>Tge
M-------------------------------------------------
--------------------------------------------------
------------------------------------EDADECCFYDAVSE
IPLSKPRMGNTAGAEGTKGGGRPGLTDEFPIVPVIDPRQDDSEEDDTSxx
xxxxxx--------------------------------------------
--------------------------------------------------
-------------------SVVEEKIVRNLRKDVLATPPKDEEPDGEVSD
VSSSALGNIPQSSPGSGKSSVSTEE--------xxxxxxxxxKTVEDTLL
AAESGCDRADSQDSRKCLDEAPSEESANQVVGSDPTGSSVIDNSAAGSGS
NKKVNIGHYITDISKEEERLVSKLEDEKGEYIDIIPKNKDIVGELGDVKE
EDGKKNDVVGxxxxxxxxxxxxxxxxxxxxxxxxVKEEDGKKNDVVSELG
DVKEEAGKKNDTVDELGDVKEEAGKKNDTVNxxxxxxxxxxxxxxxxxxx
xxxxxxxxxKNDVVDELGDVKExxxxxNDVVDELGDVKEEDGxxxxxxxx
xxxVxxxxxxxxxxxxxxGDVKExxxxxxxxxxxxxxxxxx---------
--------------------------------------------------
-------------------------------------------DGKKNYV
VGEIRAANDDNRGVKRIENVPGQ-FWEESKTENEDTADINGMKEDAVDKA
VNRNDGDYS-EDSDGYDLENDEDINNKHRSKGNMVDETENEEDAEYLNNF
LGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFT-
----------------AEPGNRTPRVAASVNRSSSLLSGGGNNSYHSSRR
SSEDSLEEGISLRDVRVTV-------------------------------
----CVSVVLCIEHECCV---------------CEQHELKEVEDKFRKAM
IQNAQLDNEKASLTYQVELLKDRLEDLEESHSQLQRENRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQ-----------EKGLIIVGDDQLSSE
DESVGEDSPKKPPKRALVSIESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGASLNGPDTDFEDIQREANKLLGDYK
FKLQKAExxxxxLQANANVSTNFRLHLHYKQ-------------------
----------DVSTLQANVSTNFRLHLHYKQDVSTLQANVSTNFRLHLHY
KQDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQREVRELT
QQLSQAEAAKAALTHQFDQLMx----------------------------
----------------------------------------------xxx
>Tms
M-------------------------------------------------
--------------------------------------------------
------------------------------------EDADECCFYDAVSE
IPLSKPRMGNTAGVEGTKGGGRPGLADEFPIVPVIDLRQDDS--DDTx--
-----xx-PEISSRFSDKSAPIDSDKESSTSLNDQSDLDERDDSGRPSMA
VSQRDPRCTEASVGADISGEEDAGVATFDDEGSLRVDRVVARGGDLGVNL
PDTFGESTTEDCEVQSVDDPVVKEKIVRTLCKDVLTTPPKDEEPVGDVSD
VSSSALGDIPRSSPDSDKASVSTEEDTLVSKDKG--------KTVEDTLL
AAESCCDGADSQDSRKCLDEAPSEESANQV------GSSAIENSASGSGS
SKKVDIGNDITDISKEEEGLVSKVEDEKGKDIDKIPKNRDIVGELGDVKE
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------xxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxNYIVGEFVGVKEED------------------xxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxDGRKNDV
VGESGSGNDDNKGVKRVENLPGYIFWEESKKGKEDTADINGMKENAIDKA
VDRNDGDYTTEDSDGYDLDDDEDINNKYRSKGNVVDETENEEDADCLNNF
LGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFT-
----------------AEPGNRTPRVAASVNRSSSLLSGGGNNSYHSSRR
SSEDSLEEGISLRDVR----------------------------------
------------------------------------HELKEVEDKFRKAM
IQNAQLDNEKASLTYQVELLKDRLEDLEESHSQLQREHRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQ-----------EKGLIIVGDDQLSSE
DESVGDDSPKKPPKRALVSIESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGASLNGPDTDFEDIQREANKLLGDYK
FKLQKAE-------------------------------------------
--------------------------------------------------
-QDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQREVRELT
QQLSQAEAAKAALTHQFDQLICxx--------------------------
-----xREEGLREAQSRVEELEVSNSHLQRRLDKLKNAKSALLKEL---
>Tce
M-------------------------------------------------
--------------------------------------------------
------------------------------------EDADECCFYDAVSE
IPLSKPRMGNTAGVEGTKGGGRPGLADEFPIVPVIDPRQDDS--DDTx--
-----xx-PEISSRFSDKSATIDSDKESSTSLSDQSDLDERDDSGRPSMA
VSQRDPRCTEASVGADISGEEDAGVATFDDEGSLRVDRVVARGGDLGVNL
PDTFGESTTEDCEVQSVDDPVVKEKIVLTLCKDVLATPPRDEEPVGDVLD
VSSSALGDIPRSSPDSDKASVSTEEDTLVSKDKG--------KTVEDTLL
