>Tge
M-------------------------------------------------
-----------------------------------------------AY-
---------FLSASKLAVTEYAKSVNGGDKNKNEDNVSRSSDSGGPPALE
LSRSLSHESNKDRKESSRNSDRSKKKSSWYTALYPTYKSRSEDFRRIFKD
VPPEERLVV-----------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------------------------DYSxxxxxx
ILVxxxxxxSxxxxxxxxxxxxxxxx------------------------
-----VSLKWKDVTAITKEKTALVIPNAVLVCTETDKLFFTSFGARDKTY
LMLFRVWQ--NALMxQ----------------------------------
---------------------------EFTESPLELPVECHLDDSLPGLL
YRHQQVSPHSPGKRVPGISSINLISENLPSDMSDTTDSDADKH-------
--------------------------------------------------
---------------------G----------------------------
--------------------------------------------------
--------------------------------------------------
--------D---------MNLSPWQQSPDSGLKQRVVTLTMPLSQSVGPK
STHVCET------------------------------------QxxxFSx
YLENSATVSRGG---NTRTTRFGGRLVQGATVAVDQTADDGEIWAQSQxx
xxxIMLPCSKPGQLYAIDSDSVNSGIPYADSFYVTTHYCITRTGDNECCL
AVYCQIKYKKNVWGIVKx--------------------------------
----------------LFVSILLVLFVSILLVLFVSILLVLFVSILLALF
VSILLALFVSILLALLLGFIEKNTWSGLEDFHTSLTKALQVECDNGTGLG
VKKKVRRRRRGLAGITPAEAARPIIGLVEGDGRTLSEMLSWGVMAILVFL
VCLNALLYYKLWVLEEWTQNSSHSFTVMDLQVLRF---------------
-----SGSFLDRDGSxxxxxxxxx--------xRSxGSQAHSxxxxxxxx
xxxxGTFLDSD-----------------------------------xxxx
xxxxxxxxxxxxxx------------------------------xxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-
--------------------------------------------------
-------xxSGTFLDRDGAxxxxx-------HSLTEMELQVL--------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------------------------------------RT
PPKSQDEWLRLLQQQEALHNVEMQKWQKVLQAAVQLLRQTEESLSELQVS
IHPLVSKKVLSVLKDTFAEEAAAA-AIKVELPAEDVVMTETSREEL
>Tpa
M-------------------------------------------------
-----------------------------------------------xxx
xxxxxxxxx-----------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
---------------x----------------------------------
---------------------------EFTESPLELPVECHLDDSLPGLL
YRHQQVSPHSPGKRVPGIGSINLISENLPSDMSDTTDSDADKH-------
--------------------------------------------------
---------------------GGxxxxxVC--------------------
--------------------------------xxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxRRYRKxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxD---------MNLSPWQQSPDSGLKQRVVTLTMPLSQSVGPK
STHVCET------------------------------------Q-----x
YLENSATVSRGG---NTRTTRLGGRMVKGATVAVDQTADYGEIWAQSQxx
xxxIMLPCSKPGQLYAIDSDSVNSGIPYADSFYVTTHYCITRTGDNECCL
AVYCQIKYKKNVWGIVK---------------------------------
--------------------------------------------------
-----------------xFIEKNTWSGLEDFHTSLTKALQVECDNGTGLG
VKKKVRRRRRGLAGITPAEAARPIIGLVEGDGRTLSEMLSWGVMAILVFL
VCLNALLYYKLWVLEEWTQNSSHSFTVMDLQVLRF---------------
-----SGTFLDRDGA-----------------------------------
--------------------------------------------------
--------------------------------------------------
---------------------------------xxxxxxxxxxxxxxxx-
--------------------------------------------------
-------xxxGTFLHRDGSxxxxx-------HSLTLMELQVL--------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------------------------------------RT
PPKSQDEWLRLLQQQEALHNVEMQKWQKVLQAAVQLLRQTEESLSELQVS
IHPLVSKKVLSVLKDTFAEEAAAA-AIKVELPAEDVVMTETSREEL
>Tbi
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------xxxxx----------SMQEMWQWVHSCYGEELGLTSDD
EDYIHPVLEEDKISNIGVPLSVDSFVEEFTESPLELPVECHLDDSLPGLL
YRHQQVSPHSPGKRVPGIGSINLISENLPSDMSDTTDSDVDKH-------
--------------------------------------------------
-----------------------------------xxxxxxxxxxxxRKI
IRSVFPVHIDQLFTLLFTSSKFFLDFHTIRRTS-----------------
--------------------------------------------------
