNSHMLIHSDDRPHACEVCGKQFKRKQQLKLHLLIHKNERNHV CDICGSAFIQRTQLIYHCRRKHTKETTFHCDVCGKGFYNRNHFTDHTNLHTGYFPYKCEV CGKSYKVYSSFRYHKETHVTKSESGEMFKCETCLEIFSTKLILTLHKRRHAPKRACRLCN KQLSSSESLKVHLRIHAGEKPCICDVCGKRFVSRPLLRIHQRTHTGVKPYSCNVCGKMFT QRCTLTVH--------------------RR-----YHT-------GETPYGCQVCPKAFV SKNLLKAHLKTHEKQI-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------NSSRYTTK DDTVDTQKYCSPSDGVKLISDRIGLSVSLRSGTGDVPNYNCGICGKVCVSKGHLKRHQVS HTDDRPYHCDICDRNYKRAFELRKHKEIHTGEMDHVCDICGYATFRKSNLLVHKKRHLND YKFKCDTCGKGYYSNTELQRHMTIHTGERPFQCDVCGRAYPYKSNLATHKKKHNPNYKNN LKYQCEFCGKTFLHNNSLRIHR-------------------------------------- ------------------------------------------------------------ ------KYHL---------------GEN-------------------------------- ------------------------------------------------------------ ------QLM-------------------------HNLESHKKLHIQDFVDNPNFYCEFCG KSFLYSKSLRRHRDIHLGENKFECDICGKMLNSKEYMKVHLRIHKGDKPYVCDMCGKAFV TNKHLTIHRRTHTGEKLYTCGVCNKSFTQVGYLTIHKRSHTGERPYHCDACGKDFASKCQ LNSHRRTHLS-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------VKFDTVTFIKPEELSRQKLSSILQSKVLGPTIHPYRVGTNKIFKCTCCGKTYKT SSRLKEHALSHIPDKLFSCDMCDKKFKSKKRVHDHRKIHFKNFGCDICGYSSEKRVTIKL HKKMHYNVYKLYCGTCSKGFNSEKLLKKHEELHSGIKPFQCEECGKPFASKYNLQKHKRL HDPVFRNNPKYYCEFCGKGFLYTTSYTQVGYLTIHKRSHTGERPYHCDACGKDFASKCQL NSHQKSHAR--------------------------------------------------- ------------------------------------------------------------ -------------SKTLVETHRKMHYNEYKYYCSICSRGFNVVKLLKEHELLHTGIKPYQ CEECGRQFTSKYNLAKHKRLHEPGYKDNPKFFCEFCGRSFLYSTVLNKHRSGHLGENRFE CDVCGKVVNSKEYLKVHLRIHNGDKPYVCDICGKAFVTNKHLTVHRRTHTGEKLYTCNVC HKSYTQVGYLTIHKRSHTGERPYHCVVCGRDFAS-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------NGEKPFVCD VCGKAFVTNKHLTVHRRTHTGEKLYTCNVCNKSFTQ------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------CRYCGKGFRYRGKCEVHEKRHLGHKEVMCDICGKALSTVRELGLHMRRHTGEK PFVCSYCGKTFSRLNSLTLHVRVHTGERPYTCGECGKSFTQHSSYAIHKRHHTGERPYRC LICEKTFVSKSLLKYHM------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------RCKFCNKGFPGQSLCTRHEKHHLGVKEFI CDVCGKALSSAHAMSLHLRIHTGEKPFVCDFCGKMFGRSSALTMHLRVHTGERPYV---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------CNVCGKGFTQ PSTLTIHKRYHTGQKPYECKTCNKTF-------------------------CRFCDKGFP RQSSCVRHEKHHLGVREYACDVCGKALSSGPLLKLHMRIHTGEKPFACDVCGKSFGRVYA LTMHYRVHTGERPYGCSECGKRFTQHSSLTIHMRYHTGQKPY------------------ --------------------NEIKCEICGKIYKRRSTLQKHMFLHDGAHSHDCVVCQKSF RSEWHLKQHMKAHTREKNFKCDICGFRFGHNYTLENHKKRHSNS---------------- --------------------------------------------------------FRQQ SHRATHEKRHFGQKDHMCDICGRAVNSPTELKFHMRGHTGEKPYVCPYCDKAFIRLMALK IHLRVHTGERPHGCDHCDKRFTQRSSLTIHMRYHTGVRPYKCDTCSKTFVS--------- ------------------------------------------------------------ ---------RTLLITHIKTHPYK------------------NIHMREKKFKCDICGFQFG HKYSLENHKKRHLKDYRHRCDICDRGFYSNNEFLEHKKVHTGLTRVMLGRENTC-VC--- ------------------------------------------------------------ --------------RRHIEEVHFSVCNYCGKTLADKGSLKSHQRIHT------------- -----------------------------------------------------GFLYNSM LRSHLLSHTETRPYSCHVCGKKFKRKYEVRKHAKLHAFDRDYICDLCNYSTNCKHNFGIH RKRHFKQCEFRCDVCQKGCYSKGELQKHTAVHVEGKPYSCEVCGLSYSYKNNLSFHIKKH ETSYNPSKDYQCEICGKTFTNRSNLTSHVKFHLGKNKV---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VCDTCGKS--------------------------------------------- ---------------------------------------------LSSG----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------ES--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------LKTHMRIHTGEKPF-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------P--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------CS TCGK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------AFKD--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------KGYLRTH----------------------------------- 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------CLKRFVTRTLMKVHFKSH------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------- >Tps ----------------------------MSLKVS-------------------TEA---- -----------TSENFHTSVHSPA------------------------------------ ----------------------------------ERLYSCLGR----------------- -----------------------------GEAL---LAH--------------------- ---------------------------------WI------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------HCDL------------ ------------------------------------------------------------ --------------SKKQLM-----------------------------DH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------PLI-------- -----SPAKSRQKCVRKVKRRSPKKRRDSGKCEFCGKGFVQSKLEIHRRTHTGERPFMCS SCGITFLSNGKLKSHMNTHSEVRPHACTTCDRRFKRTKELSDHMKIHTGEKDFICNICGA AYIQKSNLVNHKKRHFGHFSFKCHVCDKGFYSKTELKEHSNIHLGVKPFVCEVCGKAYPY KHNLTTHKRKHDPKHTVSPNKHQCEVCGKVFAQ--------------------------- -----------RGSLTLHMRA---HTGQAIFVCNIIYDMYRKMESSAALANGKYLCNICG KICSSKTSFRYHLEIHSEVPKYKCDVCDKQFQTYPRLFNHRLIHRKSKDQVCDVCGYCTY YKAALDIHKMLHSQKFKLYCEICSKGFKSKCYYDDHMNTHTGNNPYICDICGKAFPCKSN LANHKIHHKPGYKPYSRLCEICGISVQRSSYESHQRRHNNEMYDCDICGKKITKKNSLIT HMRMHMNDKPHACD----------------------KTKAKRSSKSVKKRKKGADKEDLS GRLGMLVEPYEEALKWAITDDKMFSCSMCREKFPRARQLQLHMGKMHKNACEVCHKVFSR KHQLHYHRKSHFKDKSLICDICGYATYHKHLLDFHRKRHFGDYTFKCDQCTSGFFSNAEF LEHKVVHTGMRPHQCEVCGKTFSKRGYLSAHMRYHNDNLYVCDICGKSITKKNSLMTHLR KHMGDKRHFNTRRTSIVKIENVQFIDEDPPCDQNNITSMKQNSKSAKVPKGDIKSLSGSL AVEFGHCDKNEKQSSP-GGDKISTCSMCKERFTRPRQLQLHMGKMHKNACEVCHKVFSRK HQLHYHRKSHFENKSLICDICGYATYLKRFFESHRRRHFGEYAFKCDQCTSGFFSNAELL EHKAVHTGVRPYQCELCGKTFSKRRYLSTHMRYHDSNTYVCDICGKAFLDDYTRLGRNNS ITKEEKLKGKVKVIKLASESNFGKKIPSKRVALETLKSRKQERTFSCTGCSKKFVREHKL RCHMDNVHNKVHKCTVCGQTFEKAHQLSYHSVVHKKSKTEVCDICGYTAYYRCVIENHKR THFWGNEFSCDLCQRSFQGAYALMKHKVVHTDVKQYQCDLCGRLYVHKCNLTAHRKTHVS GYKRPMDGHQCEVCGRKFLAKNSLVKHVRSHVGQKLSLLSRCADLIQTDSANKLKRKSAH NSKEKRVNSVEKIIRNKKRLRSDLSSNKCDFCGKEFTRHKMLIHRRIHTGERPFVCSSCG EAFVSKGALTVHMVIHSDERPFSCKICHRAFKRAFELKDHNKIHTGEKNHICDICGYSCI QRTNLVNHRRRHLFEYKLSCDICSKGFYTKTELQEHRNGHTGEKPFQCDTCGVSYRYRYR LTVHKKKHEAGYIPPEKAYKCEICNKTYSRKQVLLLHMKSHTGESQCICDICGKAVSSRD