>Tge -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----xxxHExxxxKxxxxxSKxxxxxxxxLPSxxITKAGEAFxxxVxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxx---------------------------- ----------------------xxx------------------------- -QVGLKELETGYKLNRSIRQILCVMTLLSYHLIVVHILSHMEGNLEFCDE ILRSQLQMYPDGVWFLFFKGRLEFMKGNIEDSINWYVRSWKSQDMWPQFH HLCFWELMWTNSVKCEWREASTYASRLLEESRWSRTIYSYQRAAFLSML- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ---------------------------EKTEYDADNRGLVLLLKGVSLRH MHSPLQAEECLKTVISLEKKLKEDNYLVPYALVELAFIYKEQGNVSKASQ ILEEAK-------------KNYxx-------------------------- ---xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ------------------------- >Tms MxxLExExxxxDACESQPI------------------------------- --PSSMDLDVAMEEARAAVNFFFNNKFDEAKDILKPWADTSMYHAVGHSV FLFLEAMLTFEAQHIEAASEALRQCVAVCNKYRKKNTITESLGKIVKKAN YDHxxx--------------------------xxx--------------- ----------------------------------------xxxxxxxxAL Lxxxxxx------------------------------------------- -------------------------------------------------- ---------------------xxxxxxxxxxxxxxxxxRMCYNSYKECMT ILNSRQWHNENHKVHFESGVRMGIGAFNLMISLLPARAIRLLEFIGFSGS KQVGLKELETGYKLNRSIRQILCVMTLLSYHLIVVHILSHMEGNLEFCDE ILRSQLQMYPDGVWFLFFKGRLEFMKGNIEDSINWYVRSWKSQDMWPQFH HLCFWELMWTNSVKCEWREASTYASRLLEESRWSRTIYSYQRAAFLSMLG DDIEAEEKTEIGNLMR---------------------------------- -------------------------------------------------- -------------------------------------------------- ---NxxxxxxxxxxxxxxxxxxxxxxASRFFSQGNYLLLPALELLYVWNL FKVLGKKKQLMYNVYKIIxxALLNLNEQ---------------------- --------------------------EEKTEYDADNRGLVLLLKGVSLRH LHSPLQAEECLKTVISLEKKLKEDNYLVPYALVELAFIYKEQGNVSKAYQ ILEEAK-------------KNYxx-------------------------- ---xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ------------------------- >Tpa -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----xxx------------------------------------------- -------------------------------------------------- ---------------------xxxxxxxxxxxxxxxxxRMCYNSYKECMT ILNSRRWQNENHKVHFESGVRMGIGAFNLMISLLPARAIRLLEFIGFSGS KQVGLKELETGYKLNRSIRQILCVMTLLSYHLIVVHILSHMEGNLEFCDE ILRSQLQMYPDGVWFLFFKGRLEFMKGNIEDSINWYVRSWKSQDMWPQFH HLCFWELMWTNSVKCEWREASTYASRLLEESRWSRTIYSYQRAAFLSMLG DDIEEEEKTEIGNLMR---------------------------------- -------------------------------------------------- -------------------------------------------------- ---NxxxxxxxxxxxxxxxxxxxxxxASRFFSQGNYLLLPALELLYVWNL FKVLGKKKQLVYNVYKIIxxALLDLNEQ---------------------- --------------------------EEKTEYDADNRGLVLLLKGVSLRH MHSPLQAEECLKTVISLEKKLKEDNYLVPYALVELAFIYKEQGNVSKASQ ILEEAK-------------KNYxx-------------------------- ---xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ------------------------- >Tps -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ------------------xxxxxxxxASRYFSQxxxxxxxxxxLLYVWNx xxxxxxxxQxVYNVYKIIxxALLNLNEQ---------------------- --------------------------EEKTEYDADNRGLVLLLKGVSLRH LHSPLQAEECLKTVISLEKKLKEDNYLVPYALVELAFIYKEQGNVSKAYQ ILEEAK-------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ------------------------- >Tcm -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----xxx------------------------------------------- -------------------------------------------------- ---------------------xxxxxxxxxxxxxxxxxRMCYNSYKECMT ILNSRQWHNENHKIHFESGVRMGIGAFNLMISLLPARAIRLLEFIGFSGS KQVGLKELETGYKLNRSIRQILCVMTLLSYHLIVVHILSHMEGNLEFCDE ILRSQLQMYPDGVWFLFFKGRLEFMKGNIEDSITWYVRSWKSQDMWPQFH HLCFWELMWTNSVKCEWREASTYASRLLEESRWSRTIYSYQRAAFLSMLG