--------D---------MNLSPWQQSPDSGLKQRVVTLTMPLSQSVGPK
STHVCET------------------------------------Q-----x
xLKNSTTVSRGGxSVNTRTTCFDGRMVKGATxAxxxxxxDGEFxxQSRxD
LLRTMLPCSKPGQLYAIDSDSVNSGIPYADSFYVTTHYCITRTGDNECCL
AVYCQIKYKKNVWGIVKxVKFKNV-----------------GLFVSILLG
LFVSILLMLIVSILLVLFISILLMLTVSILLVLFVSILLVLFVSILLTLF
VSILLGLFVSILLALLLGFIEKNTWSGLEDFHTSLTKALQVECDNGT---
-------------------------GLVEGDGRTLSEMLSWGVMAILVFL
VCLNALLYYKLWVLEEWTQNSSHSFTVMDLQVLRF---------------
-----SGTFLDRDGA--------------------xxSQVxxxxxxxxxx
xxxxxxFLHRDxxxxxxxxxxx--------------------xxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxx--------------xxxxxxxxxxxx
GTFLDCxxx------------------------Txxxxxxxxxxxxxxx-
--------------------------------------------------
-------xFSGTFLDRDGATGSxx-------HSLTMMELQVL--------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------------------------------------RT
PPKSQDEWLRLLQQQETLHNVEMQKWQKVLQAAVQLLRQTEESLSELQVS
IHPLVSKKVLSVLKDTFAEEAAAA-AIKVELSAEDVVMTETSREEL
>Tte
x-------------------------------------------------
--------------------------------------------------
--------x-----------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------xxxxxx--------------------------------------
---------------------------EFTESPLELPVECHLDDSLPGLL
YRHQQVSPHSPGKRVPGIGSINLISENLPSDMSDTTDSDVDKH-------
--------------------------------------------------
---------------------GGxxxxxVCSxQHEG-----------RKI
IRSVFPVHIDQLFTLLFTSSKFFLDFHTIRRTS-----------------
--------------------------------------------------
--------D---------MNLSPWQQSPDSGLKQRVVTLTMPLSQSVGPK
STHVCET------------------------------------Q------
--------------------------------------------------
---TMLPCSKPGQLYAIDSDSVNSGIPYADSFYVTTHYCITRTGDNECCL
AVYCQIKYKKNVWGIVKxVKFKNVGLFVS---------ILLGLFVSILLG
LFVSILLILIVSILLVLFISILLMLTVSILLVLFVSILLTLFVSILLTLF
VSILLGLFVSILLALLLGFIEKNTWSGLEDFHTSLTKALQVECDNGTGLG
VKKKVRRRRRGLAGITPAEAARPIIGLVEGDGRTLSEMLSWGVMAILVFL
VCLNVLLYYKLWVLEEWTQNSSHSFTVMDLQVLRF---------------
-----SGTFLDRDGA--------------------xGSxxHSxxxxxxx-
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------xxxx-------HSLTMMELQVL--------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------------------------------------RT
PPKSQDEWLRLLQQQETLHNVEMQKWQKVLQAAVQLLRQTEESLSELQVS
IHPLVSKKVLSVLKDTFAEEAAAA-AIKVELSAEDVVMTETSREEL
>Tms
M-------------------------------------------------
-----------------------------------------------SY-
---------FLSASKLAVTEYAKSVNRDHKNKHEDNVSRSSDSGGPPVLE
LSRSLSHESNKDRKESSRNSDRSKKKSSWYNALYPTYKSRSEDFRRIFKD
VPPEERLVVECNxxxxxxxxxQCIYIQLSLxxxxxxxxxxxxxxxxxxNS
LVSTIPGKSPxxxxxxxxPGKSPVISLVSTIxxxxxxxLSCFNxxxxxxx
LTLLFQxxxxxxxxxxxxxxxxxxxxxxxLVSTIPGKSPVISLVSTIPGK
SPxxxxxxxYPWQSNSLVSTIPGKSPVISLVSTIPGKSPVISLVSTIPGK
SPVLxxxxxxxxxxxxxxxxxxLxxxxxxxxxxxxxxxxxxx--------
--------------------------------------------------
-----VSLKWKDVTAITKEKTALVIPNAVLVCTETDKLFFTSFGARDKTY
LMLFRVWQ--NALMDQVTTYWLxxxxxSMQEMWQWVHSCYGEELGLTSDD
EDYIHPVLEEDKISNIGVPLSVDSFVEEFTESPLELPVDCHLDDSLPGLL
YRHQQVSPHSPGKRVPGIASISLLSENLPTDMSDTTDSDADKH-------
--------------------------------------------------
---------------------GGxxxxxVCSxQHEG-----------RKI
VRSIFPVHIDQLFTLLFTSSKFFLDFHTIRRTS-----------------
--------------------------------------------------
--------GxAAKLDRTxMNLSPWQQSPDSGLKQRVVTLTMPLSQSVGPK
STHVCET------------------------------------Q------
--------------------------------------------------
---IMLPCSKPGQLYAIDSDSVNSGIPYADSFYVTTHYCISRTGENECCL
AVYCQIKYKKNVWGIVK-----------x---------------------
--------------------------------------------------
------------------FIEKNTWSGLEDFHTSLTKALQVECDSGIGLG
VKKKVRRRRRGLAGITPAEVARPIIGLVEGDGRTLSEMLSWGVMAILVFL
VCLNALLYYKLWVLEEWTQNSSHSFTVMDLQVLRF---------------
