>Tge
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----MEAVPRLPMISFDLKVSPEPTSFGSKLKQYIQDFYHEDAASYFTE
IRNLEGLRATAVSPARGATLASCSTLKRYYY-------------------
-------------------------------IRFEMVSVLYNIGAVHSYA
GASESREIADGMKLACTHFQCAAWAFQHLKDTFPQPSGVDLAPDIMQFMY
HLMLAQAQECILEKSMMDNRKATIIxxxxxxxxxxxxxxxxxxxxxxxxx
Cxxxxxxxxxxxx-------------------------------------
-----------------------------------------NWKRYVKFK
IAYHTCVSLLYQGQQAEEQQKMGERVAFYQAAAEKLEEANKLSKGMDNAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEVPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDEKDQ
SLFTYMTSLQLEHLNLFSEPERLPQ-------------------------
---------ELIDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNL---------------------PPADDSSRKEMQHLVNKV
EEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERY-
-----------VTFIEQNLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLIASYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCRVQE
EEREQILLKNKKSLPRTRKATSNTSSDSDSNEPSSSGPKLKDYLQNMKKG
GS--GGGGYSVGSQPSNPYFNAAVTGYGHLPSSISPQPSGYYDQSGMVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMAFKQPVDDGKFQP
HSHGPYQMPSSDNTGTKAGASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSGQYGMQQYSQGQVLPAASESSMPTSGSYYHDPSQA
TATSQANYASYTAPANTQQYNSTYSQQGGAPQYSSGTESYTGQSYSQGYT
PVAQGYPTSSMPKDATSYPSYPTSTSQAASSYLPTQQSYYPPAA------
--------------xxxDASSYTATQQSAYPSSSAEQISDTYSSYAYTSP
SVMGGSYQVSTQQPGASFSTPSYTGGSTTDTGVSYSQYMQQSQYYPGVQV
PKPGLSQTSSYGGHPGYSFNTTSGTYSYGSGYQSSSAEENNYNVGEYQQG
NQQVSVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQP-SYYQYDYSTQPTDVATVLHTSSVAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQAESYQTPEYVQNQYYTVQYGYQ
NASGMPNMDTPPQSPRHIIVQQQGG-------------------------
--------------------------------------------------
---PAKAKLVESPIKQAVVTQAVTVPTSFSPKKSPLNSVPLPKLSPPLEQ
STSVPNLKPQETNSSEKQNGDISNIMVPPSEGNKESKLTLKVFGKDLYTD
PEALNQFVQEVEKYEKFVEGLTTKTLNGPTPLDMKWKELLDFQ-------
--------------------------------------------------
-------------DVTPLTPPFIVTQAPLPSTYCDFWTMVWEQQVEVVVC
LLSDSELNNQVYWPLEKGQELAMGKMKLSLQSSNVRPHWTERILSICVGE
TRVSRVIVHLQFTAWPGSSFPASPGPFLSLVCEALTFYCQQRAASHPVVV
HCLSGVGRTGLFVLATAAVCEVQAGQGLLDLVPTASTMSASRKNSLRDRE
HLKFAYQAVLYYAQDFLMKRGILTSRSTFEDKRSRAGKSHTRHPSEDFLL
GPPTDLSQLQSGVEKMG---------------------------------
-----------------------LAAANNNDSLTTLPRYRCDGVANSHPE
GQLVGSNSGSVSNSRSSTPPFGYLPSLADPSKFSLKTEAPQEKSRKRFTR
ESFEAKRRESTTSLESSQINTDDPISLIDPLWPLKRL
>Tms
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----MEAVPRLPMISFDLKVSPEPTSFGSKLKQYIQDFYHEDATSYSTE
IRNLEGLRATAVSPVRGATLASCSTLKRYYCQLHFLQSRFPMAKDGAAA-
-------------VPFTWRDTYANMVCTLADIRFEMVSILYNIGAVHSYA
GASESRETADGMKLACTHFQCAAWAFQHLKDTFPQPSGVDLAPDIMQFMY
HLMLAQAQECILEKSMMDNRKATIIxxxxxxxxxxxxxxxxxxxxxxxxx
Cxxxxxxxxxxxx-------------------------------------
-----------------------------------------NWKRYVKFK
IAYHTCVSLLYQGQQAEEQQKMGERVAFYQAAAEKLEEANKLSKGMDSAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEVPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDDKDQ
SLFTYMTSLQLEHLNLFSEPERLPQ-------------------------
---------ELVDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNLRILSLPLDExxSQIPSLKVLDSPADDSSRKEMQHLVNKV
EEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERY-
-----------VTFIEQNLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLISSYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCKVQE
EEREQILLKNKKSLPRTRKATSNTSSDSESNEPSSSGPKLKDYLQNMKKG
GSxxGGGGYSVGSQPSNPYFNAAVTGYGHLPSSISPQPSGYYDQSGMVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMASKQPVDDGKLQP
HSHGSYQMPTSDSTGIK--ASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSDQYGMQQYSQGQVLPAASESSMPTSGSYYHDPSQA
TATSQANYAAYTAPANTQQYNLTYSQQGGAPQYSSGTESYTGQSYNQGYT
PVAQGYPTSSTPKGA-SYPSYPTSTSQTASSYFPTQQSYYPPAAxxxxAA
LYHSTQKLPYSSTFTSQDASSYTATQQSAYPSSSAEQISDNNSSYAYTSP
SAMGGSNQVSTQQPGASFATPSYTEGSTTDTGVSYSQYMPQSQYYPGVQV
PKPGLSQTSSYGGHPGYSFNTTSGTYNYGSGYQSSSAEENNYNTGEYQQG
NQQVSVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQP-SYYQYDYSAQPTDVATVLHNSSIAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQAESYQTPEYIQNQYYTVQYGYQ
NASGMPNMDTPPQSPHHVVVQQQGGxNSQQQNPQQQSAVNPMTYMQAGDP
NSTTTTYSQKGASPYSSSTSAEGAEGSTEPSSNLDLLAGLDFSVNQAPLV
PQQPTKANLVESPVKQTVVTQAVTAPTSFSPKKSSQNSVSSPKLSPPLEQ
LASVTNLKPQETNSSEKHNGDISNLMVPPSDGNKESKLTLKVFGKDLYTD
PEALNQFVQEVEKFEKFVEGLTTKTLNGPTPLDMKWKELLDFQ-------
--------------------------------------------------
-------------DVTPLTPPFIVTQAPLPSTYCDFWTMVWEQQVEVVVC
LLSDSELNNQVYWPLEKGQELAMGKMKLSLQSSNVRPHWTERILSICVGE
TRVSRVIVHLQFTAWPGSSFPASPGPFLSLVCEALTFYCQQRAASHPVVV
HCLSGVGRTGLFVLATAAVCEVQAGQGLLDLVPTASTMSASRKNSLRDRE
HLKFAYQAVLYYAQDLLMKRGILTSRSTFEDKRSRAGKSHTRHPSEDFLL
GPPTDLSQLQSGVEKMG---------------------------------
-----------------------LAATNNSDSLTTLPRYRCDDGADSHPA
GQLVGSNSGSVSNSRSSTPPFGYLPNLADPSKFNLKTEAAQDKSRKRFTR
ESFESKRRVSTTSLESSQIDTDDPLSLIDPLWPLKRL
>Tsi
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----MEAVPRLPMISFDLKVSPEPTSFGSKLKQYIQDFYHEDATSYLTE
IRNLEGLRATAVSPARGATLASCSTLKRYYCQLHFLQSRFPMAKDGAAA-
-------------VPFTWRDTYANMVCTLADIRFEMVSILYNIGAVHSYA
GASESRETADGMKLACTHFQCAAWAFQHLKDTFPQPSGVDLAPDIMQFMY
HLMLAQAQECILEKSMMDNRKATII-------------------------
--------------------------------------------------
--------------------------------------------------
------------GQQAEEQQKMGERVAFYQAAAEKLEEANKLSKGMDSAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEIPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDDKDQ
SLFTYMTSLQLEHLNLFSEPERLPQ-------------------------
---------ELVDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNLRILSLPLDExxSQIPSLKVLDSPADDSSRKEMQHLVNKV
EEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERY-
-----------VTFIEQNLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLISSYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCKVQE
EEREQILLKNKKSLPRTRKATSNTSSDSESNEPSSSGPKLKDYLQNMKKG
GS-xxGGGYSVGSQPSNPYFNAAVTGYGHLPSSISPQPSGYYDQSGIVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMASKQPVDDGKLQP
HSHGSYQMPTSDSTGMKAGASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSDQYGMQQYAQGQVLPAASESSLPTSGSYYHDPSQS
TATSQANYAAYAAPANTQQYNSTYSQQGGAPQYSSGTESYTGQSYSQGYT
PVAQGYPTSSTPKGA-SYPSYPTSTSQTASSYFPTQQSYYPLAAxxxDAA
LYHSTQKLPYSSTFTSLDASSYTATQQSAYPSSSAEQISDNNSSYPYTSP
SAMGGSNQVSTQQPGASFSTPSYTEGSTTDTGVSYSQYMPQSQYYPGVQV
PKPGPSQTSSYGGHPGYSFNTTSGTYNYGSGYQSSSAEENNYNVGEYQQG
NQQGSVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQP-SYYQYDYSAQPTDVATVLHTSSIAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQAESYQTPEYIQNQYYTVQYGYQ
NASGMPNMDTPPQSPHHVIVQQQGGVNSQQQNPQQQSAVNPMTYMQAGDP
NSTTITYSQKGASPYSSSTSAEGAETSTEPSSNLDLLAGLDFSVNQAPLV
PQQPAKENLVESPIKQTVVTQAVTPPTSFSPKKSIQNSVSSPKLSPPLEQ
STSVTNLKPQETNSSEKHNGDISNLMVPPSDGNKESKLTLKVFGKDLYTD
PEALNQFVQEVEKFEKFVEGLTTKTLNGPTPLDMKWKELLDFQLANALVV
LSSTAEDGEIEVRISEKDAHKHSISVARCYPMKNRFPDILPYDNSRVELP
STKDDYINASFMKDVTPLTPPFIVTQAPLPSTYCDFWTMVWEQQVEVVVC
LLSDSELNNQVYWPLEKGQELAMGKMKLSLQSSNVRPHWTERILSICVGE
TRVSRVIVHLQFTAWPGSSFPASPGPFLSLVCEALTFYCQQRAASHPVVV
HCLSGVGRTGLFVLATAAVCEVQAGQGLLDLVPTASTMSASRKNSLRDRE
HLKFAYQAVLYYAQDLLMKRGILTSRSTFEDKRSRAGKSHTRHPSEDFLL
GPPTDLSQLQSGVEKMG---------------------------------
-----------------------LAATNNSDSLTTLPGYRCDGGADSHPA
GQLVGSNSGSVSNSRSSTPPFGYLPSLADPSKFSLKTEAAQDKSRKRFTR
ESFESKRRESTTSLDSSQIDTDDPLSLIDPLWPLKRL
>Tcm
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----MEAVPRLPMISFDLKVSPEPTSFGSKLKQYIQDFYHEDATSYLTE
IRNLEGLRATAVSPARGATLASCSTLKRYYCQLHFLQSRFPMAKDGAAA-
-------------VPFTWRDTYANMVCTLADIRFEMVSILYNIGAVHSYA
GASESRETADGMKLACTHFQCAAWAFQHLKDTFPQPSGVDLAPDIMQFMY
HLMLAQAQECILEKSMMDNRKATII-------------------------
--------------------------------------------------
--------------------------------------------------
------------GQQAEEQQKMGERVAFYQAAAEKLEEANKLSKGMDSAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEIPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDDKDQ
SLFTYMTSLQLEHLNLFSEPERLPQ-------------------------
---------ELVDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNLRILSLPLDExxSQIPSLKVLDS--DDSSRKEMQHLVNKV
EEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERY-
-----------VTFIEQNLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLISSYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCKVQE
EEREQILLKNKKSLPRTRKATSNTSSDSESNEPSSSGPKLKDYLQNMKKG
GS-xxGGGYSVGSQPSNPYFNAAVTGYGHLPSSISPQPSGYYDQSGMVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMASKQPVDDGKLQP
HSHGSYQMPTSDSTGMKAGASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSDQYGMQQYAQGQVLPAASESSLPTSGSYYHDPSQS
TATSQANYAAYAAPANTQQYNSTYSQQGGAPQYSSGTESYTGQSYSQGYT
PVAQGYPTSSTPKGA-SYPSYPTSTSQTASSYFPTQQSYYPLAAxxxDAA
LYHSTQKLPYSSTFTSQDASSYTATQQSAYPSSSAEQISDNNSSYPYTSP
SAMGGSNQVSTQQPGASFSTPSYTEGSTTDTGVSYSQYMPQSQYYPGVQV
PKPGLSQTSSYGGHPGYSFNTTSGTYNYGSGYQSSSAEENNYNVGEYQQG
NQQGSVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQP-SYYQYDYSAQPTDVATVLHTSSIAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQAESYQTPEYIQNQYYTVQYGYQ
