>Tge
MEKELTSVQSTMKRHHEEEAAQGVKPTQRPMVQKKGRVTAISHVLNSK--
--------------------------------HGSKVFFLELFTDTRDVV
HVASSLESQAVWLTQINIDSSYCFTHLQPRQIVFK---------------
----------------------------PKRNIILxxxxDTQHPLSAVPD
TQHPLSAVPDTQHPLSAVPDTQHPLSAVPDTQHPLSAVPDTQHPLSAVPN
TQHPLSAVPNTQHPLSAVPDTQHPLSAVPDTQHPLSAVPDTQHPLSAVPD
TQHPLSAVPDTQHPLSAVPDTQHPLSAVPDTQHPLSAVPDTQHPLxxxxD
TQHPLSAVPDTQHPLSAVPDTQHPLSAVPDTQHPLSAVPDTQHPANCQVF
FHRMEASSWFGKPVKYLSALKLKKAALSKSMIVTISFPMSNPTLKCQQGY
VTDVFRPLAMFQLDNKLNFCTAMMMKVSDVPQLCVGQHVIVYNVHCVSRD
LMMCARSRVSIVPHPEQYVPAGAPGREAEKYLPLIDLSNELRLSFRDILW
LKKQFHILExKFDxK-----------------------------------
-----------------------------------------------A--
------FHNQLLQSLLASIVQWNRLDRELPPVRKLAAEFLEHKLCDLDKE
FLYYQDLLNVSQVSQLGIPELGNWFWNSNLWDGSEEGPEQSQLPLVGYLS
SSNGYWMLSDETGSLPCIITGLSADKWHNNIKALSGNIVVIA--------
--------------KFQLIQ------------------------------
--------------------------------------------------
-EVFQ------------------VSK------------------------
--------------------------------------------------
--------------------------------------------------
------YTYLHFSAKDCRPFNLQNNYPTLDSLCSMCEGIQGYTHSCPKGS
IRLNPEPGPSSGDSRADHMSC----DQRECEVQRSGQELRPQHTNESSGQ
RLRLGLDCETNSLEVVVHHLSHLMVVSKGAMTTCHMLATITKRNM-----
-------LANALVVLSSTAEDGEIEVRISSNRSKRVVLLLKGPLLRSVPL
IQTGALYHLHTAEANNLFINSNHINNFSKEMKTSGLGTVPQDATFIHRGA
PLARRDYY------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------SVSEASSCEMGDGLVTVE
GIIFDRLHLEPQFPSELRSVETAGYGVP----------------------
-GRKSIVVKIRDIASAVSVCVYINRWYQRAYPIGLILGAHVALTNLQQKM
SDKTS-VYFLTSGISSVVVKDMNQPPHFES--------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-KEDWGAPCNLLMAVPSKKLLWGTVEMDQLLKVSIQFKCEYCSQPFVRGK
CSYVGCWAHSMGEITAVCT-----------------------------FK
AHHADKEALVIVKGDNVRVVLDMSENQWCQLKLLAKQTGELVYLRGSVA-
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
----------------------------------------------xxxx
xxx-----------------------------------------------
--------------------------
>Tpa
x-------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------------------------------xxx
xxxxxxFHNQLLQSLLASIVQWNTLDRELPPVRKLAAEFLEHKLCDLDKE
SMYYQDLLNVSQVSQLGIPELGNWFWNSNLWDGSEEGPEQSQLPLVGYLS
SSNGYWMLSDETGSLPCIITGLSADKWHNNIKALSGNIVVIA--------
--------------KFQLIQ------------------------------
--------------------------------------------------
-EVFQ------------------VSK------------------------
--------------------------------------------------
--------------------------------------------------
------YTYLHFSAKDCRPFNLQNNYPTLDSLCSMCKGIQGYTHSCPKGS
IRLNPEPGPSSGDFRPDHMSC----DQRECETQRSGQELRPQHTNESSGQ
RLRLGLDCETNSLEVVVHHLSHLMVVSKGAMTTCHMLATITKRNM-----
-----------------------------SNRSKRVVLLLKGPVLRSVPL
IQTGALYHLHTAEANNLFINSNHINNFSKEMKTSGLGTVPQDATFIYRGA
PLARRDYY------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------SVSEASSCDMGDGLVTVE
GIIFDRLHLEPQFPSELRSVETAGYGVP----------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-------------------------------------------------x
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx----------------
--------------------------------------------------