-----SGTFLHCDGS------xxxxxxxxxxxxxxxxxxxxxxxxxxxxx
--------------------------------------------------
--------------------------xx----------------------
--------------------------------------------------
--------------------------------------------------
--------xxxxxxxxxxxxxxxx-------xxxxxxxxxxxx-------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------------------------------xxxxx---
------------------------------------xxxxxxxx------
----------xxxxxxxxxxxxxxxxxxxxxxxxxx--------------
-----xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-----RT
PPKSQDEWLRLLQQQEALHNVEMQKWQKVLQAAVQLLRQTEESLSELQVS
IHPLVSKKVLSVLKDTFAEEAAAAxALRGELPAEDVVTTETSREEL
>Tps
MxxxxxxxxxxxxPxxxxxxxxxxx-xxxxxxxxx--xxxxxxxxL----
----------------------------------------RRCWRCVx--
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
----------------------GxxxxxVCSxQHEG-----------RKI
VRSVFPVHIDQLFTLLFTSSKFFLDFHTIRRTS-----------------
--------------------------------------------------
--------D---------MNLSPWQQSPDTGLKQRVVTLTMPLSQSVGPK
STHVCETx------------------------------xxLSVQ------
--------------------------------------------------
---IMLPCSKPGQLYAIDSDSVNSGIPYADSFYVTTHYCISRTGENECCL
AVYCQIKYKKNVWGIVK-----------xxxxxxxxxxxx----------
--------------------------------------------------
------LFVSILLVLLSGFIEKNTWSGLEDFHTSLTKALQVECDSGIGLG
VKKKVRRRRRGLAGITPAEAARPIIGLVEGDGRTLSEMLSWGVMAILVFL
VCLNALLYYKLWVLEEWTQNSSHSFTVMDLQVLRF---------------
-----SGALLHRDGSxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
--------------------------------------------------
--------------------------xx----------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-------------------------------------------------T
PPKSQDEWLRLLQQQEALHNVEMQKWQKVLQAAVQLLRQTEESLSELQVS
IHPLVSKKVLSVLKDTFAEEAAAAxALRGESPAEDVVMTETSREEL
>Tce
x-------------------------------------------------
-----------------------------------------------xx-
---------xxxxxxxxxxxxxxxxxxxxKNKHEDNVSRSSDSGGPPVLE
LSRSLxxxxxKDxxExxxxxxRSKKKSSWYNALYPTYKSRSEDFRRIFKD
VPPEERLVV-----------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------------------------DYSxxxQKD
ILVHGRLYVxQNYLCFYANIFRWxxx------------------------
-----VSLKWKDVTAITKEKTALVIPNAVLVxTETDKLFFTSFGARDKTY
LxxxxxxQ--NALMxxVTTFWLxxxxxSMQEMWQWVHSCYGEELGLTSDD
EDYIHPVLEEDKISNIGVPLSVDSFVEEFTESPLELPVDCHLDDSLPGLL
YRHQQVSPHSPGKRVPGIASISLLSENLPTDMSDTTDSDADKHxGEFYTF
VSLETHWKVSKSDLSRGSKTEMVRACSEDVGGRNPKRNDEDEEKDRKEAK
KEMRGANNIYASERRRIETCKxxxxxxxVCSxQHEG-----------RKI
VRSIFPVHIDQLFTLLFTSSKFFLDFHTIRRTS-----------------
--------------------------------------------------
--------D---------MNLSPWQQSPDSGLKQRVVTLTMPLSQSVGPK
STHVCET------------------------------------Q------
--------------------------------------------------
---IMLPCSKPGQLYAIDSDSVNSGIPYADSFYVTTHYCISRTGENECCL
AVYCQIKYKKNV------------------------xxxx----------
--------------------------------------------------
------LFVSLLLGLLSGFIEKNTWSGLEDFHTSLTKALQVECDSGIxLG
VKKKVRRRRRGLAGITPAEVARPIIGLVEGDGRTLSEMLSWGVMAILVFL
VCLNALLYYKLWVLEEWTQNSSHSFTVMDLQVLRYxxxx-----------
-----x------------xxxxxxxxxxxxxxxxxxGSxxHSxxxxxxxx
--------------------------------------------------
--------------------------xxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxx------------------------xxxxxxxx---------
-----------------------------xxxxxxxxxxxxxxxxxxxx-
-------xxxGTxLHSxxxxxxxx-------xxxxxxxxxxxx-------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------------------------------xxxxx---
------------------------------------xxxxxxxx------
----------xxxxxxxxx-------------------------------
-------------------------------------------------T
PPKSQDEWLRLLQQQEALHNVEMQKWQKVLQAAVQLLRQTEESLSELQVS
IHPLVSKKVLSVLKDTFAEEAAAAxALRGELPAEDVVTTETSREEL