NASGMPNMDTPPQSPHHVIVQQQGGVNSQQQNPQQQSAVNPMTYMQAGDP
NSTTITYSQKGASPYSSSTSAEGAESSTEPSSNLDLLAGLDFSVNQAPLV
PQQPAKEILVESPIKQTVVTQAVTPPTSFSPKKSLQNSVSSPKLSPPLEQ
STSVTNLKPQETNSSEKHNGDISNLMVPPSDGNKESKLTLKVFGKDLYTD
PEALNQFVQEVEKFEKFVEGLTTKTLNGPTPLDMKWKELLDFQ-------
---------------EKDAHKHSISVARCYPMKNRFPDILPYDNSRVELP
STKDDYINASFMKDVTPLTPPFIVTQAPLPSTYCDFWTMVWEQQVEVVVC
LLSDSELNNQVYWPLEKGQELAMGKMKLSLQSSNVRPHWTERILSICVGE
TRVSRVIVHLQFTAWPGSSFPASPGPFLSLVCEALTFYCQQRAASHPVVV
HCLSGVGRTGLFVLATAAVCEVQAGQGLLDLVPTASTMSASRKNSLRDRE
HLKFAYQAVLYYAQDLLMKRGILTSRSTFEDKRSRAGKSHTRHPSEDFLL
GPPTDLSQLQSGVEKMG---------------------------------
-----------------------LAATNNSDSLTTLPGYRCDGGADSHPA
GQLVGSNSGSVSNSRSSTPPFGYLPSLADPSKFSLKTEAAQDKSRKRFTR
ESFESKRRESTTSLDSSQIDTDDPLSLIDPLWPLKRL
>Tps
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----MEAVPRLPMISFDLKVSPEPTSFGSKLKQYIQDFYHEDATSYLTE
IRNLEGLRATAVSPVRGATLASCSTLKRYYCQLHFLQSRFPMSKDGAAA-
-------------VPFTWRDTYANMVCTLADIRFEMVSILYNIGAVHSYA
GASESRETADGMKLACTHFQCAAWAFQHLKDTFPQPSGVDLAPDIMQFMY
HLMLAQAQECILEKSMMDNRKATIIxx-----------------------
------------xxx---------------xxxxxx--------------
-----------------------------------------NWKRYVKFK
IAYHTCVSLLYQGQQAEEQQKMGERVAFYQAAAEKLEEANKLSKGMDSAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEIPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDDKDQ
SLFTYMTSLQLEHLNLFSEPERLPQ-------------------------
---------ELVDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNLRILSLPLDExxSQIPSLKVLDSPADDSSRKEMQHLVNKV
EEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERY-
-----------VTFIEQNLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLISSYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCKVQE
EEREQILLKNKKSLPRTRKATSNTSSDSESNEPSSSGPKLKDYLQNMKKG
GS-xxGGGYSAGSQPSNPYFNAAVTNYGHLPSSISPQPSGYYDQSGMVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMASKQPVVDGKLQP
HSHGSYQMPTSDSTGMKAGASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSDQYGMQQYSQGQVLPAASESSLPTSGSYYHDPSQS
TATSQANYAAYAAPANTQQYNSTYSQQGGAPQYSSGTESYTGQSYSQGYT
PVAQGYPTSSTPKGA-SYPSYPTSTSQTASSYFPTQQSYYPLAAxxxDAA
LYHSTQKLPYSSTFTSQDASSYTATQQSAYPSSSAEQISDNNSSYAYTSP
SAMGGSNHVSTQQPGASFSTPSYTEGSTTDTGVSYSQYMPQSQYYPGVQV
PKPGLSQTSSYGGHPGYSFNTTSGTYNYGSGYQSSSAEENNYNLGEYQQG
NQQASVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQP-SYYQYDYPAQPTDVATVLHTSSIAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQAESYQTPEYIQNQYYTVQYGYQ
NASGMPNMDTPPQSPHHVIVQQQGNVNSQQQNPQQQSAVNPMTYMQAGDP
NSTTTTYSQKGASPYSSSTSAEGAESSTEPSSNLDLLAGLDFSVNQAPLV
PQQPAKANLVESPVKQTVVTQAVTAPTSFSPKKSSQNSVSSPKLSPPLEQ
STSVTDLKPQETNSSEKHNGDISNLMVSPSDGNKESKLTLKVFGKDLYTD
PEALNQFVQEVEKFEKFVEGLTTKTLNGPTPLDMKWKELLDFQ-------
---------------EKDAHKHSISVARCYPMKNRFPDILPYDNSRVELP
STKDDYINASFMKDVTPLTPPFIVTQAPLPSTYCDFWTMVWEQQVEVVVC
LLSDLELNNQVYWPLEKGQELAMGKMKLSLQSSNVRPHWTERILSICVGE
TRVSRVIVHLQFTAWPGSSFPASPGPFLSLVCEALTFYCQQRAASHPVVV