YLKIHVRTHTGEKPNVCDVCGKAFISKKYLKIHFRTHTGERPYTCEFCSKKFTQQSSLIV HRRSHIERIHVCHICKNFVLPK------------------EISDKTVSCSSKAKPVKTLK IVVKKRQLVYNRGRGNRATKLSSCEHVHKCNTCGRGFKRKTTLDYHIMSHSDDRNFDCSI CKKKFKRDKDLRNHLTTHNREHMRYFCNSCDYVCNRKSNLELHR---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------DDRDMYCVDMEQESIFTS IASPKEKSATSRKPVIHKCTICGREFNRKNGLTRHKAVHSAIRPYECPTCDKRFKRKCEL DLHKVTHTDAKQYACDICSLVCNRKGNLDSHRKRHFNAFTHFCSVCTKGFYDSFTMKSHK RTHNKLKPFLCDLCGWKFTTGAQMAKHKLKHAPGYKSELFRCDDCDKCCLTKSNLMSHVR RRHAAEVVPQCICDICGKSLSSKEYLVLHRRIHTGEKPLSCDVCGKAFTQAKYLKVHQRT HTGERPFSCNVCEKRFTQRS--------------------------------KITPKTAT SSIDRISLAHVKEETIEELTVVSTLKCETYPLDLTHQIPTNKCDICNKTYHKKSDLDYHK ITHSDVRPFECSVCNKRFKRKYEVTVHKLTHTGDLKYSCDICNFVCNRKGNLEAHRKRHM NEFDHFCDICGKGFYNNFNLQGHKRVHIGLKPFLCDLCGLGFSYKAAMKKHKLSHNPGYK PKPKHECDICGKCFLSKSRLSVHIKRHYGEESPGFICDFCGKAVSSKDSLVTHQRIHTGE KPLSCDICGKAFSHVKYVKVHRRTHTGERPYSCDVCQKTFTQRNSLTAHKKSLKDIYLNC VRSSA---RCSQDVGASKLSVSQETEDVEDVVKFIVIPSKRGSSKLISIDNVVSLNSCQP FICDVCHKEYVSIDSLRRHMKRHREERPFTCNICRKCFKCKSELVAHQTVHNGNFKFRCE FCRYVSNRKTNLVLHRKRHLKQYSLSCDICRKEFYSKGDLREHISRHHSGIKPFLCDICG WGFISHYAMSQHKMKHAPDYKPAHRFVCDSCGKGFISRGN-------------------- ------------------------------------------------------------ ------------------------LKDPIFRHTHFWKCDMCDKEYSCESALRQHKKRHTE DRPFVCARCDKRFKRRCELDVHNSVHSGVFKYFCDLCNYVSNRKGNLDSHRKRHFNKFTH TCDTCLKGFHSKSALQEHSASHTGVKPFLCDVCGWGFLNRYSMTKHNMKHNPSYKPDYKN KCAACGKGFVSRENF--------------------------------------------- ------------------------------------------------------------ -SAFVGINNDSNGNIIGEGKHPDATALEKSISDKMIGK------GDERLQRDTKPFKCEM CYKEFDSTVKFMR-HQSRHNDLRPFSCTVCHMKFKANGALKNHAVVHSGTFSYSCDKCNY VSNRKGNLQTHQKKHLGYFSHFCDFCQKGFHSKFALVEHRNVHTGLKPFLCDICGMCFLR KDRLRAHNMKHRSEYKPCVKECDLCHKVFAHRNSLKRHISRHMSKTPEYVCDVCGKCVAT AASLRTHKRIHSGEKPFVCNFCGKPFSDNKYLSVHLRTHTGERPYTCTYCDKTFTQRSCL LGHIKLHHV-----------------------PNSRKTKDRRTIKASAKVKSRKTAVAKR LKKKLNPGRFDCVPCNKSYSLKRTLDRHKREHHEERVNACNTCGKRFKTRQTLKYHLAGH VAEFKYSCHLCNY----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------VRGDCLDNVSLPKDRPKGISCEHCGKSYVYKKSLVDHYKEHEKIYSCDVC GKNFDRSTRLKKHSVLHSKEFSYFCDQCNFVTHKKSYIYRHCKNHTNNFTHFCDVCQKGF RNNTSLLQHKIVHTGLKPHLCDICAKSFTTKHCLKLHKIRHHSDYRPKLVECGVCRRVFK R----------------------------------------RRNGGSE------LCSK-- --------NTDPHKTSLPR--NLTEKVSCELCGKSYFSKKRLDSHFRQH---------GY MCSCS--------------------------------ACGMKFKNRKSLKLHSAVHHKEF KYFCDHCNFVTYRKSYLRMHCKNHTSNFSHFCDVCRKGFRNKASLLEHELVHTGLKPYLC DSCGESFTTNQRLKVHKLRHDADHRPELIQCGVCQRLFTFRNSLKRHMAQHTGNVPKFVC EVCGKVLTSSPSLRVHERTHSGEKPFGCKVCGKAFGGKTYLR------------------ ---------------------------------------NEPCNQSLAPLVNSASLVNTR TSIDLVKPSEKLSARPLKATKNNFTETSLCKTVCCETCDKTFATKRLLIRHWTAHGDTYP HPCPVCSQKFKTVEHLKKHMGYHSGEKKFKCDMCGSSFSRQSYCKLHTMRHLKAFTLHCK QCGKGFHTRTELQGHVNVHHGGNKFVCQVCKQVYPHRYVLECHLRMHEPGYERKKRHQCE TCGKTFAYKSSLNLHSI--GSETTLPEGDGSSNNSIDSMNS-----------------KY VTNTNNIKTLGSKKSNKRNR-----DKNKTKNSNKLKTK--------------------- ----ASKKNSGRVPKIKTEPKMKLVFTGVEKGVQPSCKFCKITFSDVYKLKTHMEIHRGE KRYVCTVCGVAFVLKAYLNSHMLIHSDDRPHACEVCGKQFKRKQQLKLHLLIHKNERNHV CDICGSAFIQRTQLIYHCRRKHTKETTFHCDVCGKGFYNRNHFTDHTNLHTGYFPYKCEV CGKSYKVYSSFRYHKETHVTKSESGEMFKCETCLEIFSTKLILTLHKRRHAPKRACRLCN KQLSSSESLKVHLRIHAGEKPCICDVCGKRFVSRPLLRIHQRTHTGVKPYSCNVCGKTFT QRCTLTVH--------------------RR-----YHT-------GETPYGCQVCPKAFV SKNLLKAHLKTHEKQMSVNLGNRDYHVTQFYVVDLLSNSVASLSVEMTGHLKRFLFFAG- 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------- >Tdi MKE-VNPHLR-GGQSGKPFRKNHPPVHLTEIRTSISPSSVVELNTTSVLANYTTEAGFIQ DRFTLRGMCGVTTIDTHRTGHAASGCDPTVLVTVVDNGLAWLIEVALRVSHSSLMSSDKM KPRSGDWAGGKKTTTKPILSMVFLAVRRHGRPRDERLTTYLARVGAFTCMQALVDCERGE LRERLPADVTAIRTLARVAAPVTAQSIPAGECLPTPLAHKALLTGVHGGVNAQPLGDEPA STGVTEVRFDPQMTVLVVQKGLLRLKVPAARRAWIRLKVAVHALVDDEVLHENSYCPVCL ASCCASPILDRKDLGQDEQAKGRSPVCFLMCSDVVSPVLLPALGTH--FRLPLLPPGRRR RGAQNRFPPGIHARRHRRCLLFKLDILPWVHLLPVSLQCVFVGEEGPAR-VALVAVT-LV VEVEVLLLTEGFAAHVAKEPRRLFQSFGLLRAREEHRIVTPLFPLHPRRGARPVVLPIVP LAVFARRVALDLRVDVAVPRNEIRHLLHLDQHIRLTLDVRRHLGDVILHLHAAQGLNVYV VVLLGQGHLFLPTQINKLLLLLLFQQVLALFKMKLLLGFNIFRYHCSIEKPPPVHPTEIR TSTSPSSAAELNTTSALTNYATEAGEGGERQIFDKIATCLPVKVSQDDKLPKKICSDCVY RVENSYQFWNTTSNSEKQLLEWVVNDVKVDTKSNITMETEQLVLKEEAIDHDQTAADVAK SLSRVEAVLTEETGQPGGVSEEEEEEEDSDDGGGGGGGEDSNSEESGEEPPGKEEIESEE EEEEEEPYEELEPTTFVNVSLACDEAGPSGIQQTRQQTKQDSQASAASASATTENAEAPS TSAADPAASGLREYQVRKATAEDLSKQVNNELFEVATK-------RQEG----KLEALLK AQIGRPRFIYRRRPSDSSDKCSILLVETIKSFKYFEEVLKK---VRYIRPILPSMGWEFR GTEKRSPAKSRQKCVRKVKRRSPKKRRDSGKCEFCGKGFVQSKLEIHRRTHTGERPFMCS SCGITFLSNGKLKSHMNTHSEVRPHACTTCDRRFKRTKELSDHMKIHTGEKDFICNICGA AYIQKSNLVNHKKRHFGHFSFKCHVCDKGFYSKTELKEHSNIHLGVKPFVCEVCGKAYPY KHNLTTHKRKHDPKHTVSPNKHQCEVCGKVFAQ--------------------------- -----------RGSLTLHMRGD-LETDPGVDLWYSIYDMYRKMESSAALANGKYLCNICG KICSSKTSFRYHLEIHSEVPKYKCDVCDKQFQTYPRLFNHRLIHRKSKDQVCDVCGYCTY YKAALDIHKMLHSQKFKLYCEICSKGFKSKCYYDDHMNTHTGNNPYICDICGKAFPCKSN LANHKIHHKPGYKPYSRLCEICGISVQRSSYESHQRRHNNEMYDCDICGKKITKKNSLIT HMRMHMNDKPHACESIVKIETLVQFFGEDRPCEEKSKTKAKRSSKSVKKRKKGADKEDLS GRLGMLVEPYEEALKWAITDDKMFSCSMCREKFPRARQLQLHMGKMHKNACEVCHKVFSR KHQLHYHRKSHFKDKSLICDICGYATYHKHLLDFHRKRHFGDYTFKCDQCTSGFFSNAEF LEHKVVHTGMRPHQCEVCGKTFSKRGYLSAHMRYHNDNLYVCDICGKSITKKNSLMTHLR KHMGDKRH---------------------------------------------------- ---FGHCDKNEKQSSP-GGDKISTCSMCKERFTRPRQLQLHMGKMHKNACEVCHKVFSRK HQLHYHRKSHFENKSLICDICGYATYLKRFFESHRRRHFGEYAFKCDQCTSGFFSNAELL EHKAVHTGVRPYQCELCGKTFSKRRYLSTHMRYHDSNTYVCDICGKAFLDDYTRLGRNNS ITKEEKLKGKVKVIKLASESNFGKKIPSKRVALETLKSRKQERTFSCTGCSKKFVREHKL RCHMDNVHNKVHKCTVCGQTFEKAHQLSYHSVVHKKSKTEVCDICGYTAYYRCVIENHKR THFWGNEFSCDLCQRSFQGAYALMKHKVVHTDVKQYQCDLCGRLYVHKCNLTAHRKTHVS GYKRPMDGHQCEVCGRKFLAKNSLVKHVRSHVGQKLSLLSRCADLIQTDSANKLKRKSAH NSKEKRVNSVEKIIRNKKRLRSDLSSNKCDFCGKEFTRHKMLIHRRIHTGERPFVCSSCG EAFVSKGALTVHMVIHSDERPFSCKICHRAFKRAFELKDHNKIHTGEKNHICDICGYSCI QRTNLVNHRRRHLFEYKLSCDICSKGFYTKTELQEHRNGHTGEKPFQCDTCGVSYRYRYR LTVHKKKHEAGYIPPEKAYKCEICNKTYSRKQVLLLHMKSHTGESQCICDICGKAVSSRD YLKIHVRTHTGEKPNVCDVCGKAFISKKYLKIHFRTHTGERPYTCEFCSKKFTQQSSLIV HRRSHIERIHVCHICKKSFTTKAFLGMHLKEHN-------TISDKTVSCSSKAKPVKTLK