AAESCCDGADSQDSRKCLDEAPSEESANQV------GSSAIENSASGSGS
R---------------------------------------------DVKE
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------xxxxxxx--------------------
--------------xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxx---------------------------------
---------------------GYIFWEESKKGKEDIADINGMKENAIDKA
VDRNDGDYTTEDSDGYDLDDDEDINNKYRSKGNVVDETENEEDADYLNNF
LGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFT-
----------------AEPGNRTPRVAASVNRSSSLLSGGGNNSYHSSRR
SSEDSLEEGISLRDVR----------------------------------
------------------------------------HELKEVEDKFRKAM
IQNAQLDNEKASLTYQVELLKDRLEDLEESHSQLQREHRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQ-----------EKGLIIVGDDQLSSE
DESVGDDSPKKPPKRALVSIESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGASLNGPDTDFEDIQREANKLLGDYK
FKLQKAE-------------------------------------------
--------------------------------------------------
-QDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQREVRELT
QQLSQAEAAKAALTHQFDQLICxx--------------------------
-----xREEGLREAQSRVEELEVSNSHLQRRLDKLKNAKSALLKEL---
>Tps
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------------------REHRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQ-----------EKGLIIVGDDQLSSE
DESVGDDSPKKPPKRALVSIESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGASLNGPDTDFEDIQS----------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-------------------------------------------------
>Tdi
M-------------------------------------------------
--------------------------------------------------
------------------------------------EDADECCFYDAVSE
IPLSKPRMGNTAGAEGTKGGGRPGLSDEFPIVPVIDPRQDDS--DDTS--
-----xxxPEI------RSAPIDSDKESSTSLSDQSDLDERDDSGRPSMA
VSRRDQRCTEASVGADSSGEEDAGVATFDDEGSLRVDRAVAKGVDLGVNL
PDTFGESTTEDCEVQSVDDPVAEEKIVRNLRKDVLATPPKNEEPDGEVSD
VSSSALGDVPRSSPDGDKSSVSTEEDNLVSKNNG--------KTVEDTLL
AAESGCDGADSQDSRKCLDEAPSEESANQV------GSSVIDNSASGSGS
SKKVDIGNDVTDISKEEERLISKVEDKKEEDIDKIPKNKDIVGELKDVKE
EDGKQNDIVG----------------------------------------
--------------------------------------------------
---------------ELGDxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxIKEExxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx---------
--------------------------------------------------
-------------------------------------------DGKKKDV
VGELGSDNDDNRGVKRVENVPGNLFWEESKKGKEDTADINGMKEDAIDKA
VDINDGDYTTEDSDGYDLDDDEDINNKYISKGNVVDETENEEDADYLNNF
LGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFT-
----------------AEPGNRTPRVATSVNRSSSLLSGGGNNSYHSSRR
SSEDSLEEGISLRDVRGSVxxxxxxxxPVQLDLAPSLNGKDIRKSDMHPN
LxxxCVSVxxCVEHKCCV---------------CEQHELKEVEDKFRKAM
IQNAQLDNEKASLTYQVELLKDRLEDLEESHSQLQREHRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQ-----------EKGLIIVGDDQLSSE
DESVGDDSPKKPPKRALVSIESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGASLNGPDTDFEDIQREANKLLGDYK
FKLQKAE-------------------------------------------
--------------------------------------------------
-QDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQRE-----
--------------------------------------------------
----------xxxAQSRVEELEVSNSHLxxxLDKLKNAKSALLKEL---
>Tcm
M-------------------------------------------------
--------------------------------------------------
------------------------------------EDADECCFYDAVSE
IPLSKPRMGNTAGAEGAKGGGRPGLADEFPIVPVIDPRRDDS--DDTS--
-----SxxPEISSRSSDKSAPIDSDKESSTSLSDQSDLDERDDSGRPSMA
VSQRDQRCTEASVGADSSGEEDAGVATFDDEGSLRVDRAVAKGVDRGVNL
PDTFGESTTEDCEVQSVDDPVVEEKIVRNLRKDVLATPPEDGE-------
-------------xxxDKSSVSTEEDNLVLKDTG--------KTIEDTLL
AAESGCDRADSQDSRKCLDEAPSEE------------SSVIDNSASRSGS