HCLSGVGRTGLFVLATAAVCEVQAGQGLLDLVPTASTMSASRKNSLRDRE
HLKFAYQAVLYYAQDLLMKRGILTSRSTFEDKRSRAGKSHTRHPSEDFLL
GPPTDLSQLQSGVEKMG---------------------------------
-----------------------LAATNNSDSLTTLPGYRCDSGADSHPA
GQLVGSNSGSVSNSRSSTPPFGYLPSLADPSKFSLKTEAAQDKSRKRFTR
ESFESKRRESTTSLESSQIDTDDPLSLIDPLWPLKRL
>Tdi
MPQQGTQLVTAGGQNLAYNVMQPMQTVTIDGQEALFIPAMPATQPQAMQT
LITPSGQIIRTPGIFPTSLLQNVGGQTVQMANGQNVTVRPANIPQMVQFP
MQQTIPVQVPISTSNGQTVYQTFHFPAQAFATAIPNIVQASANNQVQMIP
QLSQTVAAPTLVGSGGNSDSSGPHHVTIQGQGQAGQSVILGQSQQLTLTN
AQGQQIVIPANSLTNLGQATTMRTGGNIIQLPNLTNLQTIPVQNIPGLGN
VQLIPASALSIGTQVQLGLSPSGTSVSQSSGTPTITTMPPGAQIIATGQH
LQQRNPCDYYQSHQQDPNEPLKWQVITTSNQVNNGQSQTQNISGSMNSTT
NSDSGDSPAKARVRRVACCCPNCIDGERNGDRKRQHICHIPGCNKVYGKT
SHLRAHLRWHTGERPFICSWLFCGKRFTRSDELQPCSALHRMSDDDGTKL
VIFIIAFIISTSVHLAVILTTMMITNLFVFQASTIAGHPKTCAVIGSFKR
HRRTHTGEKRFQCPECSKKFMRSDHLSKHIKTHTKLRNSVSGLTGVTAFD
GWMELVMLLEKGYFESVSSVREPWMNDGLYKIQIPQQQSDSDETITETDD
IEGIQKFGYQMADSRNEAATSTQDVSSDGSSSNDEKMMITIQTEADQSDL
TIIDEMEAVPRLPMISFDLKVSPEPTSFGSKLKQYIQDFYHEDATSYLTE
IRNLEGLRATAVSPVRGATLASCSTLKRYYCQLHFLQSRFPMSKDGAAAx
xxxxPLLPSMSxx-----RDTYANMVCTLADIRFEMVSILYNIGAVHSYA
GASESRETADGMKLACTHFQCAAWAFQHLKDTFPQPSGVDLAPDIMQFMY
HLMLAQAQECILEKSMMDNRKATII-------------------------
-----------------------------------xxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxYRDVICYVxxxxxxxxxxxxNWKRYVKFK
IAYHTCVSLLYQGQQAEEQQKMGERVAFYQAAAEKLEEANKLSKGMDSAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEIPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDDKDQ
SLFTYMTSLQLEHLNLFSEPERLPQ-------------------------
---------ELVDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNLRILSLPLDE----------LDTPADDSSRKEMQHLVNKV
EEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERY-
-----------VTFIEQNLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLISSYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCKVQE
EEREQILLKNKKSLPRTRKATSNTSSDSESNEPSSSGPKLKDYLQNMKKG
GS-xxGGGYSAGSQPSNPYFNAAVTNYGHLPSSISPQPSGYYDQSGMVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMASKQPVVDGKLQP
HSHGSYQMPTSDSTGMKAGASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSDQYGMQQYSQGQVLPAASESSLPTSGSYYHDPSQS
TATSQANYAAYAAPANTQQYNSTYSQQGGAPQYSSGTESYTGQSYSQGYT
PVAQGYPTSSTPKGA-SYPSYPTSTSQTASSYFPTQQSYYPLAAxxxDAA
LYHSTQKLPYSSTFTSQDASSYTATQQSAYPSSSAEQISDNNSSYAYTSP
SAMGGSNHVSTQQPGASFSTPSYTEGSTTDTGVSYSQYMPQSQYYPGVQV
PKPGLSQTSSYGGHPGYSFNTTSGTYNYGSGYQSSSAEENNYNLGEYQQG
NQQASVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQP-SYYQYDYPAQPTDVATVLHTSSIAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQAESYQTPEYIQNQYYTVQYGYQ
NASGMPNMDTPPQSPHHVIVQQQGDVNSQQQNPQQQSAVNPMTYMQAGDP
NSTTTTYSQKGASPYSSSTSAEGAESSTEPSSNLDLLAGLDFSVNQAPLV
PQQPAKANLVESPVKQTVVTQAVTAPTSFSPKKSSQNSVSSPKLSPPLEQ
STSVTDLKPQETNSSEKHNGDISNLMVSPSDGNKESKLTLKVFGKDLYTD
PEALNQFVQEVEKFEKFVEGLTTKTLNGPTPLDMKWKELLDFQ-------
---------------EKDAHKHSISVARCYPMKNRFPDILPYDNSRVELP
STKDDYINASFMKDVTPLTPPFIVTQAPLPSTYCDFWTMVWEQQVEVVVC