IVVKKRQLVYNRGRGNRATKLSSCEHVHKCNTCGRGFKRKTTLDYHIMSHSDDRNFDCSI CKKKFKRDKDLRNHLTTHNREHMRYFCNSCDYVCNRKSNLELHRS--------------- ------------------------------STVEN----------------ILL------ ------------------PQS--------------------------------------- --------PKEEDMSVQQLSEEEEEEEEEEGDENMILPHMLEDDRDMYCVDMEQESIFTS IASPKEKSATSRKPVIHKCTICGREFNRKNGLTRHKAVHSAIRPYECPTCDKRFKRKCEL DLHKVTHTDAKQYACDICSLVCNRKGNLDSHRKRHFNAFTHFCSVCTKGFYDSFTMKSHK RTHNKLKPFLCDLCGWKFTTGAQMAKHKLKHAPGYKSELFRCDDCDKCCLTKSNLMSHVR RRHAAEVVPQCICDICGKSLSSKEYLVLHRRIHTGEKPLSCDVCGKAFTQAKYLKVHQRT HTGERPFSCNVCEKRFTQRSSLNAHMKSYHKCTKLLNLNYRAFHDDCFVPSKEITPKTAT SSIDRISLAHVKEETIEELTVVSTLKCETYPLDLTHQIPTNKCDICNKTYHKKSDLDYHK ITHSDVRPFECSVCNKRFKRKYEVTVHKLTHTGDLKYSCDICNFVCNRKGNLEAHRKRHM NEFDHFCDICGKGFYNNFNLQGHKRVHIGLKPFLCDLCGLGFSYKAAMKKHKLSHNPGYK PKPKHECDICGKCFLSKSRLSVHIKRHYGEESPGFICDFCGKAVSSKDSLVTHQRIHTGE KPLSCDICGKAFSHFIAELIRGSGHI----------LVTF-------ARKLSRNEIALLH IR------------------ISQETEDVEDVVKFIVIPSKRGSSKLISIDNVVSLNSCQP FICDVCHKEYVSIDSLRRHMKRHREERPFTCNICRKCFKCKSELVSHQTVHNGNFKFRCE FCRYVSNRKTNLVLHRKRHLKQYSLSCDICRKEFYSKGDLREHISRHHSGIKPFLCDICG WGFISHYAMSQHKMKHAPDYKPAHRFVCDSCGKGFISRGNLKNMTEIK--------LMNK FTVRILSL-------------------------------------------PY------- RSSNPAFLLKYVDVSYPGLSQEIQLKDPIFRHTHFWKCDMCDKEYSCESALRQHKKRHTE DRPFVCARCDKRFKRRCELDVHNSVHSGVFKYFCDLCNYVSNRKGNLDSHRKRHFNKFTH TCDTCLKGFHSKSALQEHSASHTGVKPFLCDVCGWGFLNRYSMTKHNMKHNPSYKPDYKN KCAACGKGFVSRENFYLENYDSLDGLVALS------------------------------ ------------------------------------------EIERINFPVTLWHKPKSQ SSAFVGINNDSNGNIIGEGKHPDATALEKSISDKMIGK------GDERLQHDTKPFKCEM CYKEFDSTVKFMR-HQSRHNDLRPFSCTVCHMKFKANGALKNHAVVHSGTFSYSCDKCNY VSNRKGNLQTHQKKHLGYFSHFCDFCQKGFHSKFALVEHRNVHTGLKPFLCDICGMCFLR KDRLRAHNMKHRSEYKPCVKECDLCHKVFVHRNSLKRHISRHMSKTPEYVCDVCGKCVAT AASLRTHKRIHSGEKPFVCNFCGKPFSDNKYLSVHLRTHTGERPYTCTYCDKTFTQRSCL LGHIKLHHVPKWTDDTRFSYRVLPHWMHDKNNPSSRKTKDRRTIKASAKVKSRKTAVAKR LKKKLNPGRFDCVPCNKSYSLKRTLDRHKREHHEERVNACNTCGKRFKTRQTLKYHLAGH VAEFKYSCHLCNYVTNRNNYLTVHIKNHDRFPVKLPQDASKMDSHLCETCGKSFPTKHGV KRHMFTTHNADYRPPPATCDICQKEFTYKKTLKRHMAQHTGILPEYVCDMCGKVVRSGES LKAHRRTHTGEKPFS----CKMCGKAFTSSQYVTVHMRTHTGERPYICQVCGKSFTQRPC L--------------------------------------------VDMSHFISLDSNPNK TSTSTSETTKVRGDCLDNVSLPKDRPKGISCEHCGKSYVYKKSLVDHYKEHEKIYSCDVC GKNFDRSTRLKKHSVLHSKEFSYFCDQCNFVTHKKSYIYRHCKNHTNNFTHFCDVCQKGF RNNTSLLQHKIVHTGLKPHLCDICAKSFTTKHCLKLHKIRHHSDYRPKLVECGVCRRVFK RRFTNEISFNNACLNFYQDIKPFV-NMCSNFNKTTTSILSERRNGGSE------LCSK-- --------NTDPHKTSLPR--NLTEKVSCELCGKSYFSKKRLDSHFRQH---------GY MCSCS--------------------------------ACGMKFKNRKSLKLHSAVHHKEF KYFCDHCNFVTYRKSYLRMHCKNHTSNFSHFCDVCRKGFRNKASLLEHELVHTGLKPYLC DSCGESFTTNQRLKVHKLRHDADHRPELIQCGVCQRLFTFRNSLKRHMAQHTGNVPKFVC EVCGKVLTSSPSLRVHERTHSGEKPFGCKVCGKAFGGKTYLRVHMRTHTGERPYSCDLCG KTFTQRSCLWGHTK----------------RSSSSSKFKNEPCNQSLAPLVNSASLVNTR TSIDLVKPSEKLSARPLKATKNNFTETSLCKTVCCETCDKTFATKRLLIRHWTAHGDTYP HPCPVCSQKFKTVEHLKKHMGYHSGEKKFKCDMCGSSFSRQSYCKLHTMRHLKAFTLHCK QCGKGFHTRTELQGHVNVHHGGNKFVCQVCKQVYPHRYVLECHLRMHEPGYERKKRHQCE TCGKTFAYKSSLNLHSI--GSETTLPEGDGSSNNSIDSMNS-----------------KY VTNTNNIKTLGSKKSNKRNR-----DKNKTKNSNKLKTK--------------------- ----ASKKNSGRVPKIKTEPKMKLVFTGVEKGVQPSCKFCKITFSDVYKLKTHMEIHRGE KRYVCTVCGVAFVLKAYLNSHMLIHSDDRPHACEVCGKQFKRKQQLKLHLLIHKNERNHV CDICGSAFIQRTQLIYHCRRKHTKETTFHCDVCGKGFYNRNHFTDHTNLHTGYFPYKCEV CGKSYKVYSSFRYHKETHVTKSESGEMFKCETCLEIFSTKLILTLHKRRHAPKRACRLCN KQLSSSESLKVHLRIHAGEKPCICDVCGKRFVSRPLLRIHQRTHTGVKPYSCNVCGKTFT QRCTLTVH--------------------RR-----YHT-------GETPYGCQVCPKAFV SKNLLKAHLKTHEKQMSVNLGNRDYHVTQFYVVDLLSNSVASLSVEMTGHLKRFLFFAAS IRHVILENLMESTNKNQTKIHLIVIEMKRSNSKVEIFQKPFKNYKKCSEKSQLSFESKRK YFGSLPQTKDRLVFSCDVCNKELKKKKYLNYHKVSHIDIRPCSCQICGKTFKHLYAVKMY ARIHEGVKDHCSVPHQKPLGHTHKKRHYKFNKFTCEFCDKGFISQFHYDEHKNLHTGNKQ FKCGIWGESCGVSSSWYYYRRSHAEGLDLNNNPRETYGKHFTNKRTLTIHVRTHSDKRDP GNPCADSLGQEGPWKSMCGLTRTRGTLAIHVQTHSDKRDPGNPCADSLGQEGPWQSMCGL TRTRGTLAIHVRTHSDKRDSGNPCADSLGQEGPWQSMCRLTRTRGTLAIHVRTHSDKRDP GNPCADSLGQEDFCLCGKALSGTESLKIHLRLHVGDMPFVCVSCGKAFVSREMLKTRSHT HTGGKPYSCTVCAKTFPQCLSLTIHLRYHSGERPYQHQLCSKTLLNIHLKIRNSSRYATK DDTTDTQKYLLPSDAVKAISNRIGLSVSLRSGTDDVPNYNCGICGKVCVSKGHLKRHQVS HTDARPYHCDICDRNYKRAFELRKHKEIHTGEMEHVCDICGYATFRKSNLLVHKKRHLND YKFKCDTCGKGYYSNTELQRHMTIHTGERPFQCDVCGRAYPYKSNLATHKKKHNPNYKNN LKYQCEFCGKTFLHNNSLRIHR-------------------------------------- ----------KFKIISVKTEGKSSSKGKPIRIPQDHNSLSKRKRSNKKDPWKCVSCLSSF PTFIRYKEHVMSHLGVAVAMVCDVCGENFSNPAGLIWHRRLHSASRGRTTNKPAPCEAPE PSNSSQKAPHPTARDPRRRARGLKQHTCDICGYSSKSKSFVAMHRKMHYNEYKFYCRICS KGYNSVKLLHDHEFLHTGVKAFQCDQCGKRFSSRHNLESHKKLHIQDFVNNPNFYCEFCG KSFLYSKSLRRHRDIHLGENKFECDICGKMLNSKEYMKVHLRIHKGDKPYVCDMCGKAFV TNKHLTIHRRTHTGEKLYTCGVCNKSFTQVGYLTIHKRSHTGERPYHCDVCGKDFASKCQ LNSHRKTHLNSLSLLREHAYCHVTERSFSCDLCNKKFKSKKRVHNHRQVHFKKHWCDICG YTSEKKHRSAHLGENRFECDLCGKVVNSKASMRTHLQVHSGEKPFVCDVCGKAFLTNKNL VVHRRTHTGEKLYSCGVCEKSFTQVGYLNIHKRLHTGERPYRCDACGKDFTSKCQLISHQ KIHTAGVMFDTVTFIKPEELSRQKLSSILQSKVLGPTIHPCGVGTNKIFRCTCCGKTYKT SSRLKEHALSHIPDKLFSCDMCDKKFKSKKRVHDHRKIHFKNFGCDICGYSSEKRVIIKL HKKMHYNVYKLYCGTCSKGFNSEKLLKKHEELHSGIKPFQCEECGKPFASKYNLQKHKRL HDPVFRNNPKYYCEFC-------------------------------------------- --------------------------------------------------VITLLKPKQP EPKRDLWKCTPCGQSFSLLSEFKSHIMSQHRRNSHPCDMCDLKFISPVRLAKHRKCHGVM IRYSCDICGYSGQSKTLVETHRKMHYNEYKYYCSICSRGFNVVKLLKEHELLHTGIKPYQ CEECGRQFTSKYNLAKHKRLHEPGYKDNPKFFCEFCGRSFLYSTVLNKHRSGHLGENRFE CDVCGKVVNSKEYLKVHLRIHNGDKPYVCDICGKAFVTNKHLTVHRRTHTGEKLYTCNVC HKSYTQVGYLTIHKRSHTGERPYHCVVCG----------ARSANKIFRQDWQYKLHLVSH VKEYTCNICKTKFVSEEALSLHKTRLHLNKRHLCSVCDFSHDSKFVLDLHQKAHFSKVKH VCSTCSKEFKTEQSLIDHNLLAHTGINPFKCDHCGKRYKSKYYLKFHQKLHEPGFKDNPK YYCEICGKGFLYISALNNHRENHLGSNKVVCAICDVPLASKRYMTVHMRIHSGEKPFVCD VCGKAFVTNKHLTVHRRTHTGEKLYTCNVCNKSFTQINF--------------------N SLTVKKLRVKSEQPRSKKNCKTQCDALKDNISRQVPSDSTIRCEICGKEYKLDINLSRHM AKHNPDNQIKCDVCDKTCPSGFQLKQHLKIHETAKLYSCDMCSYASHVQVNLHAHRKRHL HDYKARCDVCNRGFYSMCSYKLHQAVHKDEMPFSCDVCGKLYKFKHYLTDHLQTHKPDYE ETVLKFKCRYCGKGFRYRGKCEVHEKRHQGHKEVMCDICGKVLSTVRELGLHMRRHTGEK