>Tge
M-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--SGDSHITLPYR-----------CYSPRPHLG----------SLLEMFGHVLKGLHKSG
FKKPSPIQLKAIPLGRCG------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------LDL
VMQAKSGTGKTCVFTILALEMLINTPSLQVLILAPTREIAVQITHVIRDIGQCIKGMKVE
SFIGGLPYHEDVKKVEGCQIAVGAPGRIKHLIEAGCMKTDLVRLFVMDEADKLMDDTFVK
DINYIFWKLPDNKQMIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHANVAAQVKIKIERLMELLSSVTFQQCVVFSNYQTRAESICNRLNANGWPAMSITGSQD
QYARLKAITCLREFRCRVLLSTDLTSRGIDAENVNLIVNFDVPYSGTTYLHRIGRAGRYG
SHGISITLVAEDKELLEFQQMLGLIGGNSMSIARLSRESLKKDLWQCDYSLLKSVHGIVK
TAECSHENNEDV-------ENNMSQK----------------------------------
------------------------------------------------------------
--------------------------------------------ESKSSKDDFDYKKLSI
YNETVKHLHENNQMSLSKLSNEYK--DTKSLLEYLVSPDDLGEVLERRVMCDDGDTFVNS
NNKKGIEPPNEPNSSRTEIYNDNISS-SCYEDFSKKVNLTCSSGKKARGLRSMIEAKGGS
REYLMSRGQQ-GELL---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------
>Tms
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MHF-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------VGLKVE
SFIGGLPYHEDVKKAEGCQIAVGAPGRIKHLIEAGCMKTDLVRLFVMDEADKLMDDTFVK
DINYIFWKLPDNKQMIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHTNVAAQVKIKIERLMELLSSVTFQQCVVFSNYQTSGCAMLHRGEWRGDLPISAVGS--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------FL-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------
>Tsi
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MHF-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------VGLKVE
SFIGGLPYHEDVKKVEGCQIAVGAPGRIKHLIEAGCMKTDFVRLFVMDEADKLMDDTFVK
DINYIFWKLPDNKQMIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHTNVAAQVKIKIERLMELLSSVTFQQCVVFSNYQTRAESICNRLNANGWPAMSITGSQD
QYARLKAITCLREFRCRVLLSTDLTSRGIDAENVNLIVNFDVPYSGTTYLHRIGRAGRYG
SHGISITLVAENKELLEFQQMLGSIGGNSMSIARLSRESLKEDLWQCDYSVFKSVHGIVT
TSECSHENNEDG------------------------------------------------
------------------------------------------------------------
----------------------------------------------QVSVDLVD----GV
HNYQLKLVVDQTALFL---------------VHWLLS-----------------------
----------------------NIAD----------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------Y--
-----------------------
>Tcm
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MHF-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------VGLKVE
SFIGGLPYHEDVKKVEGCQIAVGAPGRIKHLIEAGCMKTDFVRLFVMDEADKLMDDTFVK
DINYIFWKLPDNKQMIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHTNVAAQVKIKIERLMELLSSVTFQQCVVFSNYQTRAESICNRLNANGWPAMSITGSQD
QYARLKAITCLREFRCRVLLSTDLTSRGIDAENVNLIVNFDVPYSGTTYLHRIGRAGRYG
SHGISITLVAENKELLEFQQMLGSIGGNSMSIARLSRESLKEDLWQCDYSVFKSVHGIVT
TSECSHENNEDG------------------------------------------------
------------------------------------------------------------
----------------------------------------------QVSVDLFD----GV
HNYQLKLVVDQTALFL---------------VHWLLS-----------------------
----------------------NIAD----------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------Y--
-----------------------
>Tps
MYSSLLHHLVRVKKKAKTLARFVRFHSTEKLYQFCPTAKMVSTTILALIVTIVGYRSTVQ
TQIAMELVMCSCNMVKDHLPSYRAEDSQPSSSSLATKTLYLNDKQNKHKLCRVYRAERCV
ATGLILTVKKVNSLHDTAMTKSYATAWLTP--EYYTQSWVIAVSHSPTWA----------