DDIEAEEKTEIGNLMR---------------------------------- -------------------------------------------------- -------------------------------------------------- ---NxxxxxxxxxxxxxxxxxxxxxxASRYFSQGNYLLLPALELLYVWNL FKVLGKKKQLVYNVYKIIxxALxxLNxQ---------------------- --------------------------EEKTEYDADNRGLVLLLKGVSLRH LHSPLQAEECLKTVISLEKKLKEDNYLVPYALVELAFIYKEQGNVSKAYQ ILEEAK-------------KNYxx-------------------------- ---xxxxxxxxxxxxxxxxxxxxxx----------xxxxxxxxxxxxx-- ---------xx--------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----xx------------------------------------------- -------------------------------------------------- ------------------------x >Tce xxx-----------xxxPAPYDPPPWKQERWVMxxxxxxSRWRKAAALQP SGPSSMDLDVAMEEARAAVNFFFNNKFDEAKDILKPWADTSMYHAVGHSV FLFLEAMLTFEAQHIEAASEALRxCVAxxxKYRKKNTITESLGKIVKKAN YDHxxxxxxxxxxxxxxxxxxxxxxxRLRIPGL----------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ---------------------------------------------RECMT ILNSRQWHNENHKVHFESGVRMGIGAFNL--------------------- -QVGLKELETGYKLNRSIRQILCVMTLLSYHLIVVHILSHMEGNLEFCDE ILRSQLQMYPDGVWFLFFKGRLEFMKGNIEDSINWYVRSWKSQDMWPQFH HLCFWELMWTNSVKCEWREASTYASRLLEESRWSRTIYSYQRAAFLSMLG DDIEAEEKTEIGNLMRCxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxEGYKExxxxxxxxxxxxAT DGLExxDCGAVQAVGRVVGAAGASAAExxxxxxxxxxxxxxxxxxxxxxx xxLI---------------------------------------------- -------------------------------------------------- ---------------------------KKTEYDADNRGLVLLLKGVSLRH LHSPLQAEECLKTVISLEKKLKEDNYLVPYALVELAFIYKEQGNVSKAYQ ILEEAK-------------RNF---------------------------- -------------------------------------------------- ----------xxxxxxxxEDExxxxxxxxxxxxx-----------xxxx- ----------xLxxMTR--------------------------------- -------------------------------------------------- -------------------------------------------------- --------xxxxxxxxx--------------------------------- -------------------------------------------------- --------------------------xxxxxSxxxxx------------- -------------------------------------------------- -------------------------------------------------- ---------------------------xxxxx-------xxxxxxxMMMW PNQGKK-------------------------------------------- -------------------------------------------------- ------------------------- >Tdi -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------xxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx--------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ------QMYPDGVWFLFFKGRLEFMKGNIEDSITWYVRSWKSQDMWPQFH HLCFWELMWTNSVKCEWREASTYASRLLEESRWSRTIYSYQRAAFLSMLG DDIEAEEKTEIENLM----------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- --------------------------xxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxHEKTEYDADNRGLVLLLKGVSLRH LHSPLQAEECLKTVISLEKKLKEDNYLVPYALVELAFIYKEQGNVSKAYQ ILEEAK-------------------------------------------- -----------------------------------x---xx--------- --------------------------------xxxxxxxxxxxxxxx--- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ------------------------- >Tsi x--------------------------------------------xxxxx xxxx---------------------------------------------- --------------------------xxxxxxxxxxxxxxx--------- ------xxxxxxxxxx---------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- --------xxxxxxxxx--------------------------------- ----------SRVKCEWREASTYASRLLEESRWSRTIYSYQRAAFLSMLG DDIEAEEKTEIGNLM----------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- 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