PYVCSYCGKLFSRLNSLTLHVRVHTGERPYTCDECGKSFTQHSSYAIHKRHHTGERPYCC LICQKTFVSKSLMKYHMKSHEEHKLKRINCILI----EKSKSSKVNRKASNSVSGPVKRK VSNKKSIKCKICGNEYKRNSTLQNHLLVHGQDSHECDLCNKPFKSEWHLKQHKKYHSKAR QYKCDMCGYETCIKGNLLCHKRKHLKHYIVKCDACNKGFYRTCDYQEHVKIHTGEKPHRC DKCGKSFPGKHRLANHKKTHEPDYEETVLRFRCKFCNKGFPGQSLCTRHEKHHLGVKEFI CDVCGKALSSAHAMSLHLRIHTGEKPFVCDFCGKMFGRSSALTMHLRVHTGERPYVCNVC EKGFTQPSTLTIHKRYHTGQKPYECKTCNKTFGFLLSRFTSDNIVSKSSEKSKRHSKNSL ISPKPLSSPIELMELEWGSAESPKWKCKICEKVFKHKCSLKNHMPLHNTEGSFKCDICHK LLKSDYQLTRHKKNHSQLKDYKCGICGYETCSNSKIESHKRRHLNEYKMKCELCNKGFYT SREFQEHSMLHTGERPHSCEVCGKSYPNKYRLTDHKKLHEPNYEEMFLRFKCRFCDKGFP RQSSCVRHEKHHLGVREYACDVCGKALSSGPLLKLHMRIHTGEKPFACDVCGKSFGRVYA LTMHYRVHTGERPYGCSVCGKRFTQHSSLTIHMRYHTGQKPYTSAKNWFVVVKSEDKSTC PQN----TRKTDPLGVNKLPNEIKCEICDKIYKRRSTLQRHMFLHDGAHSHDCVVCRKTF RSEWHLKQHTKAHTREKNFKCDICGFRFSHNYTLENHKKRHSNSYKHNCNLCGHGFHSNH EFLVHKKVHTGERPYCCEVCGKSYPNKYRLVDHKTIHRPDYEETFLRFKCKLCGKGFRQQ SHCATHEKRHLGQKDHMCDVCGRAVNSPTELKFHMRGHTGEKPYVCPYCDKAFIRLMALK IHLRVHTGERPHGCDHCDKRFTQRSSLTIHMRYHTGVRPYK-------LATDISGFVVEK SGEKPRNTKVSPKPVLVKIKPKRKKNDAAMKKSKHLNQKPKSDSSSLNTSKRVIKCKICG KMYKRNSTLRNHMVIHDNSHSYECDICRKELKSEWHLKQHVKSHMREKKFKCDICGFQFG HKYSLENHKKRHLKDYRHRCDICNRGFYSNNEFLEHKKVHTG------ERPHLCEICNKS YPNKYRLIYHKKMHEPDYEEMFLRFKCKFCEKGFRQRSNRNFRIRKHNSSRPHQYQCELC GKSFNQRSSLRLHSRRHAGEVHFLVCDYRGKTLADKGSLKSQQRTHTVDKLDWFKYGTTH GGYFMLESLLYRFTNTESNINLSKMIQRPPEEKITKKRKWDLIGPHKCSVCHKGFLYNSM LGSHLLSHTETRPYSCHVCGKKFKRKYEVRKHAKLHAFERDYVCDLCNYSTNCKHNFGVH RKRHFKQCEFRCDVCQKGCYSKGELQKHTAVHLEGKPYSCEVCGLSYSYKNNLSFHIRKH EPSYNPSKDYQCEICGKTFTNRSNLTSHVKFHLGKNKVVSKYVSPTGGFRCDICEKCYAR EGQLNKHKVTHSEFRPFHCSICPKTFKRKYELNTHVQIHNKEGRYSCDVCKYSTMKKSNL TLHRQRHFNQYNIKCEVCGKGYYTNYEMRLHKAVHIHGETKPFVCDVCDKQFYCEYNLNL HKKRHNSDQQSKEKFTCEHCGKKLHSRSELTRHSKYHSGNFQVVCDICGKCLSGTNVLQV HRRIHTGEKPFVCDVCGKAFSALSYLVLHKRSHTGEKPFPCGKCGKCFAQRSSRTIHMRY HTGERPYPCQICGRNKHTDLSERKRPAHNISHEKSRTKKLLQSSEFECPICGKVCEAKHR LKYHIMTHDESRPYKCDVCDKHFKNTWHVKKHKNITHLGVKNCVCKVCGYASFYRSQLKQ HEKCHGGTFKYKCELCEKSFPNKTAFQAHRITFHGEEPYKCAECDKTYSKKRTLDDHTKS HIPGYKPVMKHQCELCGKTFLRINELYVHNRRHSADKTHTCPLCDKPLSSPQSLKYHMRI HTGEKPLVCDTCGKSFRTSQLLRVHRRVHTGEKPYSCDLCSKSFSQCSTLTVHKRFHTGQ RPYICQVCNLSFVTRTKNDSMSVMGNSSYTLHKNEPNNLDQIHSRVSKQLPKTQKRNGAK KHPQPYECQTCGQVFTQRYKLNYHMVRHSNERQFLCVLCNKSFKRKYEKDNHERMSHLNE NKRFKCTFCNYMAYHLTKVKLHERIHTREFNIKCDKCGKGFPCLLTLRSHLITSHGAEPF TCTTCGKTYTKDSSLRAHAKCHSPGYTHEKKFQCDCCGKTFRTKMQLVVHGRSHTGERNF PCERCGKAFSSKHITDKLYYMDSKYVSSDLEEEIHSDNVRGIYTTDKETSSIIYLESKVD TRRRLNAKTKTDRKRSAPKVKQGRKRLLVKAKTQIKKNSSRVKVKLLSNSLDSLQALKRY PCDVCGRGFPLESVLADHMLEHDGALKESQEYPCPTCGRVYKQKSKLKTHMVRHSDVRNF PCDMCGKMFKRRFEVDKHKKLTHSNEKRHSCSLCGYKAYHLSQIKHHEKRHVGGFNYKCE DCDRSYPLQSELKAHRISCHNDEPYKCPTCLKSYGIKRNFDTHLKTHEPGYVAERKFQCE SCGNTYRHKSDLIKHREQNTCDLTFSRNSPPGSDGETVVPLEWQARIISQNNTLNNNKTD VGDPVLPLDLLQKNKCQLCRQTFLLESELAAHILDHAKDPGTSPRHPCPTCGQVFPKRFL MKRHLRRHDDVWQYKCDICSKFYKSKYSLDAHMKWSHSGETKNHSCSVCGYKAYHLSAIR QHEKIHTGVFDYTCGDCGRGFHTKTMLKSHRITAHDDEPFKCNYCGKIYRSKANRDEHVK IHDPDYVHVHQCELCGKTFHTKPELKKHLARHRGDEKYVCEECGKPFKSKTTLVNHTRIH SGDKPYVCLLCGKAFTTSFFLKTHVRIHTGEKPFSCEICSKSFSQKSSLTVHTRYHTGLR PYLCSVCNLGFVTRTLLNTHIKRHVTGIILNSYQDLHDTNLAWRPDLGSAWSLEPASPAV TQSRKADTKPLVSNDRGQFACQWCDKQCMNEYMLRRHIKGAHTTYKCQLCGKVYPQRRML TRHAKSHTELRPFSCEICARKFKQMFELRKHQKTHTGNKTFACHICDFSAYYKCVLREHV KKHSRDFGYHCDECDKGFHTPQQVDSHKITYHGAQPFQCNVCGKTYAVKNRLKVHKLVHN PSFVAERKHQCEACGKTYKRAGELARHMNLHTGENRYMCNDCGKCMTSKCSLRDHVKIHM GERPAVCEICGKAFVRHDYLKVHLRSHTGEKPYSCETCNKSFTQHSSLVIHRRYHTGHRP YDCSVCNKGFVSKTLLRTHQRGSKHINQGLPRYICRKFNTLHIICMPSQTPLKTTTSALD GETPGVSLKNYHCLPCNTSFVSLSELKKHNANNHNSINKCKSTQRPTDTRTRSSVKNQPG LNSSSSYHCLQCDKSFKNQYLFKRHNTSIHGCNTCNVCGKQFTKRHNFKRHMKRHVNTKH FACDYCKATFKEKGNLTRHERIHTGDKRYMCQFCDYSAYYIAEVNDHERKHIGNYRYSCE PCNKGFNSPQNLESHNISVHGAEPHKCELCEKSYTSKRSYKLHLLSHNPNYIPEQKFQCE TCGKTFTSAIVLRRHMVLHLAVKPFECDQCGKRLSYKRSLEDHIKTHTGERPAVCKVCSK AFARGYLATHMRSHTGAKPFTCTTCDKSFTQRSTLVIHQRSHTGLRPYQCPTCSKDFVTK TLLKYHQKTMTTALTSEFPGVTFKNYHCPSCNTSFLTLSELKKHERNHHSSLNKCKPTKP PTDTTSRSSIKKQSGINSSSSYPCVPCDKSFKNQYLFDRHNAAYHISNTCNICGKQFNKQ IDYKVHMKRFVDTQHFACDHCNAAFKDESSLTRHEQKHTDDKRYTCRFCDYFAYTITKIN DHERKHTGNHRYSCKPCKKGYTTLHNLESHNISVHSADPYKCSFCGKLYTCKYRYRRHLL EHKPNYIPENKFQCDTCGKTFTSAPVLKQHMVCHLAVKPYECNQCGKRVTSKSSLKNHTR THTGERPAVCKVCGKAFYRGYLTTHMRSHTGAKPYTCTTCDKSFTQRSTLVIHQRSHTGL RPYQCSTCSKDFVTKTLLKYHEKTMTTALTSETPGVDLKNYHCISCKLSFLSSFELKMHN VIYHNFRNRCNLTQRPTATTSRSSIKKPSRINPSDTYPCVPCDKSFKNQYLFNRHNAAYH SSNMCNVCGKQFNKQIDYKVHMKRFVETQHFACDHCNATFKDESNLIRHEQTHTDDKRLV CRFCNYSAYTITKINNHERKHTGNYRHHCKVCKKGYNSLQNLESHNISVHSAEPHKCSIC GKLYTSKYRYRRHLLEHKPNYIPENKFQCDTCGQTFKRAPILKKHMVCHLAVKPYECNQC GKRVTRKSSLKNHMRTHTGERPAVCNVCGKAFPSPYLSTHMRSHTGAKPFTCTTCDKSFT QRSTLQRLCHQDSFEISPEGAFKIDLLTIFIFVKNSGITFKNYHCPSCNTSFLTLSELKK HQRNHHSSLNKCKPTKPPTNTTSRSSIKKQSGINSSCSYHCVQCDKSFKNQYLFKRHNST IHSANTCNICGKQFTRRLNYKRHMKRHVNTKHFTCTHCIATFKDKGNLTRHERIHTGDKR YMCQFCDYSAYYITEVNDHERKHTGNYRYSCKSCNKGYNSPQDLESHNISIHGAEPHKCG FCGKSYTSKYRYKRHLLEHKPNYIPENKFQCDTCGKTFKMARILKRHMVCHLAVKPFECN QCGKRVSDKSSLEDHIRTHTGERPAVCNVCGKAFARGYLATHMRSHTGAKPFTCTTCDKS FTQRSTLVIHQRSHTGLRPYQCTTCSKDFVTKTLLKYHQKGSKHITQCVQRSICRKPNSL HIIRMSSQTPLKTTTSALTKNNPGSSFKNYRCLPCNTSFVGLSELKKHNASHHISVNKCS ICEKEFDKLHLFTQHLKRHIEPKHFTCQYCSVTFKDKCTLKRHEKKHTGEKGLECKFCEY TAHSRFLMNEHNRKHIGIYRYNCDICKKGFKSLQGLEGHNIRAHGAEPHKCELCGKLYAT KQNFRLHVQSHNPDFIEERKFQCENCGKTFKSGRDLKKHMVQHLTVKPYECNQCGKRVSN KVSLVDHIRTHTGERPAVCDICGKAFARHGYLAVHMRSHTGVRPFKCLTCGKCFTQRSPL VIHQRSHTGQRPYHCNVCEEKSFKPQIISNKGPLLGSREKSRVYNIKIINEAKLGCGSNS GNKELTCDKCGRKCVSKKRLKQHMVIHSENRPFSCEICFRKFKRSYEVNMHMKIHAQQKK YTCEICDYATTQKPYLNAHNKRHLREFKVTCDICGKGFYSEFDLKEHANAHTGDKSFQCD LCGKGYLYKNNLVAHKKTAHPAVQRDEKANCCEVCGKTFSYKKTTKPQRKIQKYVTKLSI KRHLINLKQEIPDYIGHEVDVLNEGTTTTTTGCNLLTCQICFMPFPSPHKLNVHLKSHHC KLKEDYSCNVCGKEFVSKKILRRHLVVHSKDRPYTCNICHKTFKRPYDITIHSKKHTGEN KLYCDICEYSTIYRSALATHRKRHFEEYKFRCEICGKGFFVNTWLQEHKNFHTGEKPFQC DLCGKAFPYTRYLVAHKKANHPDAQNPAKLNQCDTCGKTFAHRKSLTLHVKSHTGENVCL CDICGKALTNKEHLKFHRRIHTGEKPNVCDVCGKAFSKRCNLKLHERTHTGERPYTCDIC GKAFTQRSTLVIHKRYHTGQRPYLCHLWSNISCDSLDEKLIVDEYEILNLSDKTEAEPNA