LLSDSELNNQVYWPLEKGQELAMGKMKLSLQSSNVRPHWTERILSICVGE
TRVSRVIVHLQFTAWPGSSFPASPGPFLSLVCEALTFYCQQRAASHPVVV
HCLSGVGRTGLFVLATAAVCEVQAGQGLLDLVPTASTMSASRKNSLRDRE
HLKFAYQAVLYYAQDLLMKRGILTSRSTFEDKRSRAGKSHTRHPSEDFLL
GPPTDLSQLQSGVEKMG---------------------------------
-----------------------LAATNNSDSLTTLPGYRCDSGADSHPA
GQLVGSNSGSVSNSRSSTPPFGYLPSLADPSKFSLKTEAAQDKSRKRFTR
ESFESKRRESTTSLESSQIDTDDPLSLIDPLWPLKRL
>Tce
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
---------------------------------------------MDSAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEVPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDDKDQ
SLFTYMTSLQLEHLNLFSEPERLPQ-------------------------
---------ELVDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNLRILSLPLDE----------LDTPADDSSRKEMQHLVNKV
EEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERY-
-----------VTFIEQNLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLISSYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCKVQE
EEREQILLKNKKSLPRTRKATSNTSSDSESNEPSSSGPKLKDYLQNMKKG
GSxxGGGGYSVGSQPSNPYFNAAVTGYGHLPSSISPQPSGYYDQSGMVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMASKQPVDDGKLQP
HSHGSYQMPTSDSTGIK--ASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSDQYGMQQYSQGQVLPAASESSMPTSGSYYHNSSQA
TATSQANYAAYTAPANTQQYNSSYSQQGGAPQYSSGTESYTGQSYNQGYT
PVAQGYPTSSTPKGA-SYPSYPTSTSQTASSYFPTQQSYYPPAAxxxxAA
LYHSTQKLPYSSTFTSQDASSYTATQQSAYPSSSAEQISDNNSSYAYTSP
SAMGGSNQVSTQQPGASFSTPSYTEGSTTDTGVSYSQYMPQSQYYPGVQV
PKPGLSQTSSYGGHPGYSFNTTSGTYNYGSGYQSSSAEENNYNAGEYQQG
NQQVSVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQP-SYYQYDYSDQPTDVATVLHNSSIAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQVESYQTPEYIQNQYYTVQYGYQ
NASGMPNMDTPPQSPHHVVVQQQGGxNSQQQNPQQQSAVNPMTYMQAGDP
NSTTTTYSQKGSSPYSSSTSAEGAEGSTEPSSNLDLLAGLDFSVNQAPLV
PQQPAKANLVESPVKQTVVTQAVTAPTSFSPKKSSQNSVSSPKLSPPLEQ
SASVTNLKPQETNSSEKHNGDISNLMGPPSDGNKESKLTLKVFGKDLYTD
PEALNQFVQEVEKFEKFVEGLTTKTLNGPTPLDMKWKELLDFQ-------
---------------EKDAHKHSISVARCYPMKNRFPDILPYDNSRVELP
STKDDYINASFMKDVTPLTPPFIVTQAPLPSTYCDFWTMVWEQQVEVVVC
LLSDSELNNQVYWPLEKGQELAMGKMKLSLQSSNVRPHWTERILSICVGE
TRVSRVIVHLQFTAWPGSSFPASPGPFLSLVCEALTFYCQQRAASHPVVV
HCLSGVGRTGLFVLATAAVCEVQAGQGLLDLVPTASTMSASRKNSLRDRE
HLKFAYQAVLYYAQDLLMKRGILTSRSTFEDKRSRAGKSHTRHPSEDFLL
GPPTDLSQLQSGVEKMG---------------------------------
-----------------------LAATNNSDSLTTLPRYRCDHGADSHPA
GQLVGSNSGSVSNSRSSTPPFGYLPNLADPSKFNLKTEAAQDKSRKRFTR
ESFESKRRVSTTSLESSQIDTDDPLSLIDPLWPLKRL
>Tbi
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------------MVCTLADIRFEMVSVLYNIGAVHSYA
GASESRETADGMKLACTHFQCAAWAFQHLKDTFPQPSGVDLAPDIMQFMY
HLMLAQAQECILEKSMMDNRKATII-------------------------
--------------xxxxxxxxxxxxxxxxx-------------------
-----------------------------------------NWKRYVKFK
IAYHTCVSLLYQGQQAEEQQKMGERVAFYQAAAEKLEEANKLSKGMDNAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEVPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDEKDQ
SLFTYMTSLQLEHLNLFSEPERLPQ-------------------------