-----------------------xxx------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------
>Tbi
MEKELTSVQSMMKRHHEEEAAQGVKTTQRPMAQKKGRVTAISHVLNSKAY
FVHIVTYSRKRGGIGVHEIVERWEEQITKQSGHGSKVFFLELFTDPQDVL
HVASSLESQAVWLTQINIDSSYCFTHLQPRQIVFK---------------
----------------------------PKRNII----------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------LxxxxD
TQHPLSANPDTQHPLSANPDTQHPLSAVPDTQHPLSAVPDTQHPANGQVF
FHRTEASSWFGKPVKYLSALKLKKAALSKSMIVTISFxxSNPTLKCRQGY
VTDVFRPLAMFQLDNKLNFCTAMMMKVSDVPQLCVGQRVIVYNVHCVSRD
LMMCARSRVSIVPHPEQSVPAGVPGREAEKYLPLIDLSNELRLSFRDILW
LKKQFHILE----EK-----------------------------------
-----------------------------------------------A--
------FHNQLLQSLLASIVQWNTLARELPPVRKLAAEFLEHKLCDLDKE
SMYYQDLLNVSQVSQLGIPELGNWFWNSNLWDGSEEGPEHSQLPLVGYLS
SSNGYWMLSDDTGSLPCIITGLSADKWHNNIKALSGNIVVIA--------
--------------KFQLIQ------------------------------
--------------------------------------------------
-EVFQ------------------VSK------------------------
--------------------------------------------------
--------------------------------------------------
------YTYLHFSAKDCRPFNLQNNYPTLDSLCSMCEGIQGYTHSCPKGS
IRLNPEPGPSSGDSRPDHxxx----DQRECETQRSGQELRPQHTNESSGQ
RLRLGLDCETNSLEVVVHHLSHLMVVSKGAMTTCHMLATITKRNM-----
-----------------------------SNRSKRVVLLLKGPLLRSVPL
IQTGALYHLHTAEANNLFINSNHINNFSKEMKTSGLGTVPQDATFIHRGA
PLARRDYYxxSEIPTLPYNMPIKGNTLLIVGLATNREQDRT---------
--------EHITSPV---------------SDMSLVAKEH----------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----IASPVSNMSLVAKEHTIS---DMSLVVSVSEASSCEIGDGLVTVE
GIIFDRLHLEPQFPSELRSVETAGYGVP----------------------
-GRKSIVVKIRDIASAVSVCVYINRWYQRAYPIGLILGAHVALTNLQQKM
SDKTS-VYFLTSGISSVVVKDMNQPPHFESxKxSLGSLSRPA--------
--------------------------------------------------
--------------------------------GTETERVETFGSAHTRND
---------------------------------CFILVAFTTKHNTFYxI
LKEDWGAPCNLLMAVPSKKLLWGTVEMDQLLKVSIQFKCEYCSQPFIRGK
CSYVGCWARSMGEITAVCT-----------------------------FK
AHHADKEALVIVKGDNVRVVLDMSENQWCQLKLLAKQTGELVYLRGSVAP
PGISTDRAKLAFWLFCKVVVANQLKLLHIKVKKYPATPADPTKNIPVLCC
VDIKE---------------------------------------------
-----------------DRPKILNSFTxQE--------------------
--------------------------------------------------
--------------------------------------------------
--LxAIxGxxxx--------------------------------------
-------------------------x
>Tte
MEKELTSVQSTMKRHHEEEAAQGVKTTQRPMAQKKGRVTAISHVLNSKAY
FVHIVTYSRKRGGTGVHEVVERWEEQITKQSGHGSKVFFLELFTDPQDVL
HVASSLESQAVWLTQINIDSSYCFTHLQPRQIVFKF--------------
-----------------------xxxxx----------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------PMSAVPDTQHPLSAVPDTQHPANCQVF
FHRTEASSWFGKPVKYLSALKLKKAALSKSMIVTISFPMSNPTLKCRQGY
VTDVFRPLAMFQLDNKLNFCTAMMMKVSDVPQLCVGQRVIVYNVHCVSRD
LMMCARSRVSIVPHPEQSVPAGVPGREAEKYLPLIDLSNELRLSFRDILW
LKKQFHILExKFDxK-----------------------------------
-----------------------------------------------A--
------FHNQLLQSLLASIVQWNTLDRELTPVRKLAAEFLEHKLCDLDKE
SMYYQDLLNVSQVSQLGIPELGNWFWNSNLWDGSEEGPEHSQLPLVGYLS
SSNGYWMLSDETGSLPCIITGLSADKWHNNIKALSGNIVVIA--------
--------------KFQLIQ------------------------------
--------------------------------------------------