KEKTFQACNICGKVFSAKGIMSHLKKHSRPRDGPFDCSVCNRKFDCRSRFTYHLSTHTPT IALTCELCGKICFTKYSLRKHKRSHAIDRPHKCEVCKKSFKRPYELTNHKKTHSALRNFK CEVCDYVTTQRKYLKIHQKRHSNKFSFHCDVCGKGFDSNPQLEGHVNIHAGIKPHKCSIC DKAFSSKQYLVQHQESHGNSPYAQKRTIQCNMCGKIFRQRNSLSLHVKKSHRGNDTFLCD ICGKSLTDKYYLKLHRRIHAGEKPHVCQVCGKAFGKPDTLKSHERTHTGERPYTCDLCGK SFSQRSTLIIHLRYHMGETPYTCQRSKNWQFLNECTATNIKKEETSPQKNCVVVPSSGTK EDKSSEQCDLCGETLTARRMASHKKKHSLIGPHVCSVCGKMFNTESNLYFHVRTHTVSIA IKCGLCDTVCLSEKLLRSHMKTHTKERPYKCEVCDKTYKRSYELLKHKKIHTGVKNFKCN ICDYVTTYKAYLEIHKKRHMGDFKYHCEICGKGYYTNTALESHKNVHTGDKPFQCSICGK SFIYKYNMMAHKKQLHPDSDYGVASYVCLICDKSFAYKKSLLLHNAVHSGENQSISVNTR LRKRRTIIQTDQNNTSSNTSGLSKRLAGGVDRKEPKQSCKRLQKTSVYHSCDVCGKVFNN LSTLSFHLRSHNTPELIKCEYCAKTFKKNKRLKSHMKTHTTDRPYKCELCNKTYKRSFEL TSHKRLHEGVKSFKCDMCEYATVYRAHLESHKKRHTGDFKYHCEICGKGYYTNTGLEGHK NAHKGERPYQCAVCGKSFLHKYNMLAHKKQLHPDSDQIVKTHDCNICQKSFNYRKTLLSH VARHMGQKSLCDICGKAFVNNTSLQSHRRMHTGERPFRCETCGKTFGKRAILRVHERTHT GEKPYSCEVCGKCFAQRPPLVIHKRYHTGFEISLLSRLSSETASGQTLKSDWSSSILSTR LGLKVMWSGVSLTEQQENSDGGSRNGSKQECQSCDKAFNNRTKLVRHLREHESKDKVCKI CGKTFFGHKKLRNHMRSHLKERPFVCDRCSRAYKTQFELNGHKKIHTAEKSHVCDVCGYA TIYKAYLKVHQKRHMRQFRFNCDICGKGYYTNCELQIHKNVHTGEKPFQCDACGKAYIHK HYLIAHQRSHHPELQDDMTPYSCEICGKVFAYKKTDTEDIIKRRWYSTNKILAGSVSVYK VAVKNRSQKLTGQYKCLFCVKTCISEGGLKNHIKTHFPDEHFNCNFCDKVFSAVNTLSRH MLQHTTDQPYSCDICNKAFRHEYALTNHKKYHAGIKEFVCDICNYASDRKASLKIHIKRH TREAHHPCNMCEKSFYTNSELKVHKSIHFGKTHRCEICDKSFTHKRNMLMHQQSHDPMKE VRIFPCEICGKTYRRKTRLAVHVMYAELFDKSDSTSWNTQDSCRGKNKEGEELIRRFKLP AIVVERQTISQAKSCNLCAKSCKSEAGLKIHKKTHLSKKEFHCEFCGKVFAAVNLLSRHL ACHMTDRPFSCDICQKSFKRKQCLVDHKKFHSGVKAFVCDICSYATSHKASLEVHIKRHT CEAHFPCDTCSKSFYTNSELRTHKNTHIGKMHKCEFCERIFIHKKNMLSHQKTHDPAREI KKYPCEICGKIYRRKHRLTVHIRSHSGEQKFICDVCGKCVTSNVSLKTHHRLHTGEKPFV CDVCGKAFISTNYLLIHKRSHSGVKPHTCKQCGKSFTQRSTLVVHMRYHTGQRPYECLLC DKRFCKSTLPLRMLHSKPTNEETGDKGNLLGSKANANPHLVKGTDIFQCQTCGVAFLTEE EVVDHVQVVHFPCKYCAKVFTHFFHLKRHLPVHMKERPYKCDRCGKTYKRSFELSKHIRL HKEKKENIKRYKCDFCDFATEYKPSIDVHKKRHFNDFRFKCDLCDKGFYYNCQYQQHKAT HNGDVYPCKICEKRFPLQKKLDAHARIHDPEHRQERVTCGICGRSYQFKTTYMKHMRTHT DSESQTFMCDVCGKRVMSRVSLRHHRRLHTGERPFVCDTCGKPFNSSGILRVHKRSHTGE KPYSCENCGKSFTQRSTLVVHMRYHTGERPYECHLCTKSFEFISESEIPPLGKTRKKCKQ NTPCSFCGKSFKTKAGLKIHMKTHVSNKALICKSCDKVFTAVSLLVKHMASHTTDRPFPC DLCRKTFKRKHELVSHKKQHEGVKDFVCDICSYATGHKASLAVHIKRHTCEAQFPCNVCN RSFYTNSQLQNHINTHYGKKHQCEFCGKSFIHKYNMLIHQKSHDPSRDVRKFPCEICGKT YQRRNKLMMHIRLCTSPESPRAIKGGQPLIEGPGKKSETLECDTCGKRCKSKANLNLHSR VHDPSKHHKCKTCDKIFLDKHHLARHTATHSKERPYACDVCDKTYKCPFRLSSHKKGHCE KKKPHVCDICDYSTIYRYYLEIHKKRHASDFTFKCDLCGKGYYTATDLKRHRMIHDGSKH TCDVCGKEFTMDKNLKDHMRIHKSNRRRFNCALCGKSYFYTSQLNVHNCTKGEAVRYVCD VCGKTLTSASSLQSHRRLHTGEKPFMCDICLKSFNTATYLRIHKRSHTGEKPHVCGQCGK SFTQRSTLVVHYRYHSGERPFGWMTGNYGDLTEQLRNISPDVSSDHQSLPKHSRKSLVKD PQELTVTCKTAERKGSNYFKDPIINQNSDPSKMTTRNQPNSVRVKKPHGTKGPLICDTCG KLFPSVKRLNMHRKIHTDIRYTCDICLKTYKSISMFYTHKKFHKSLKTYDCDVCDYRTPW KGNMNNHRRRHFGETKVTCDMCDKGFYNKCDLEEHKNIHTGNKPFKCDICESPFWSKRSL WDHKKAQHNSNLKEFKCTQCGKSFVFKSRLNRHLEAHRGKRFMCDVCGKSVTSDQSLRAH KTIHTDEKKFLCDIQSSTDFQTMCTGTMDIETITIKSETSPFNEPTDMDEDNLNSYSTGV PKFSKTSINNLKVLTNPMIKVSQSKSSTTTLPNSFPPSEKIKPNLPTCGICNKFFSTYLA LNKHNNSHDRCAPPTTSQNSLPSEKIKPNLPTCEICNKFFTTYRALKKHNNTHDRCAPPT TSQNSPPSEQIKPNLPSCEPCNKFFSGYRALKEHNKTHGYMKSCDVCSKTFKFACQLKLH VQIHDKARPKLFCNLCSFSTLRKDSLITHRRTHMIENLYVCDICRKGFHRIGYLVKHLKV HAGKEPLKCEICGLTFLLKNKLSYHRKTVHKKSTKILCAHCDKECANQSEWRQHMRSHRC PDEHKTIQLEVLFFSKTSIHNVKVLTNPIIKVSQTGSSIHTTTTLPNSSPARKIKPKCPY SEVSNNIFTTKRVSCDVCFKSFRYASRLKLHMQTHSKERPKLFCDLCSFSTLRRDSLSKH RKRHVNENLYVCDICKRSFRERSDLVEHLKVHAGKEPFKCDICGLSFLLGSKLSYHRKTF HSNSGKISCAHCDKEFVHHFEWKMHMQGHKKEKLYTCDYCGRTFTTKNVLKIHIAVHMNI KSFSCKFCSLSFNTGQLLKLHTYLHMAKKPYMCKKCGQTFIQHSAYEAHIQPSTDFETTC TGTIDIETITIKSETSPFNEPTDMDINEEDNLNSYSTDKCFITKRALMEHKNAHRRYVIL YNFCSKSFRYPSKLRLHMQINDNTQHKLFCDQYSFSALRKDSLIKRRKRIFMFAIFVKEV SAKEEPFQCDICGLSFLLGSKLSYHRKTIHSNLEKNLIGRYIFEGIRNKSFKLVTTALHT YLHKTEKLYMCRKCGQTFIQHSAFETHVNYHTRKRPYICHICSKGLAKQLYLLKFLKSPS GNQTQPDESKENKKTEKKPVSIKYGQNKRHKGERNYLCHLCGKKFHEKQTLLLHGRVHTD VVIRSYPTRAHEYKEDRSV >Tbi ---------------------------MTSSAISL------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YIR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------RCRV------------ ------------------------------------------------------------ -------------TSAK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----SPAKSRQKCVRKVKRRSSKKRRDSGKCEFCGKGFVQSKLEIHRRTHTGERPFMCS SCGITFLSNGKLKSHMNTHSEVRPHACTTCDRRFKRTKELSDHVKIHTGEKDYICNICGA AYIQKSNLVNHKKRHFGQFSFKCHVCDKGFYSKTELKEHSNIHLGVKPFVCEVCGKAYPY KHNLTTHKRKHDPKHTVLPNKHQCEVCGK------------------------------- ------------GKVSNTNQGGGLDTDPGVDLWYSIYDMYRKMESSAALANGKYLCNICG KICSSKTSFRYHLEIHSEVPKYKCDVCDKQFQTYPRLFNHRLIHRKSKDQVCDVCGYCTY YKAALDIHKMLHSQKFKLYCEICSKGFKSKCYYDDHMNTHTGNNPYICDICGKAFPCKSN LANHKIHHKPGYKPYSRLCEICGISVQRSSYESHQRRHNNEMYDCDICGKKITKKNSLIT HMR--------------------------------------------------------- ----MLVEPYEEAVKWAITDDKMFSCSMCREKFPRARQLQLHMGKMHKNACEVCHKVFSR KHQLHYHRKSHFKDKSLICDICGYATYHKHLLDFHRKRHFGDYTFKCDQCTSGFFSNAEF LEHKVVHTGMRPHQCEVC------------------------------------------ ---------------------------DP---QNNITSMKQNSKSPKVPKGDIKSLSGSL AVEFRHCNTNENQSSP-GGGKILTCSMCKERFTRPRQLQLHMGKMHKNACEVCHKVFSRK HQLHYHRKSHFKDKSLICDICGYATYLKRFFESHRRRHFGDYTFKCDQCTSGFFSNAELL EHKVVHAGLRPYQCELCGKTFSKRRYLSTHMRYHDSNIYVCDICGK-----------NNS TTKEERLRGSVKVINLASESNFGKKIPSKRVASETVKSRKQERTFSCTGCSKKFVREHKL RCHMDNVHNKVHKCTVCGQTFEKAHQLSYHSVVHKKSKTEVCDICGYTAYYRCVIENHKR THFWGNEFSCDLCQRSFQGAYALMKHKVVHTDVKQYQCDLCGRLYVHKCNLTAHRKTHIS GYKRPTDGHQCEVCGRKFLAKNSLVKH------------------------------SAY NSKEKRVNNIEKRIRNEKRLRSDSSSNKCDFCGKEFTRHKMLIHRRIHTGERPFVCSSCG EAFVSKGALTVHMVIHSDERPFSCKICHRAFKRAFELKDHNKIHTGEKNHICDICGYSCI QRTNLVNHRRRHLFEYKLSCDICSKGFYTKTELQEHRNGHTGEKPFQCDTCGVSYRYRYR LTVHKKKHEAGYIPPEKAYKCEICNKTYSRKQVLLLHMKSHTGESQCICDICGKAVSSRD YLKIHVRTHTGEKPNVCDVCGKAFISKKYLKIHFRTHTGERPYTCEFCSKKFTQQSSLIV HRRSHIERIHVCHICKKSFTTKAFLGMHLKEHN-------T------------------- ----KGQLMYKRGRGNCAIKLSSCEDVHKCNTCGRGFKRKTTLDYHIMSHSDDRNFDCSI CKKKFKRDKDLRKHLTTHNREHMRYFCNSCDYVCNRKSNLELHRVRRHSKEFSFFCDICG KGFCSDSQLRYHRSNKSHTGESQCVCSVCGKTVSNKYNLKVHVQTHTPDKQIVCDVCGKT