---------ELVDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNLRILSLPLDE----------LDTPADDSSRKEMQHLVNKV
DEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERY-
-----------VTFIEQNLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLIASYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCRVQE
EEREQILLKNKKSLPRTRKAASNTSSDSDSNEPSSSGPKLKDYLQNMKKG
GS--GGGGYSVGSQPSNPYFNAAVTGYGHLPSSISPQPSGYYDQSGMVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMAFKQPVDDGKFQP
HSHGPYQMPSSDNTGIKAGASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSGQYGMQQYSQGQVLPAASESPIPTSVSYYHDPSQA
TATSQANYASYTAPANTQQYNSTYSQQGGAPQYSSRTESYTGQSYSQGYT
PVAQGYPTSSTPKDAxSYPSYPTSTSQAASSYLPTQQSYYPPAA------
--------------TSQDASSYTATQQSAYPSSSAEQISDTYSSYAYTSP
SAMGGSYQVSTQQPGASFSTPSYTGGSTTDTGVSYSQYMQQSQYYPGVQV
PKPGLSQTSSYGGHPGYSFNTTSGTYNYGSGYQSSSAEENNYNVGEYQQG
NQQVSVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQPxSYYQYDYSTQPTDVATVLHTSSVAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQAESYQTPEYVQNQYYTVQYGYQ
NVSGMPNMDTPPQSPRHIIVQQQGG-------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------VPPSEGNKEIKLTLKVFGKDLYTD
PEALNQFVQEVEKYEKFVEGLTTKTLNGPTPLDMKWKELLDFQ-------
---------------EKDAHKHSISVARCYPMKNRFPDILPYDNSRVELP
STKDDYINASFMKDVTPLTPPFIVTQAPIPSTYCDFWTMVWEQQVEVVVC
LLSDSELNNQVYWPLEKGQELAMGKMKLSLQSSNIRPHWTERILSICVGE
TRVSRVIVHLQFTAWPGSSFPASPGPFLSLVCEALTFYCQQRAASHPVVV
HCLSGVGRTGLFVLATAAVCEVQAGQGLLDLVPTASTMSASRKNSLRDRE
HLKFAYQAVLYYAQDFLMKRGILTSRSTFEDKRSRAGKSHTRHPSEDFLL
GPPTDLSQLQSGVEKMGxxNDDYEGRVHGRVCDIACVTHPIALLETERLH
HVRH---------ISSVGSVSVYWAAANNNDSLTTLPRHRCDGVANSHPE
GQLVGSNSGSVSNSRSSTPPFGYLPSLADPSKFSLKTEAPQDKSRKRFTR
ESFEAKRRESTTSLESSQIDTDDPLSLIDSLWPLKRL
>Tte
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
------------------------MVCTLADIRFEMVSVLYNIGAVHSYA
GASESRETADGMKLACTHFQCAAWAFQHLKDTFPQPSGVDLAPDIMQFMY
HLMLAQAQECILEKSMMDNRKATII-------------------------
--------------xxxxxxxxxxxxxxxxx-------------------
-----------------------------------------NWKRYVKFK
IAYHTCVSLLYQGQQAEEQQKMGERVAFYQAAAEKLEEANKLSKGMDNAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEVPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDEKDQ
SLFTYMTSLQLEHLNLFSEPERLPQ-------------------------
---------ELVDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNLRILSLPLDE----------LDTPADDSSRKEMQHLVNKV
DEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERY-
-----------VTFIEQNLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLIASYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCRVQE
EEREQILLKNKKSLPRTRKAASNTSSDSDSNEPSSSGPKLKDYLQNMKKG
GS--GGGGYSGGSQPSNPYFNAAVTGYGHLPSSISPQPSGYYDQSGMVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMAFKQPVDDGKFQP
HSHGPYQMPSSDNTGIKAGASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSGQYGMQQYSQGQVLPAASESPIPTSVSYYHDPSQA
TATSQANYASYTAPANTQQYNSTYSQQGGAPQYSSRTESYTGQSYSQGYT
PVAQGYPTSSTPKDATSYPSYPTSTSQAASSYLPTQQSYYPPAA------