SKEVDIGYDVTDISKEEERLVSKVEDEKGEYIDKIPKNKDIVGELKDVKG
EDGGKNDIVG----------------------------------------
--------------------------------------------------
---------------ELGxxxxxxxxxxxxxx------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--ELGSANDDNRGVKRVENVPGNLFLEESKKGKEDTADINGMKEDAIDKA
VDRNDGDYTTEDSDGYDLDADEDINNKYRSKENLVDETENEEDADYLNSF
LGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFT-
----------------AEPGNRTPRVAASVNRSSSLLSGGGNNSYHSSRR
SSEDSLEEGISLRDVR----------------------------------
--------------------------------------------------
-----------------------------------REHRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQ-----------EKGLIIVGDDQLSSE
DESVCDDSPKKPPKRALVSVESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGASLNGPDTDFEDIQREANKLLGDYK
FKLQKAE-------------------------------------------
--------------------------------------------------
-QDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQREVRELT
QQLSQAEAAKAALTHRFDQLMC----------------------------
----------------------------------------------xxx
>Tsi
M-------------------------------------------------
--------------------------------------------------
------------------------------------EDADECCFYDAVSE
IPLSKPRMGNTAGAEGAKGGGRPGLADEFPIVPVIDPRRDDS--DDTS--
-----SxxPEISSRSSDKSAPIDSDKESSTSLSDQSDLDERDDSGRPSMA
VSQRDQRCTEASVGADSSGEEDAGVATFDDEGSLRGDRAVAKGVDLGVNL
PDTFGESTTEDCEVQSVDDTVVEEKIVRNLRKDVLATPPEDEEPDGEVSD
VSSSALGDIPRSSPDGDKYSVSTEQDTLVSKDNG--------KTVEDTLL
AAESGCDRADSQDSRKCLDEAPSEE------------SSVIDNSASRSGS
SKEVDIGYDVTDISKEEERLVSKVEDEKGEYIDKIPKNKDIVGELKDVKE
EDGKKNDIVG----------------------------------------
--------------------------------------------------
---------------ELGDxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxx-------------------------------------------
--------------------------------------------------
-------------------------------------------xxxxxxx
VEELGSANDDNRGVKRVENVPGNLFWEESKKGKEDTADINGMKEDAIDKA
VDRNDGDYTTEDSDGYDIDADEDINNKYRSKENVVDETENEEDADYLNNF
LGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFT-
----------------AEPGNRTPRVAASVNRSSSLLSGGGNNSYHSSRR
SSEDSLEEGISLRDVR----------------------------------
-----------------xxxxxxxxxxxxxxxxCEQHELKEVEDKFRKAM
IQNAQLDNEKASLTYQVELLKDRLEDLEESHSQLQREHRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQVTLLFPSFFLSEKGLIIVGDDQLSSE
DESVGDDSPKKPPKRALVSVESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGASLNGPDTDFEDIQREANKLLGDYK
FKLQKAE-------------------------------------------
--------------------------------------------------
-QDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQREVRELT
QQLSQAEAAKAALTHQFDQLICxxxWQxxGWWGVQRSQMTTPVIMAAYPD
YRLHxx----LREAQSRVEELEVSNSHLQRRLDKLKNAKSALLKEL---
>Tte
MT------------------------------------------------
------------------------GPRCTTLKEVPSHEGHAPFQAEFRRV
LFSPRYPLECAVDGRLLSRVRFLGIRACLLTSSSLVRDADECCFYDAVSE
IPLSKPRMGNTAGAEGTKGGGRPGLTDEFPIVPVIDPRQEDSEEDDTS--
-----SSNPEISSRFSDKSAPIDSDKESSTSLSDKSDLDERDGSGRLSMA
VSSRDPRCVEASVGADSSGEEDAGVATFDDEGSLRVDHAATRGGDLGVNL
PDTFGESTTEDCEVQSVDDSVVEEKIVRNLRKDVLATPPKDEEPDSEVSD
VSSSALGNIPQSSPGCDKSSVSTEE--------GVVVSKYIVKTVEDTLL
AAESGCDRADSQDSRKCLDEAPSEESANQVVGSDPTGSSVIDNSAAGSGS
NKKVDIGNYITDISKEEERLVSKVEDEKGEDIDIIPKNKDIVGELGDVKE
EDGKKNDVVN----------------------------------------
--------------------------------------------------
---------------ELGDEKVxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxVKVE-------------------------------------------
--------------------------------------------------
-------------------------------------------DGKKNDV