FTQMSNLKIHYRIHTGERPYSCE------------------------------------- -------LPKEEDMSIQQLSEEEEE-------ENMILPHMLEDDSDMYRVDMEQESIFTS IASPKEKSAMSHKPVIHKCKICGREFNRKNGLTRHKAVHSAIRPYECPTCDKRFKRKCEL DLHKVTHTDAKQYACDICSLVCNRKGNLDSHRKRHFNAFTHFCSVCTKGFYDSFTMKSHK RTHNKLKPFLCDLCGWKFTTGAQMAKHKLKHAPGYKSELFRCDDCDKCCLTKSNLMSHVR RRHAAEVVPQCICDICGKSLSSKE------------------------------------ -------------------------------CTKLLNLNNRAFHDDCFVPSKEITPKTAK SSIDHISLVHVKEETIEKLTTDSTLKCETYLPDLLPQISTNKCDICNKTYHKKSDLDYHK ITHSDVRPFECSVCNKRFKRKYEVTVHKLTHTGDLKYSCDICNFVCNRKGNLEAHRKRHM NEFDHFCDICGKGFYNNFNLQGHKRVHIGLKPFLCDLCGLGFSYKAAMKKHKLSHNPGYK PKPKHECDICGKCFLSKSRLSVHIKRHYGEASPGSSADCSG------------------- ------------------------------------------------------------ ---------ISQEIGASKLSVSQET----DIVKFLLIPNKRDSSKLISVDNVVSLNSCQS LICDVCHKEYVSIDSLRRHMKRHREDRPFTCNVCTKCFKCKSELVAHQTVHNGNFKFHCE FCRYVSNRKTNLVLHRKRHLKQYSLSCDICRKEFYSKGDLREHISRHHSGIKPFLCDICG WGFISHYAMTQHKMKHEPDYKPAHK----------------------------------- ------------------------------------------------------------ -SSNPAILLKYTAVSYPGLSQEIQLKDPIFRHTNVWKCDICNKEYSCESALHQHTKRHIE DRPFMCAKCDKRFKRQCELDVHNSVHSGVFKYFCDLCNYVSNRKGNLDSHRKRHFNKFTH SCDTCLKGFHSKSALQEHSASHTGVKPFLCDICGWGFSNRYSMTKHNMKHNPSYKPDYKN KCAACGKGF--------------------------------------------------- ------------------------------------------------------------ ----------------------------KSISGEMVGRRHATSFSNEHLERDTKPFKCET CYKEFDSSIKFMR-HQSRHNDLRLFSCTVCHMKFKTNGALKNHAVVHSGMFSYSCDKCNY VSNRKGNLQTHQKKHLGYFSHFCDFCQKGFHSKFALVEHRNVHTGLKPFLCDICGMCFLR KDRLRAHNMKHRSEYKPCVKECDLCHKVFAHRNSLKRHIT-------------------- ------------------------------------------------------------ ------------------------------------------------KVKSRKSANAKR PKKKLNPGKFDCVPCNKSYSLKRTLDRHKREHHEERVNACNTCGKRFKTRQTLKYHLAGH VAEFKYSCHLCNYVTNRNNYLTVHIKNHDRFPIKLPQDASKMDSHLCETCGKSFPTKHGV KRHMFTTHNADYRPPPATCDICQKEFTYKKTLKRHMAQHTGILPEYVCDMCGKVV----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------RPKGISCEHCGKSYVYKKSLVDHYKEHEKIYSCDVC GKSFDRSTRLKKHSVLHSKEFSYFCDQCNFVTHKKSYIYRHCKNHANNFTHFCDVCQKGF RNNTSLLQHKIVHTGLKPHLCDICAKSFTTKHCLKLHKIRHHSDYQPKLVECGVCHRVFK RRY----SLKQHMAQHTGDASKFVCDVCGKVVSTASYLRVHKRAHSGEKPFVCNVCDKAF SDSKYLRVHMRTHTGERPYMCNLCEKVSCELCGKSYFSKKRLESHFRQH---------GY VCSCN--------------------------------VCGMNFKNRKSLKLHSAVHHKEF KYFCDHCNFVTYRKSYLRMHCKNHENNFSHFCDVCRKGFRNKASLLEHKLVHTGLKPYLC DNCGESFTTNQRLKVHKLRHDADHRPELIQCGVCQRLFTFRNSLKRHMAQHTGNMPKFVC EVCGKVLTSRPSLRVHERTHSGEKPFGCKVCGKAFGGKTYLR------------------ ------------------------------------------------------------ ----------------------------------------TFASKHLLIRHRIAHGDTYP HPCPVCSQKFKTVEHLKKHMECHLGEKKFKCDMCDSTFSRQSYCKLHRMRHLKAFTLHCK HCGKGFHTRTELQGHVNVHHGGNMFVCHVCKRVYPHRYVLECHLRMHEPGYELKKRHQCE TCGKTFTYKNSLNLHT-------------------------------------------- ------------------------------------------------------------ -----SKKNSGRVPKIKTEPKMKLVFREVEKGVQPSCKFCKITFSDVYKLKTHMEIHRGE KRYVCTVCGVAFVLKAYLNSHMLIHSDDRPHACEVCGKQFKRKQQLKLHLLIHKNERNHV CDICGSAFIQRTQLIYHCRRKHTKETTFHCDVCGKGFYNRNHFTDHTNLHTGYFPYKCEV CGKSYKVYSSFRYHKETHVTKSESGEMFKCETCLEIFSTKLILTLHKRRHAPKRACRLCN KQLSSSESLKVHLRIHAGEKPCICDVCGKRFVSRPLLRIHQRTHTG-RNLNCHL-----N QRESILVHCLKLKTNWFSDVMFVTKNSKRRNLRQSFQTQICGEDEGVKDHVCDICSAAFL SKN----HLDTHKK---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------RHYKFHKFTCEFCDKGFI----------------- ----------------------------------------------ITMSTRTY------ ------------------------------------------------------------ ---------------------------------------IQETSRSIAGYV--------- ------------------------------------------------------------ ------VSCTV-----------------------------------------NSSRYTTK DDTADTQNYCSPSDGVKVISDRIGLSVSLRSGTGDVPNYNCGICGKVCVSKGHLKRHQVS HTDDRPYHCDICDRNYKRAFELRKHKEIHTGEMEHVCDICGYATFRKSNLLVHKKRHLND YKFKCDTCGKGYYSNTELQRHMTIHTGERPFQCDVCGRAYPYKSNLATHKKKHNPNYKNN LKYQCEFCGKTFLHNNSLRIHRNILLTLCNQHKILLHEFCFIRDISSYTRPHTLLLFCKW ERKISRYAVKRFKIISVKTEGKASSKGKPIRIPQDRNSLSKRKRSNRKEPLKCVSCPSSF TTFIRYKEHVMSHSSGAVAMVCDVCGENFSNPAGLIWHRRLHSASRGRTTKKPTPCEAPE PSNSSQRAPHPTVIGPRRRAIGLKRHTCDICGYSSKSKSFVAMHRKMHYNEYKFYCRICS KGYNSVKLLHDHEFLHTGVKAFQCDQCGKRFSSRHNLESHKKLHIQDFVNNPNFYCEFCG KSFLYSKSLRRHRDIHLGENKFECDICGKMLNSKEYMKVHLRIHKGDKPYVCDMCGKAFV TNKHLTIHRRTHTGEKLYTCGVCNKSFTQVGYLTIHKRSHTGERPYHCDVCGKDFASKCQ LNSHRRTHLS----VKEHAYCHVTERSFSCDLCNKKFKSKKRVHNHRQVHFKKHWCDICG YTSEK------------------------------------------------------- -------------------KSFTQVGYLNIHKRSHTGERPYRCDACGKDFASKCQLNSHQ KMH-AGVMFDTVTFIKPEELSRQKLSSILQSKVLGPTIHPYRVGTNKIFRCTCCGKTYKT SSRLKEHALSHIPDKLFPCDMCDKKFKSKKRVHDHRKIHFKNFGCDICGYSSEKRVIIKL HKKMHYNVYKLYCGTCSKGFNSEKLLKKHEELHSGIKPFQCEECGKPFASKYNLQKHKRL HDPVFRNNPKYYCEFCGKGFLYTTSYTQVGYLTIHKRSHTGERPYHCDACGKDFASKCQL NSHQKSHARVHQRRTVQKPKFVRIAPKPAPRPAPRPAPRPAPRPAPRLNQVVTLLKPKQP EPKRDLWKCTPCGQSFALLSEFKSHIMSQHRRNSHPCDMCDLKFISPVRLAKHRKCHGVM IRYSCDICGYSGQSKTLVETHRKMHYNEYKYYCSICSRGFNVVKLLKEHELLHTGIKPYQ CEECGRQFTSKYNLAKHKRLHEPGYKDNPKFFCEFCGRSFLYSTVLNKHRSGHLGENRFE CDVCGKVVNSKEYLKVHLRIHNGDKPYVCDICGKAFVTNKHLTVHRRTHTGEKLYTCNVC HKSYTQVGYLTIHKRSHTGERPYHCVICGRDFASKIQWRCKVCNKIFRQDWQYKLHLVSH VKEYTCNICKTKFVSEEALSLHKTRLHLNKKNVCSVCDFSHDSKFVLDLHQKAHFSKVKH VCSTCSKEFKTEQSLIDHDLLAHTGINPFRCDHCGKRYKSKYYLKFHQKLHEPGFKDNPK YYCEICGKGFLYKSALNNHRENHLGSNKVVCTICDVPLASKKYMTVHMRIHSGEKPFVCD VCGKAFVTNKHLTVHRRTHTGEKLYTCNVCNKSFTQVGYLTIHKRSHTGERPYRSKITIS SLTVNELRGKSVKLRSKKNCKAQCDALKDNIPNQVPSDSTIKCEICSKEYKLDINLSRHM EKHNPVNQIKCDVCDKTCPSGFQLKQHLKIHEMVKLYSCDMCSYSSHVQVNLHAHRKRHF NDYKARCDVCNRGFYSMCSYKLHQAVHKDEMPFSCDVCGKLYKFKHYLTDHLQTHKPDYE ETVLKFKCRYCGKGFRYRGKCEVHEKRHLGHKEVMCDICGKALSTVRELGLHMRRHTGEK PYVCSYCGKTFSRLNSLTLHVRVHTGERPYTCGECGKSFTQHSSYAIHKRHHTGERPYRC LICQKTFVSKSLLKYHMKSHEEHKSP--SSFFVEQSEEKSKRSKVKRKASNSISGPVKRK VSNKKSIKCKICGNEYKRNSTLQNHLLVHGQDSHECDLCNKPFKSEWHLKQHKKYHSKAR QYKCDMCGYETCIKGNLLCHKRKHLKHYIVKCDACNKGFYRTCDYQEHVKIHTGEKPHRC NKCGKSFPGKHRLANHKKTHEPDYEETVLRFRCKFCNKGFPGQSLCTRHEKHHLGVKE-- ------------------------------------------------------------ --------------------------------------FTSDNIVAKSPEKSKRHNKNFL