--------------xxxDASSYTATQQSAYPSSSAEQISDTYSSYAYTSP
SAMGGSYQVSTQQPGASFSTPSYTGGSTTDTGVSYSQYMQQSQYYPGIQV
PKPGLSQTSSYGGHPGYSFNTTSGTYNYGSGYQSSSAEENNYNVGEYQQG
NQQVSVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQPxSYYQYDYSTQPTDVATVLHTSSVAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQAESYQTPEYVQNQYYTVQYGYQ
NVSGMPNMDTPPQSPRHIIVQQQGG-------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------VPPSEGNKEIKLTLKVFGKDLYTD
PEALNQFVQEVEKYEKFVEGLTTKTLNGPTPLDMKWKELLDFQ-------
---------------EKDAHTHSISVARCYPMKNRFPDILPYDNSRVELP
STKDDYINASFMKDVTPLTPPFIVTQAPIPSTYCDFWTMVWEQQVEVVVC
LLSDSELNNQVYWPLEKGQELAMGKMKLSLQSSNIRPHWTERILSICVGE
TRVSRVIVHLQFTAWPGSSFPASPGPFLSLVCEALTFYCQQRAASHPVVV
HCLSGVGRTGLFVLATAAVCEVQAGQGLLDLVPTASTMSASRKNSLRDRE
HLKFAYQAVLYYAQDFLMKRGILTSRSTFEDKRSRAGKSHTRHPSEDFLL
GQPTDLSQLQSGVEKMGxxNDDYEGRVHGRVCDIACVTHPIALLETERLH
HVRH---------ISSVGSVSVYWAAANNNDSLTTLPRHRCDGVANSHPE
GQLVGSNSGSVSNSRSSTPPFGYLPSLADPSKFSLKTEAPQDKSRKRFTR
ESFEAKRRESTTSLESSQIDTDDPLSLIDSLWPLKRL
>Tpa
-------------------------xxxx---------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------xxxx-----------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------------------------NWKRYVKFK
IAYHTCVSLLYQGQQAEEQQKMGERVAFYQAAAEKLEEANKLSKGMDNAE
AINEALTFTMDVVEGKKKAAKNENEFIYHEEVPEKDTLPEVKGASLVKGI
PFDVNDPEVSGPDIFGRLVPMKAHEASSLYSEEKAKLLRKVGAMIDEKDQ
SLFTYMTSLQLEHLNLFSEPERLPQxKPPPVHPTEIRTSISPSSAVELNT
TGALANYATEAVDRCAALSAKPSAIQDLVDAMGKLADTYQDVESMLQEVK
ELLEQEEAREKEYQEVMGNRPPSIVATDLTREARKYEEAHAKASESNQTL
HKAMTMNISNLRILSLPLDExxSQIPSLKVLDSPADDSSRKEMQHLVNKV
EEMKRQRSMLATQLRDSITQDDITRQLVTRTGEPLDTIFSQEMQKHERYx
xSKSESxxxxx------NLLAQENILKALTDAYARYAGTRKATNEIIRKR
ESIINGLIASYDAYEDLLAKSSKGLEFYRKLETNVSKLLQRVKGTCRVQE
EEREQILLKNKKSLPRTRKAASNTSSDSDSNEPSSSGPKLKDYLQNMKKG
GS--GGGGYSVGSQPSNPYFNAAVTGYGHLPSSISPQPSGYYDQSGMVSQ
LSSDSGSQQWIPSVRPAPVGSEGTGEQTPSVCSSTNMAFKQPVDDGKFQP
HSHGPYQMPSSDNTGTKAGASYPLSVAYSSYNPAGYGSNTPAYRALQMPL
MHPQSAYSQGHFNYSGQYSMQQYSQGQVLPAASESPMPTSGSYYHDPSQA
TATSQANYASYTAPANTQQYNSTYSQQGGAPQYSSGTESYTGQSYSQGYT
PVAQGYPTSSTPKDATSYPSYPTSTSQAASSYLPTQQSYYPPAA------
--------------xxxDASSYTATQQSAYPSSSAEQISDTYSSYAYTSP
SAMGGSYQVSTQQPGASFSTPSYTGGSTTDTGVSYSQYMQQSQYYPGVQV
PKPGLSQTSSYGGHPGYSFNTTSGTYSYGSGYQSSSAEENNYNVGEYQQG
NQQVSVYSMTGTSSGTNPTKSNYGSEFHGNSAASSNSVTSLSSGSSSEVS
LVPQP-SYYQYDYSTQPTDVATVLHTSSVAQSTEYLYMNAGTSTSFYTNA
GTNSTSQTSSSQVSVDGQTYAAQYNTNQAESYQTPEYVQNQYYTVQYGYQ
NASGMPNMDTPPQSPRHIILQQQ---------------------------
--------------------------------------------------
---PAKAKLVESPVKQAVVTQAVTVLTSFSPKKSPLNSVPSPKLSPPLEQ
STSVPNLKPQETNSSEKQNGDISNIMVPPSEGNKESKLTLKVFGKDLYTD
PEALNQFVQEVEKYEKFVEGLTTKTLNGPTPLDMKWKELLDFQ-------
---------------EKDAHKHSISVARCYPMKNRFPDILPYDNSRVELP
STKDDYINASFMKDVTPLTPPFIVTQAPLPSTYCDFWTMVWEQQVEVVVC
LLSDSE--------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-xxxxxxxxxxxxxx-----------------------------------
--------------------------------------------------
-------------------------------------