-EVFQ------------------VSK------------------------
--------------------------------------------------
--------------------------------------------------
------YTYLHFSAKDCRPFNLQNNYPTLDSLCSMCEGIQGYTHSCPKGS
IRLNPEPGPSSGDSRPDHxxx----DQRECETQRSGQELRPQHTNESSGQ
RLRLGLDCETNSLEVVVHHLSHLMVVSKGAMTTCHMLATITKRNMETWQN
SNTLHVDVS-------------------QSNRSKRVVLLLKGPLLRSVPL
IQTGALYHLHTAEANNLFINSNHINNFSKEMKTSGLGTVPQDATFIHRGA
PLARRDYYxxSEIPTLPYNMPIKGNTLLIVGLATNREQDRT---------
--------EHITSPVSDMSLVAKEHTVSPIxxxxxVAKEH----------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----IASPVSNMSLVAKEHTIS---DMSLVVSVSEASSCEIGDGLVTVE
GIIFDRLHLEPQFPSELRSVETAGYGVP----------------------
-GRKSIVVKIRDIASAVSVCVYINRWYQRAYPIGLILGAHVALTNLQQKM
SDKTS-VYFLTSGISSVVVKDMNQPPHFES--------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-KEDWGAPCNLLMAVPSKKLLWGTVEMDQLLKVSIQFKCEYCSQPFIRGK
CSYVGCWARSMGEITAVCTWDGMETWVNILWDSLVVVSIVENSRKGGNFK
AHHADKEALVIVKGDNVRVVLDMSENQWCQLKLLAKQTGELVYLRGSVAP
PGxSTDRAKLAFWLFCKVVVANQLKLLHIKVKKYPATPADQTKNIPVLCC
VDIKE---------------------------------------------
-----------------DRPKILNSFTPQExSLYxxxxWFxxxxxxxQxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxCRxxxx
xRGVxxxVDELxxExTPKxxxxxPDSVKKELLxKIKIQLTxxxxxxx---
--------------------------------------------------
--------------------------
>Tce
x-------------------------------------------------
-------------------------------------FFMELLTEPQAVV
YVTSSLESQTVWLTQININSSYCFTHLQPRQIVFKxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxx--------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
VTDVFRPLAMFQLDNKLNLCAALMVKVSDVPELCVGQHVIVYNAHCVSRD
LMMCARSRVSIVPHPEQSVPAGAPGREVEKYLPLIDLSNELRLSFRDILW
LKKQFHILExKFDEKFLFSLTIPRRVTLLPLDT-----------------
----------------------------------YLPSCNISPCLxxA--
------FHNQLLQNLLAAIVQWNTLDRELRPVRKLAAEFVDHDLCDLDKE
SGYYQDLLNVSQVSQLGIPELENWFWRSNLWDGSEEGRERSLIPLVGYLS
SSNGYWMLSDETGSLPCIITGLSADKWHNIVKALSGNIVVIT--------
--------------KFQLIQ------------------------------
--------------------------------------------------
-EVFQ------------------VTK------------------------
--------------------------------------------------
--------------------------------------------------
------YTYLHFSTKDCRPFNLQNNYPTLDSLCSMCEGIPGYTHSCPKGS
VRRNPEPGPSNGDxxx---------SQRDCETQRSGQELRPQRANESSVQ
RSRPGLDCETDSLEVVVHHLSHLMVVCKGTMTTCHMQATITKRNM-----
-----------------------------PNRSKRVTLLLKGPLLKSVPL
IQIGALYHLHTAEADNLFINSNHINNFSREMKTSGLRTVPQDATFIHCGA
PLACSDYY------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------SVSEASSCEVGDELTNVE
GIIFDRLHNELKYPSELRSIETAGYGVP----------------------
-GGKSIIVKIRDIASAVSLSVYINSWYQRAYPIGLILGAHVAFTNLQQKM
SVKNS-VYFVTTGLSSVVVKDMNRPPHFES--------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-KEDWGAPCNLLLAVPSKKLLWGTVEMDQLLKVSVQFRCEYCSHLFIRGR
CSYVGCWSHSKGEIAAVCT-----------------------------FK
AHHADKEALVIVKGDNVRVVLDMSENQWCQLKLLAKQAGELVYLRGSVAP
PDISTCRAQHVFWLYCKVVVAEQMKLLHIQAKKFP---------------
----xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxAIxxxxxxxLx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx--------------------