ISPKSLSSPVELMELEWGSAENPKWKCKICEKVFKHKCSLKNHMPLHNTEGSFECDICHK LLKSDYQLTRHKKNHSQSKDYKCGICSYETCSNSKIESHKRRHMNEYKVKCELCNKGFYT SREFQEHTMLHTGERPHSCEVCGKSYPNKYRLADHKKLHEPNYEEMFLRFKCRFCDKGFP RQSSCVRHEKHHLGVREYACDVCGKALSSGPLLKLHMRIHTGEKPFACDVCGKSFGRVYA LTMHYRVHTGERPYGCSECGKRFTQHSSLTIHMRYHTGQKPYVC-------------STC TRSFVSKTLLTAHMKIKKLHNEIKCEICGKIYKRRSTLQKHMFLHDGAHSHYCVVCQKSF RSEWHLKQHMKAHTREKNFKCDICGFRFGHNYTLENHKKRHSNSYKHNCNLCGHGFHSNH EFLVHKKVHTGERPYCCEICGKSYPNKYRLVDHKMIHRPDYEETFLRFKCKLCGKGFRQQ SHCATHEKRHLGQKDHMCDICGRAVNSPTELKFHMRGHTGEKPYVCPYCDKAFIRLMALK IHLRVHTGERPHGCDHCDKRFTQRSSLTIHMRYHTGVRPYKCDTCLKTLATDISDFVVEK SGEKPKNTKETPKPVPLKIKPKRTKNDTATKKSKHLNKKLKSDSSRVSISKRVIKCKICG KMYKRNSTLRNHMVVHDNSHSYQCDICQKELKSEWHLKQHVKSHMREKKFKCDICGFQFG HKYSLENHKKRHLKDYRHRCDICDRGFYSNNEFLEHKKVHTG------ERPHLCEICNKS YPNKYRLIYHKKMHEPNYEEMFLRFKCKFCEKGFRQRS---------------------- ------------------------------------------------------------ ----------------------------------------------KCV----------- ----------------------------------------------------------LH EKRHLVQ--------------------HSSVHLKVKPFKCNQCNLSYSYKNNLNFHMRKH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ISSQ----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------PQQ------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ 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MSPIISKHIRVEGIGGTPNGDLNPNLPVTGNSVYCKGDD---------LDHAATEAG--- --------------------------------------------------STMLMSAD-- ------------------------------------------------------------ --------------------------IPAGK----------------------------- ------------------------------EGKYIN------------------------ ------------------------------CS-----FLFPSLVTRGGWEMAGIPLAREK S------PPN-SAYEGR-------DLI---------ITCLYLPGSGEDRGVSTVQGTALT TRPEVL---------VTKQNRR------------------------PSSG---------- ------------------------------------------------------------ ------------------------------------------------------------ SSSTPASG---------------------------------------------------- -------------RSDKQQG--------ADT----------------FIDKQQGADTLLD KQQGADTLLDKQQGADTLLDKQQDKQHGAD------------------------------ --------------TFLD-------------KQQGADTLLDKQQGADTLLDKQQGADT-- ----------LLDKQ-----QDDITLKSRPEMFQYDLQYLVKKGWRRWGLEGSKLVSTLH PQVQAPL---------ASNLTYIIIKVTLA-----KETLTKGLSVTTFKSIC-------- ----RSPAKSRQKCVRKVKRRSSKKRRDSGKCEFCGKGFVQSKLEIHRRTHTGERPFMCS SCGITFLSNGKLKSHMNTHSEVRPHACTTCDRRFKRTKELSDHVKIHTGEKDYICNICGA AYIQKSNLVNHKKRHFGQFSFKCHVCDKGFYSKTELKEHSNIHLGVKPFVCEVCGKAYPY KHNLTTHKRKHDPKHTVLPNKHQCEVCGKEKTKSGNLTRTNKNTSLKLSRKVKKSVKATR LPRLRRNDKEAKGKVSNTNQGGGLDTDPGVDLWYSIYDMYRKMESSAALANGKYLCNICG KICSSKTSFRYHLEIHSEVPKYKCDVCDKQFQTYPRLFNHRLIHRKSKDQVCDVCGYCTY YKAALDIHKMLHSQKFKLYCEICSKGFKSKCYYDDHMNTHTGNNPYICDICGKAFPCKSN LANHKIHHKPGYKPYSRLCEICGISVQRSSYESHQRRHNNEMYDCDICGKKITKKNSLIT HMRMHMNDKPHACESVVKIETLVQFFGEDRPCEEKSMTKAKRSSKSVKKGKEGADREDLS GRLGMLVEPYEEAVKWAITDDKMFSCSMCREKFPRARQLQLHMGKMHKNACEVCHKVFSR KHQLHYHRKSHFKDKSLICDICGYATYHKHLLDFHRKRHFGDYTFKCDQCTSGFFSNAEF LEHKVVHTGMRPHQCEVS------------------------------------------ ---------------IVKIENVQFFDEDP---QNNITSMKQNSKSPKVPKGDIKSLSGSL AVEFRHCNTNENQSSP-GGGKILTCSMCKERFTRPRQLQLHMGKMHKNACEVCHKVFSRK HQLHYHRKSHFKDKSLICDICGYATYLKRFFESHRRRHFGDYTFKCDQCTSGFFSNAELL EHKVVHAGLRPYQCELCGKTFSKRRYLSTHMRYHDSNIYVCDICGK-----------NNS TTKEERLRGSVKVINLASESNFGKKIPSKRVASETVKSRKQERTFSCTGCSKKFVREHKL RCHMDNVHNKVHKCTVCGQTFEKAHQLSYHSVVHKKSKTEVCDICGYTAYYRCVIENHKR THFWGNEFSCDLCQRSFQGAYALMKHKVVHTDVKQYQCDLCGRLYVHKCNLTAHRKTHIS GYKRPTDGHQCEVCGRKFLAKNSLVKHV------------RCADLIQTDSANKFKRKSAY NSKEKRVNNIEKRIRNEKRLRSDSSSNKCDFCGKEFTRHKMLIHRRIHTGERPFVCSSCG EAFVSKGALTVHMVIHSDERPFSCKICHRAFKRAFELKDHNKIHTGEKNHICDICGYSCI QRTNLVNHRRRHLFEYKLSCDICSKGFYTKTELQEHRNGHTGEKPFQCDTCGVSYRYRYR LTVHKKKHEAGYIPPEKAYKCEICNKTYSRKQVLLLHMKSHTGESQCICDICGKAVSSRD YLKIHVRTHTGEKPNVCDVCGKAFISKKYLKIHFRTHTGERPYTCEFCSKKFTQQSSLIV HRRSHIERIHVCHICKK--CPKEIVVNNIGSSNASIVLPKEISNKTVSCSSKAKSVKTLK IVVKKGQLMYKRGRGNCAIKLSSCEDVHKCNTCGRGFKRKTTLDYHIMSHSDDRNFDCSI CKKKFKRDKDLRKHLTTHNREHMRYFCNSCDYVCNRKSNLELHRVRRHSKEFSFFCDICG KGFCSDSQLRYHRSNKSHTGESQCVCSVCGKTVSNKYNLKVHVQTHTPDKQIVCDVCGKT FTQMSNLKIHYRIHTGERPYSCESLKLEKTLAPESLKEENILAMQSSKVEYMLVPQSSTV ENTLLPQLPKEEDMSIQQLSEEEEE-------ENMILPHMLEDDSDMYRVDMEQESIFTS IASPKEKSAMSHKPVIHKCKICGREFNRKNGLTRHKAVHSAIRPYECPTCDKRFKRKCEL DLHKVTHTDAKQYACDICSLVCNRKGNLDSHRKRHFNAFTHFCSVCTKGFYDSFTMKSHK RTHNKLKPFLCDLCGWKFTTGAQMAKHKLKHAPGYKSELFRCDDCDKCCLTKSNLMSHVR RRHAAEVVPQCICDICGKSLSSKE------------------------------------ -------------------------------CTKLLNLNNRAFHDDCFVPSKEITPKTAK SSIDHISLVHVKEETIEKLTTDSTLKCETYLPDLSPQISTNKCDICNKTYHKKSDLDYHK ITHSDVRPFECSVCNKRFKRKYEVTVHKLTHTGDLKYSCDICNFVCNRKGNLEAHRKRHM NEFDHFCDICGKGFYNNFNLQGHKRVHIGLKPFLCDLCGLGFSYKAAMKKHKLSHNPGYK PKPKHECDICGKCFLSKSRLSVHIKRHYGEASPG-------------------------- ------------------------------------------------------------ -----------------------------------------DSSKLISVDNVVSLNSCQS LICDVCHKEYVSIDSLRRHMKRHREDRPFMCNVCTKCFKCKSELVAHQTVHNGNFKFHCE FCRYVSNRKTNLVLHRKRHLKQYSLSCDICRKEFYSKGDLREHISRHHSGIKPFLCDICG WGFISHYAMTQHKMKHEPDYKPAHKFVCDS------------------------------ ------------------------------------------------------------ -SSNPAILLKYTAVSYPGLSQEIQLKDPIFRDTNVWKCDICNKEYSCESALHQHTKRHIE DRPFMCAKCDKRFKRQCELDVHNSVHSGVFKYFCDLCNYVSNRKGNLDSHRKRHFNKFTH SCDTCLKGFHSKSALQEHSARHTGVKPFLCDICGWGFSNRYSMTKHNMKHNPSYKPDYKN KCAACGKGFVSRENLSMHMKRH-----AGD------------------------------ ------------------------------------------EIEKINFPVTLWHKPKSQ SSAFVGINNDSNENIIGEGKDSDATAFEKSISVEMVGRRHATSFSNEHLERDTKPFKCET CYKEFDSSIKFMR-HQSRHNDLRLFSCTVCHMKFKTNGALKNHAVVHSGMFSYSCDKCNY VSNRKGNLQTHQKKHLGYFSHFCDFCQKGFHSKFALVEHRNVHTGLKPFLCDICGMCFLR KDRLRAHNMKHRSEYKPCVKECDLCHKVFAHRNSLKRHISRHMGKTPE------------ ------------------------------------------------------------ -----------WTDDTMFSYLVLPHWMHDKNNPRSRKTKGGRTIKASAKVKSRKSANAKR PKKKLNPGRFDCVPCNKSYSLKRTLDRHKREHHEERVNACNTCGKRFKTRQTLKYHLAGH VAEFKYSCHLCNYVTNRNNYLTVHIKNHDRFPIKLPQDASKMDSHLCETCGKSFPTKHGV