>Tdi
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
----------------------------------EG-----------RKI
VRSVFPVHIDQLFTLLFTSSKFFLDFHTIRRTS-----------------
--------------------------------------------------
--------D---------MNLSPWQQSPDTGLKQRVVTLTMPLSQSVGPK
STHVCETx-------------------------xxxxxxxLSVQ------
--------------------------------------------------
---IMLPCSKPGQLYAIDSDSVNSGIPYADSFYVTTHYCISRTGENECCL
AVYCQIKYKKNVWGIVK-----------x---------------------
--------------------------------------------------
------------------FIEKNTWSGLEDFHTSLTKALQVECDSGIGLG
VKKKVRRRRRGLAGITPAEAARPIIGLVEGDGRTLSEMLSWGVMAILVFL
VCLNALLYYKLWVLEEWTQNSSHSFTVMDLQVLRYxxxxxLVRYYxxxxx
xxxxxSGALLHRDGSxxxxxxxxxxxxxxxxxYVPxGSLVHSxxxxxxxx
xxxxGTLLHRDGxxxxxxxxxxxxxxQVLRYxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxx------------------------xxxxxxxxxxxxxxxxx
xxxxxxxxx----------xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-
-------xxSGTFLRRDGSxxxQVxxxxxSSHSFTxxxxxxxx-------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------------------------------xxxxx---
------------------------------------xxxxxxxx------
--------------------------------------------------
------------------------------------------xxxxxxRT
PPKSQDEWLRLLQQQEALHNVEMQKWQKVLQAAVQLLRQTEESLSELQVS
IHPLVSKKVLSVLKDTFAEEAAAAxALRGESPAEDVVMTETSREEL
>Tsi
x-------------------------------------------------
-----------------------------------------------x--
--xxxxxx------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-------------------------VQEFTESPLELPVDCHLDDTLPGLL
YRHQQVSPHSPGKRVPGIASINLLSESLPTDMSDTTDSDADxx-------
--------------------------------------------------
---------------------x----------------------------
--------------------------------------------------
--------------------------------------------------
--------D---------MNLSPWQQSPDTGLKQRVVTLTMPLSQSVGPK
STHVCETxxxxxxxxxxxxxxxxxxxxxxxxxxx--xxxxLSVQ------
--------------------------------------------------
---IMLPCSKPGQLYAIDSDSVNSGIPYADSFYVTTHYCISRTGENECCL
AVYCQIKYKKNVWGIVK---------------------------------
--------------------------------------------------
-----------------SFIEKNTWSGLEDFHTSLTKALQVECDSGIGLG
VKKKVRRRRRGLVGITPAEAARPIIGLVEGDGRTLSEMLSWGVMAILVFL
VCLNALLYYKLWVLEEWTQNSSHSFTVMDLQVLRS---------------
-----SGTFLHRDGS--------------------xxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxx--------------------xxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxx--------------------x
xTFLHRDGS------------------------Txxxxxxxxxxxxxxxx
--xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxSGTFLHRDGxxxxxx-------RSFTVMDLQVLxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxDRMKxxxxxxxxxxxxxxxxxxxxxxxx
xQCKDxxxxxRRVVEAxxxxxxxAQCGNAEVAESAAGCxxxxQTGNNCPS
SGVQHLxxxxxxxxxxxxFLFFASxxxxxLxxxxxCTSNRGCxxxxxxFL
xxxxxxxxxIYRxxxxxxxxxxxxxxxxxxxxxxxYCSGRGxxxxLSSYL
STxxxSSSFNVSASVGCLAHPxxxxxxxPNFSLxxxxxxxxxSLHVHLVR
GLPQPHxxxxxx-----------------------xxxxxxxxxxxxxxx
xxxxxxxx----------------------------------------xx
xx-------------------------------------TEESLSELQVS
IHPLVSKKVLSVLKDTFAEEAAAAxALRGESPAEDVVMTETSREEL
>Tcm
xx--xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxT
ILMTIPILxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-----xx-
---------------------------------xxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxSWxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxx-----------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------------------------xxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxSxPxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxx--xxxxxQ----------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
----------------------------------------------