--------------------------------------------------
--------------------------------------------------
--xxxxxxxxxxxxxxxxxxxxxxxxxxxISxxxxxSSTASLLRSWTLYM
DIKxxxxxLNSFPPQELDAIYxxxxx
>Tps
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------xxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxA--
------SHNQLLQSLLESIVKWNASDRELRPVRKLSAEFLDHELCDLDRE
SAHYQDLLSVSQVSQRGIPELKDWFWNSNSWDGSEGGREQSPLPLVGYLS
SSNGYWMLSDETGSLPCIVTGLSADRWHNIVKALSGNI------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
---xxxYTYLHFSAKDCRPFDLQNNYPTLDSLCSTCEGIPGYTHSCPEGS
IRLDPEPGPSNA----xxxxxxxxxSQRDCETRRSDQELRPQRANGSSGQ
R-------ETDSLEVVVHHLSHLMVVCKGTMPTCHMLATIVKRNV-----
-----------------------------SHRSKRVILLLKGPLLRSVxx
xxxxxxxxxxxxxxxxxx--xx----------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------
>Tdi
x-------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------VPAGAPEREPEKYLPLIDLSNELRLSFRDILW
LKKQFHILExKFDxRFLFSLTIPRRVTLLPLGTELEYVxxSxxx------
--------------------------------------------------
------SHNELLLRLLESIVKWNASDRELRPVRKLSAEFLDHELCDLDRE
SAHYQDLLSVSQVSQRGIPELKDWFWNSNSWDGSEGGREQSPLPLVGYLS
SSNGYWMLSDETGSLPCIVTGLSADRWHNIVKALSGNIVTLSxxxxxxTG
DATVKWECLPGDTVRWxxxxxTLSxxSVFLTDTLLIGPSLCLLCTKLAET
QRCPCFVSVRLLESNRALVLCLGDHVHGVLVSCLRWLLESNRVLVVTRYT
xxxxx------------------xxxxAREESCSCGVFRGSCTRCPCFVS
VRLLESNCVLVLCLGDHVHDVLVSRLCTRCPCFVSVRLLESNxALVVCSG
NQVHGVLVSCLVRLLExxxARVVFRGSCTRCPxxVxVRLxxxNCVLVLxx
xxxxxxYTYLHFSAKDCRPFDLQNNYPTLDSLCSTCWGTPGYTHSCPEGS
IRLDPEPGPSNA----xxxxxxxxxSQRDCEPRRSDQELRLQRANGSSGQ
R-------ETDSLEVVVHHLSHLMVVCKGTMPTCHMLATIVKRNV-----
-----------------------------SHRSKRVILLLKGPLL-----
--------------------SNHINNISREIKTSGLRTVPQDATFIHRGV
PLARRDCY------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------SVSEARSCELGDELITVE
GIIFDRLHCEPQFPSEQRSVETAGYGVPxxTLxxxxxxxxxxxLTxxxxx
xGCKTIIVKIRDMASAVSVSVYINSWYQRAYPIGLIPGAHVVLTNLQQKM
SAKNSxVYFLTSGTSSVAVKDMNWPPHFESx----xxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxSQT
PQxxxxxxxxxExxxxxxxxxxxxxxxxxxGxxxxxxx------------
--------------------------------------------------
-xxxxxxxxxx---------------------------------------
--------------------------------------------------
--------------------------------------------------
--xxxxxxx-----------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-------------------------x
>Tms
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
SGYHQDLLNVSQVSQLGIPELENWFWRSNLWDGSEEGRERSLIPLVGYLS
SSNGYWMLSDETGSLPCIITGLSADKWHNIVKALSGNIVVIT--------
--------------KFQLIQ------------------------------
--------------------------------------------------
-EVFQxTLSSERGCLPIPxxxxxVTK------------------------
--------------------------------------------------
--------------------------------------------------
------YTYLHFSTKDCRPFNLQNNYPTLDSLCSMCEGIPGYIHSCPKGS
VRRNPEPGPSNGDxxx---------SQRDCETQRSGQELRPQRANESSVQ
RPRPGLDCETDSLEVVVHHLSHLMVVCKGAMTTCHMQATITKRNM-----
-----------------------------PNRSKRVTLLLKGPLLKSVPL
IQIGALYHLHTAEADNLFINSNHINNFSREMKTSGLRTVPQDATFIHCGA
PLACSDYYxx-----------------------------xxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-------------------------x