KRHMFTTHNADYRPPPATCDICQKEFTYKKTLKRHMAQHTGILPEYVCDMCGKVVRA--- --------TFENPFSLLSRCKN-----------EVHFRN---KWP--------NFIQ--- ----------------------------------------------DMSHFISVDSNLNK --TSTSETTNVLEECLDNVSFPKDRPKGISCEHCGKSYVYKKSLVDHYKEHEKIYSCDVC GKSFDRSTRLKKHSVLHSKEFSYFCDQCNFVTHKKSYIYRHCKNHANNFTHFCDVCQKGF RNNTSLLQHKIVHTGLKPHLCDICAKSFTTKHCLKLHKIRHHSDYQPKLVECGVCHRVFK RRY----SLKQHMAQHTGDASKFVCDVCGKVVSTASYLRVHKRAHSGEKPFVCNVCDKAF SDSKYLRVHMRTHTGERPYM--------CNLCGKTFTQGSCLGTHTKKHHTLDLKRKNGG SAQCLKNTDPHKISLPRSLTEKLFFQKKTGKSLQTTWLCGMNFKNRKSLKLHSAVHHKEF KYFCDHCNFVTYRKSYLRMHCKNHENNFSHFCDVCRKGFRNKASLLEHKLVHTGLKPYLC DNCGESFTTNQRLKVHKLRHDADHRPELIQCGVCQRLFTFRNSLKRHMAQHTGNMPKFVC EVCGKVLTSRPSLRVHERTHSGEKPFGCKVCGKAFGGKTYLRVHMRTHTGERPYSCDLCG KTFTQRSCLWGHTKRSSLDAHKNVKTVMKLRSSSSSKFKNEPCNQSLAPLVSSASLVNTK TSSDLVKPLEKLSPRPLKGTKNNFT-----KTVCCETCDKTFASKRLLIRHRIAHGETYP HPCPVCSQKFKTVEHLKKHIECHLGEKKFKCDMCDSTFSRQSYCKLHRMRHLKAFTLHCK HCGKGFHTRTELQGHVNVHHGGNMFICHVCKRVYPHRYVLECHLRMHEPGYELKKRHQCE TCGKTFAYKNSLNLHT-------------------------------------------- ------------------------------------------------------------ -----SKKNSGRVPKIKTEPKMKLVFREVEKGVQPSCKFCKITFSDVYKLKTHMEIHRGE KRYVCTVCGVAFVLKAYLNSHMLIHSDDRPHACEVCGKQFKRKQQLKLHLLIHKNERNHV CDICGSAFIQRTQLIYHCRRKHTKETTFHCDVCGKGFYNRNHFTDHTNLHTGYFPYKCEV CGKSYKVYSSFRYHKETHVTKSESGEMFKCETCLEIFSTKLILTLHKRRHAPKRACRLCN KQLSSSESLKVHLRIHAGEKPCICDVCGKRFVSRPLLRIHQRTHTGVKPYSCNVCGKTFT QRCTLTVH--------------------RR-----YHT-------GETPYGCQFCPKAFV SKNLLKAHLKTHEKQMSI------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------MD LIKL--------------------------------------YTVFFIG----------- -----------------------------------IVLPKEISNKTVSCSSKAKSVKTLK IVVKKGQLMYKRGRGNCAIKLSSCEDVHKCNTCGRGFKRKTTLDYHIMSHSDDRNFDCSI CKKKFKRDKDLRKHLTTHNREHMRYFCNSCDYVCNRKSNLELHRVRRHSKEFSFFCDICG KGFCSDSQLRYHRSNKSHTGESQCVCSVCGKTVSNKYNLKVHVQTHTPDKQIVCDVCGKT FTQMSNLKIHYRIHT------------------ESLKEENILATQSSKVEYMLVPQSSTV ENTLLPQLPKEEDMSIQQLSEEEEE------DENMILPHMLEDDSDMYHVDMEQESIFTS IASPKEKSATSHKPVIHKCKICGREFNRKNGLTRHKAVHSAIRPYECPTCDKRFKRKCEL DLHKVTHTDAKQYACDICSLVCNRKGNLDSHRKRHFNAFTHFCSVCTKGFYDSFTMKSHK RTHNKLKPFLCDLCGWKFTTGAQMAKHKLKHAPGYKSELFRCDDCDKCCLTKSNLMSHVR RRHAAEVVPQCICDICGKSLSSKEYLVLHRRIHTGEKPLSCDVCGKAFTQAKYLKVHQRT HTGERPFSCNICEKRFTQRSSLNAHMKSYHKYTKLLNLNYRAFHDDCFVPSKEITPKTAK SSLDHISLTHVKEETIEKLTTDSTLKCETYPLDLSPQIPTNKCDICNKTYHKKSDLDYHK ITHSDVRPFECSVCNKRFKRKYEVTVHKLTHTGDLKYSCDICNFVCNRKGNLEAHRKRHM NEFDYFCDICGKGFYNNFNLQGHKRVHIGLKPFLCDLCGLGFSYKAAMKKHKLSHNPGYK PKPKHECDICGKCFLSKSRLSVHIKRHYGEASPGSLKD---------------------- -------------------------------------------------------IYLNC VRSSADCSRISQEIGASKLSVSQET----DIVKFLLIPNKRGSSKIISVDNVVSLSSCQS LICDVCHKEYVSIDSLRRHMKRHREERPFTCNVCTKCFKCKSELVAHQTVHNGNFKFHCE FCRYVSNRKTNLVLHRKRHLKQYSLSCDVCRKEFYSKGDLREHISRHHSGIKPFLCDICG WGFISHYAMTQHKMKHEPDYKPAHKFVCDSCGKGFISRGNLK--VHIKQHTGGSPEYICD FCGKVLSTRDSLKHHRRVHTGEKPFVCPVCGKAFSAKKYLDVHHRTHTGERPYSCELCGK RSSNPAILLKYAAVSYLGLSQEIQLKDPIFRDTNVWKCDICNKEYSCESALHQHTKRHIE DRPFMCAKCDKRFKRRCELDVHNSVHSGVFKYFCDLCNYVSNRKGNLDSHRKRHFNKFTH SCDTCLKGFHSKSALQEHSASHTGVKPFLCDICGWGFLNRYSMTKHNMKHNPSYKPDYKN KCAACGKGFVSRENLSTHMKRH-----AGESPDYVCDICGKVVTTRQSLRLHRRIHTGEK PHVCPVCSKTFSDISYLKVHHRTHTGERPFACDLCDKRFTQREIEKINFPVTLWHKPKSQ SSAFVGINNDSNGNIVGEGKDSGATALEKSISDKMIGRRHATSFSNEHLERDTKPFKCET CYKEFDSSIKFMR-HQSRHNDLRPFSCTVCHMKFKTNGALKNHAVVHSGMFSYSCDKCNY VSNRKGNLQTHQKKHLGYFSHFCDFCQKGFHSKFALVEHRNVHTGLKPFLCDICGMCFLR KDRLRAHNMKHRSEYKPCVKECDLCHKVFAHRNSLKRHISRHM----------------- ------------------------------------------------------------ -------------DDTMFSYLVLPHWMHDKNNPSSRKTKGRRTIKASAKVKSRKSANAKR PKKKLNPGRFDCVPCNKSYSLKRTLDRHKREHHEERVNACNTCGKRFKTRQTLKYHLAGH VAEFKYSCHLCNYVTNRNNYLTVHIKNHDRFPIKLPQDASKMDSHLCETCGKSFPTKHGV KRHMFTTHNADYRPPPATCDICQKEFTYKKTLKRHMAQHTGILPEYVCDMCGKVVRSGES LKAHRRTHTGEKPFS----CKMCGKAFTSSQYVTVHMRTHTGERPYICQVCGKSFTQRPC LVGHMKTHHSQKTLTLAVATFENPFFLLSRCKNDVHFRNKWPNFIQDVSHFISVDSNLNK --TSTSETTKVREECLDNVSFPKDRPKGISCEHCGKSYVYKKSLVDHYKEHEKIYSCDVC GKSFDRSTRLKKHSVLHSKEFSYFCDQCNFVTHKKSYIYRHCKNHAKNFTHFCDVCQKGF RNNTSLLQHKIVHTGLKPHLCDICAKSFTTKHCLKLHKIRHHSDYQPKLVECGVCHRVFK RRFTNEIPFNNAWLNFYQDIKPFV-NIYSNFNKTTTSILSERKNGGSA------QCLK-- --------NTDTHKISLPR--SLPEKVSCELCGKSYFSKKRLESHFRQH---------GY VCSCN--------------------------------VCGMNFKSRKSLKLHSAVHHKEF KYFCDHCNFVTYRKSYLRMHCKNHTNNFSHFCDVCRKGFRNKASLLEHKLVHTGLRPYLC DNCGESFTTNQRLKVHKLRHDADHRPELIQCGVCQRLFTFRNSLKRHMAQHTGNMPKFVC EVCGKVLTSRPSLRVHERTHTGEKPFGCKVCGKAFGGKTYLRVHMRTHTGERPYSCDLCG KTFTQRSCLWGHTKRSSLDAHKNVKTIMKLRSSSSSKFKNEPCNQSLAPLLCSASLVNTR TSTDLIKPLEKISPRPLKGTKNNFT-----KTVCCETCDKTFATKRLLIRHRIAHGDTYP HPCLVCSQKFKTVEHLKKHMECHLGENKFKCDMCDSTFSRQSYCKLHRMRHLKAFTLHCK HCGKGFHTRTELQGHVNVHHGGNKFVCHVCKRVYPHRYVLERHLRMHEPGYELKKRHQCE TCGKTFAYKSSLNSHSKRHAGHTFVCDVCGKCMTSRWSLVTHLRIHSGEKPLVCDVCGKS FTKSTGLKVHRRTHTGERPYGCDLCGKSFTQCSTMVIHKRYHSGLRPFECAECGRSFVSG TLLNTSKKNSGRVPRIKTEPKMKLVFKEAEKGVQPCCKFCKITFSDVYKLKTHMEIHRAE KRYVCTVCGVAFVLKAYLNSHMLIHSDDRPHACEVCGKQFKRKQQLKLHLLIHKNERNHV CDICGSAFIQRTQLIYHCRRKHTKETTFHCDVCGKGFYNRNHFTDHTNLHTGYFPYKCEV CGKSYKVYSSFRYHKETHVTKSESGEMFKCETCLEIFSTKLILTLHKRRHAPKRACRLCN KQLSSSESLKVHLRIHAGEKPCICDVCGKRFVSRPLLRIHQRTHTGVKPYSCNVCGKTFT QRCTLTVH--------------------RR-----YHT-------GETPYGCQVCPKAFV SKNLLKAHLKTHEKQINLNC-----HLNQ------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------RES------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------IFCSL-----PQ----------------------------------------TK DELV----------------------------------FRC-----------DLKYHKVS HIDIRPFSCQI----YGKAF---KHK---------------YAA---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------KMHASIHEGVKNHVCDICSEAFL SKNHL------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------DTHKKRH---YKFY---------------------------- -----------------------------KFTCEFYGKDF-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------ITMSTRTYTRE-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------TIR------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ 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