--HSQKCLVSTALSQHFKSRKTAHSLASKPRTKDIFINEDVYFSGMMLSGHVLKGLHKSG
FKKPSPIQLKAIPLGRCG------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------LDL
VMQAKSGTGKTCVFTILALEMLINTPSLQVLVLAPTREIAVQITHVIRDIGQCIKGLKVE
SFIGGLPYHEDVKKVEGCQIAVGAPGRIKHLIEAGCMKTDHVRLLVMDEADKLMDDTFVK
DINYIFWKLPDNKQMIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHTNVAAQVKIKIERLMELLSSVTFQQCVVFSNYQTRAESICNRLNANGWPAMSITGSQD
QYARLKAITCLREFRCRVLLSTDLTSRGIDAENVNLIVNFDVPYSGTTYLHRIGRAGRYG
SHGIAITLVAENKELLEFQQMLGSIGGNGMSIARLSRESLKKDLWQCDYSVFKSVHGIVT
TSECSHENNEDVDNNKTILENNISQEGIDVGMKKKEIINQVQKESTNEFKVAK---KSRK
NKLKSNSYSKQNMKDVLPIESMQNLTLKTDGIVNEDTKSMCNAPSECLSSQSSDEIIVNK
LNVTMKDLSNILMQNTPCTTKLESYNDLIHSLQYFKSDLELNILENKGSKDDFDVNKLRN
YNETVKHLHENNQVSLSKLSNQYKDCDTKSLLEYLVSTDSLGEVLERREICDNRDRVVNS
KNKKGLEPSNELNSSRSEVYNENNNSPSCYEDFSDKVNLTCSSWKK--GFSDVIPCRGSA
SHGNSSREEEIDPILNNGGQPFSGGLINDCPKSRYNNWRFNDHTNVIPNQVSRRSH----
--------------------SGV----PHQKLHQHQHQHGARFREYN--ILRLQLVQMKH
Y-----IQYSEYM--KYMFRYR--------------------------------------
-----------------------
>Tbi
------------------------------------------------------------
---------MAVNM----------DDNNRRSSSLQLEII----KSKWSSICAMADLNVLA
YCGCQRLVELIGSTF-----APVSGAYQNPHGDIFQQFQLLTV-----WT--CLTGIML-
-----VFLTICFRSQHFKSRKTAHSLASKPRTKDIFINEDIDFSGMMLSGHVLKGLHKSG
FKKPSPIQLKAIPLGRCG------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------LDL
VMQAKSGTGKTCVFTILALEMLINTPSLQVLILAPTREIAVQITHVIRDIGQCIKGLKVE
SFIGGLPYHEDVKKVEGCQIAVGAPGRIKHLIEAGCMKTDLVRLFVMDEADKLMDDTFVK
DINYIFWKLPDNKQMIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHTNVAAQVKIKIERLMELLSSVTFQQCVVFSNYQTRAESICNRLNANGWPAMSITGSQD
QYARLKAITCLREFRCRVLLSTDLTSRGIDAENVNLIVNFDVPYSGTTYLHRIGRAGRYG
SHGISITLVAEDKELLEFQQMLGSIGGNSMSIARLSRESLKKDLWQCDYSLLKSVHGIVT
TAECSHENNEDV-------ENNMSQKGIKVGMKTKEIINEVQEESKNEIKVAKQSNKLRK
NKLKSNSYSTQNMEDVLPIESMQNLIPKTDGIVNEDEKPMCDGFSKCLSLQSSDEITVNK
LNVTMKDVSNILLKNTPCTMKLESYNDLIHSLQYFKSDLELDILESKNSKDDFDYNKLSI
YNKTIKHLHENNQMSLSKLSNEYK--DTKSLLEYLVSTDNLGEVLERRVMCDTGDTFVNS
NNKKGIEPSNEPNSSRSEIYNDNISS-SCYEDFSDKVNLTCSSGKK--GFSNVI-CRDTA
SQGNSSREDEIDPLLNTRGQTFSGGLINYCPKSRYNNWRFNNHTNVIPNQVSQRSH----
--------------------RGVHHQTSHQHQHQHQHQHSASFREYN--ILRLQLVQMKH
Y-----IQYSEYM--KYMFGYR--------------------------------------
-----------------------
>Tce
------------------------------------------------------------
---------MDVNM----------DDNNRRSLSLHTVRS----RSQLLSFSRH-------
----------------------------------------VVLCRKYTWEGPLLNGAMGM
HIFSDKFLTLCFRSQHFKSRKTAHSLASKPRTKDIFINEDIDFSGMMLSGHVLKGLHKSG
FKKPSPIQLKAIPLGRCG------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------LDL
VMQAKSGTGKTCVFTILALEMLINTPSLQVLVLAPTREIAVQITHVIRDIGQCIKGLKVE
SFIGGLPYHEDVKKAEGCQIAVGAPGRIKHLIEAGCMKTDLVRLFVMDEADKLMDDTFVK
DINYIFWKLPDNKQMIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHTNVAAQVKIKIERLMELLSSVTFQQCVVFSNYQTRAESICNRLNANGWPAMSITGSQD
QYARLKAITCLREFRCRVLLSTDLTSRGIDAENVNLIVNFDVPYSGTTYLHRIGRAGRYG
SHGISITLVAESKELLEFQQMLGSIGGNSMSIARLSRESLKKDLWKCDYSAFKSVHGIVK
TSECSHENNEDVDNNKTLLENNTSQKGINVEIKKKEIINQVQKESKNEFKVAKQSNKSRK
NKLKSNSYSTQNMKDVLPIESMQNLTLKTDGIVNEDAKSMCNVPSDCLSSQSSDEIIVNK
LNVTMKDLSNILMKNTPCTMKLESYNDLIHSLQYFKRDLELNILESKSSKDGFDVNKLRK
YNETVKHLHENNKMSLSKLSNQYKDCDTKSLLEYLVSTDNLGQVHERRDICDNRDRVVNS
NNKEGLEPSNELNSSRSEVYNDNNSSSSCYEDFSDKVNLTCSSGKK--GFSDVI-RRGSA