xGELGAANYDNRGVKRVENVPGQ-FWEESKNGNEDTADINGMKEDAVDKA
VNRNDGDNSTEDSDGYDLENDEDINNKHRSKGNMVDETENEEDAEYLNNF
LGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFT-
----------------AEPGNRTPRVAASVNRSSSLLSGGGNNSYHSSRR
SSEDSLEEGISLRDVRVTV-------------------------------
----CVSVVLCIEHECCV---------------CEQHELKEVEDKFRKAM
IQNAQLDNEKASLTYQVELLKDRLEDLEESHSQLQRENRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQ-----------EKGLIIVGDDQLSSE
DESVGEDSPKKPPKRALVSIESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGANLNGPDTDFEDIQREANKLLGDYK
FKLQKAE-------------------------------------------
--------------------------------------------------
-QDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQRE-----
--------------------------------------------------
----------xxxAQSRVEELEVSNSHLQRRLDKLKNAKSALLKEL---
>Tbi
MxxVTSxRDEPxRAPFKSTCLILVGAKSLSVTSSFVLKYDWTSVYDLERG
TVRLTIKTxxxxSASLxxxxVGRGG-------RVPSHEGHAPFQAEFRRV
LFSPRYPLECAVDGRLLSRVRFLGIRACLLTSSSLVRDADECCFYDAVSE
IPLSKPRMGNTAGAEGTKGGGRPGLTDEFPIVPVIDPRQEDSEEDDTS--
-----SSNPEISSRFSDKSAPIDSDKESSTSLSDKSDLDERDGSGRLSMA
VSSRDPRCVEASVGADSSGEEDAGVATFDDEGSLRVDHAATRGGDLGVNL
PDTFGESTTEDCEVQSVDDSVVEEKIVRNLRKDVLATPPKDEEPDSEVSD
VSSSALGNIPQSSPGCDKSSVSTEE--------GVVVSKYIVKTVEDTLL
AAESGCDRADSQDSRKCLDEAPSEESANQVVGSDPTGSSVIDNSAAGSGS
NKKVDIGNYITDISKEEERLVSKVEDEKGEDIDIIPKNKDIVGELGDVKE
EDGKKNDVVN----------------------------------------
--------------------------------------------------
---------------ELGDEKVxxxxxxxxxxxxxx--------------
---VKVE-------------------------------------------
--------------------------------------------------
-------------------------------------------DGKKNDV
VGELGAANYDNRGVKRVENVPGQ-FWEESKNGNEDTADINGMKEDAVDKA
VNRNDGDNSTEDSDGYDLENDEDINNKHRSKGNMVDETENEEDAEYLNNF
LGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFT-
----------------AEPGNRTPRVAASVNRSSSLLSGGGNNSYHSSRR
SSEDSLEEGISLRDVR----------------------------------
------------------------------------HELKEVEDKFRKAM
IQNAQLDNEKASLTYQVELLKDRLEDLEESHSQLQRENRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQ-----------EKGLIIVGDDQLSSE
DESVGEDSPKKPPKRALVSIESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGANLNGPDTDFEDIQREANKLLGDYK
FKLQKAE-------------------------------------------
--------------------------------------------------
-QDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQREVRELT
QQLSQAEAAKAALTHQFDQLML----------------------------
----------------------------------------------xxx
>Tpa
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
---xxNDVVx----------------------------------------
--------------------------------------------------
---------------xxxx-------------------------------
---xxxx-------------------------------------------
--------------------------------------------------
-------------------------------------------xxxxxxx
xxEIRAANDDNRGIKRVENVPGQ-FWEESKNGNENTADINGMKEDAVDKA
VNRNDGDFSTEDSDGFDLENDEDINNKHRSKGNMVDETENEEDAEYLNNF
LGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFTV
IDQHHLMLSLRALCSVAEPGNRTPRVAASVNRSSSLLSGGGNNSYHSSRR
SSEDSLEEGISLRDVR----------------------------------
------------------------------------HELKEVEDKFRKAM
IQNAQLDNEKASLTYQVELLKDRLEDLEESHSQLQRENRDKCREHDQLKR
ASAKLKEDMEWYKAQLEERDRLIQ-----------EKGLIIVGDDQLSSE
DESVGEDSPKKPPKRALVSIESAEMLETAGEGSLDVRLRRFAEERNELLD
QVRHLKLELEEERSRHKSDAKRIPGASLNGPDTDFEDIQREANKLLGDYK
FKLQKAExxxxxLQ--ANxxxxxxxxxxxxxxVSTLQANxSTNYRLHLHY
NxDVSTLQAxDVSTLQANVSTNYRLHLHYNQDVSTLQANVSTNFRLHLHY
NQDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQREVST--
--------------------------------------------------
-------------------------------------------------