SQGNISREDEIDPLLNNGGQPFSGGLFNDCPKSRYNNWRFNDHTNVIPNQLISVAEDYIC
KLSYTQETIYW-------ILKMIDYTKADNTKAINNKITKEDFIAYNDMINKITFYQDSY
LR---KIDFYQYLVKRYLFNFFFELIAIIRG---VSVWRVFLVSCAASSFSVKRETVYQL
NPGSGEEAFCHMSRGISSLQYWQ
>Tpa
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHTNVAAQVKIKIERLMELLSSVTFQQCVVFSNYQTRAESICNRLNANGWPAMSITGSQD
QYARLKAITCLREFRCRVLLSTDLTSRGIDAENVNLIVNFDVPYSGTTYLHRIGRAGRYG
SHGISITLVADDKELLEFQQMLGSIGGNSMSIARLSRESLKKDLWQCDYSLLKSVHGIVT
TAECSHENNEDV-------ENNMSQK----------------------------------
------------------------------------------------------------
--------------------------------------------ESKSSKDDFDYNKLSI
YNETVKHLHENNQMSLSRLSNEFK--DTKSLLEYLISTDSLGEMLERRVMCDTGDTFVNS
NNKKGIEPSNEPNSSRTEIYNDNISS-SCYEDFSDKVNLTCSSRKK--GFSNAI-CRDTA
SQARGLRS-MIEAKGGSRGCTKTRAAEDVRGRTKYDAAKINRGTKMAVLQSISPT-----
-------------------------------------------------VKRMKP-----
-----KVR----------------------------------------------------
-----------------------
>Tte
------------------------------------------------------------
---------MAVNM----------DDNNRRS-----------------------------
------------------------------------------------------------
--SSKKFLTICFRSQHFKSRKTAHSLASKPRTKDIFINEDIDFSGMMLSGHVLKGLHKSG
FKKPSPIQLKAIPLGRCG------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------LDL
VMQAKSGTGKTCVFTILALEI---------------------------------------
------------------------------------------------------------
---YIFWKLPDNKQMIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHTNVAAQVKIKIERLMELLSSVTFQQCVVFSNYQTRAESICNRLNANGWPAMSITGSQD
QYARLKAITCLREFRCRVLLSTDLTSRGIDAENVNLIVNFDVPYSGTTYLHRIGRAGRYG
SHGISITLVAEDKELLEFQQMLGSIGGNTRGLRKVQ-----------------NVKYMGS
MIEAKGESREAV---------------LRLGQQRI-------------------------
------------------------------------------------------------
------------------------------------------------------------
----------NNLIEMQILAEHWV------------------------------------
---KQRPPVSE-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------
>Tdi
M-----------------------------------------------------------
--------TMDVNK----------DDNNRRS-----------------------------
------------------------------------------------------------
-----------LRSQHFKSRKTAHSLASKPRTKDIFINEDIYFSGMMLSGHVLKGLHKSG
FKKPSPIQLKAIPLGRCGLEQVHDLVNLSRMFCKNGRMDGDIDRRADTSWRVVGWMWTVA
KSEVVSKQTKMAGYKSVFVATLFYGYEVIEQVFLSKGQHLTLYLHCIQVEGFSILHLKTK
LFHIQSLPSEVWIREVGQEMIIIYSNVKLFHIQSLPSKVWIHEVGQEMIIIYSSVKLFHI
QSLPSKVWIHEVGQEMIIIYSSVKLFHIQSLPSEVWIREVGQEMLISYSSVKLFHQLLDL
VMQAKSGTGKTCVFTILALEMLINTPSLQVLVLAPTREIAVQITHVIRDIGQCI---KVK
CFL----------SLHTCDIEVTYIIMCWTVTDSCVSEVPEIVLLIV-----VVVDCYCY
IIN-IRTMLPDNKQMIAASATYPNSLEKAVSCYMRTPTHVSPNYDGPVLLGLRQFVMVVP
AHTNVAAQVKIKLERLMELLSSVTFQQCVVFSNYQTRAESICNRLNANGWPAMSITGSQD
QYARLKAITCLREFRCRVLLSTDLTSRGIDAENVNLIVNFDVPYSGTTYLHRIGRAGRYG
SHGISITLVAENKELLEFQQMLGSIGGN--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------KNKGSKDDFDVNKLRN
YNETVKHLHENNQVSLSKLSNQYKDCDTKSLLEYLVSTDSLGEVLERREICDNRDRVVNS
KNKKGLEPSNELNSSRSEVYNENNNSPSCYEDFSDKVNLTCSSWKK--GFSDVIPCRGSA
SHGNSSREEEIDPILNNGGQPFSGGLINDCPKAKY---------RLIWLMVFTIINSKL-
GLADTGGGFFWVWGVHCFIFEGVVWW-----------------------VIRGQRVKFIL
WRGGERTRLWVNVWARHLCGFP----EVLKGGVLLCMEFVIVLPLTAAIL----------
-----------------------