>Tge M------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------------xYDWYGNMYAxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxNxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxLRPQPRFLDNVNKGKxxxA GGGRFxxKGKGLPRxxxxGxxxxxxGVASxxxxxxxxFFxxxxxx----- -------------------------------------------------- -------------------------------------------------- ------Gxxxxxxx------------------------------------ ----------------------xxxxxxxxxxxxxxxx----------xx TVxxxxxxxxxxxxxxxxx----xxxxxxxxxLLKWEVQERLGKARxxK- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------------------KGLD LSTPVLEREPSFENDDNVMLPLSEVWLLATSLPLLFTKPSEHHSPDNLAA GLTSHNFVTKx--------------------------------------- ----------------------------xxxxxxxxxxx----------- -------------------------------------------------- -------------------------------xxxxxxxxxxxxxxxQWAG KLPTELxxxxxFMHHVLSYRGSTLTFLRGEGGVQFCVAASTEWKESHQYW GGDDCVVIQLLPNYQIIQK------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------------GAKLLYFNLS IRGYPKGLRAGQDQRAPCLQVDEGFNLVTFCGIPYRINSVEVWGCGSQRD -------------------------------------------------- ------------------------------------------------xx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-------------------- -- >Tms xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxTxxxxLEKxAxxLVQK TSEEDHVPGISCRIFTKYVFxxYFDLAQKLYKYLLx-------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ---------------LAxxxxxxENxxxxSAFKQQxxKxLTxxxxxxxxx xxxx---------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ---------------------------------------------xxxxG xEITxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxVDSAFHRKD CLPVQYLSNWVSSHCPRLVVGLHRYVVHALTTTYRTLGKDQTxxxxVGLD LSTPVLEREPSFENDDNVMLPLSEVWLLATSLPLLFTKPSEHHSPDNLAA GLTSHNFVTKLLGSICPSHWTLLYNSNDHGLGANR--------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------FMHHVLSYRGSTLTFLRGEGGVQFCVAASTEWKESHQYW GGDDCVVIQLLPNYQIIQK------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------------GAKLLYFNLS IRGYPKGLRAGQDQRAPCLQVDEGFNLVTFCGIPYRINSVEVWGCGSQRD RxxGRVGILxxxxxxx---------------------------------- --------------------------------xxxxxxxxxxxxxxxxxP xT------------------------------------------------ -------------------------------------------------- -x >Tps 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-------------------------------------------------- -------------------------------------------------- ------------------MLPLSEVWLLATSLPLLFTKPSEHHSPDNLAA GLTSHNFVTKLLGSICPSHWTLLYNSNDHGLGANR--------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------FMHHVLSYRGSTLTFLRGEGGVQFCVAASTEWKESHQYW GGDDCVVIQLLPNYQIIQK------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------------GAKLLYFNLS IRGYPKGLRAGQDQRAPCLQVDDGFNLVTFCGIPYRINSVEVWGCGSQRD RxxGRVGIL----------------------------------------- -------------------------------------xxxxxAGxxxxxx xx------------------------------------------------ -------------------------------------------------- -x >Tdi 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---------------------------------------------FHRKN CLPVQYLSNWVSSHCPRLVVGLHRYVVHALTTTYRTLGKDQTxxxxVGLD LSTPVLEREPSFENDDNVMLPLSEVWLLATSLPLLFTKPSEHHSPDNLAA GLTSHNFVTKLLGSICPSHWTLLYNSNDHGLGANR--------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------FMHHVLSYRGSTLTFLRGEGGVQFCVAASTEWKESHQYW GGDDCVVIQLLPNYQIIQK------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------------GAKLLYFNLS IRGYPKGLRAGQDQRAPCLQVDDGFNLVTFCGIPYRINSVEVWGCGSQRD R------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -- >Tce M------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------xxxF------------------ ---KGHYKFGTMLFLxxxKxxxxKxxxxxx---xxACDPFLKCKLAFCKT IADECQPFLQRFQTSKPMTxxLFEAVEKLLRYLMNRCxxxDLMKCTGPKx LSIDTKKSENLILSKNIDVGFATKRxxxxxxxxxTERQxxxFIQxxxxML TTMIAKLQERNLFKQKAxRGLFxxxxxVxxxxxxxxxxxxxxxENAKKEY LHxxxxxxxxxxxxxxxxxxxxxxxxxxxxxVxxDARxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxIxxxxxxxxxxxxxxxxxxxx RxxxxxxxxxxxxxxxYVRLxxxLHxxSAAxKQGIGKxxxxxxxxHxxxx xxxxxLGKTTPSSPDRDSNLxxxVxxxxAQHDKRLANYATxxxxxMYAEG DEITREQFNELLLAAYRLAMDFxxDxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxVFxxxxxxxxxxxxxxxxxxxxxxxxxxVGLD LSTPVLEREPSFENDDNVMLPLSEVWLLATSLPLLFTKPSEHHSPDNLAA GLTSHNFVTKLLGSICPSHWTLLYNSNDHGLGANR--------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------FMHHVLSYRGSTLTFLRGEGGVQFCVAASTEWKESHQYW GGDDCVVIQLLPNYQIIQK------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------------GAKLLYFNLS IRGYPKGLRAGQDQRAPCLQVDEGFNLVTFCGIPYRINSVEVWGCGSQRD R------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -- >Tpa -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------------------------------------------GLD LSTPVLEREPSFENDDNVMLPLSEVWLLATSLPLLFTKPSEHHSPDNLAA GLTSHNFVTKLLGSICPSHWTLLYNSNDHGLGANR--------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------FVHNSL--------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -x >Tbi xxx----------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ---------------xxxxxxxxxxxxTxxxxxxxxxx----------xx xxxxxxxxxxxxxxxxxxx----xxxxxxxxxxLKREFQERxxxxxxxx- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------------------KGLD LSTPVLEREPSFENDDNVMLPLSEVWLLATSLPLLFTKPSEHHSPDNLAA GLTSHNFVTKLLGSICPSHWTLLYNSNDHGLGANSVLSKQFLLQYHQEAL EKLKLSxxxxxxxRWASGLLVIGLELSRDQISALLAFYSERVNPHVILYR GYKHLRHPISNTYKSAYTLTPFYREASAVYGSSAHINTSRFAVHVRRENK NxxAECYVIWLAFPEWWALRRRYNSEKEVLCAIx---------------- -----------FMHHVLSYRGSTLTFLRGEGGVQFCVAASTEWKESHQYW GGDDCVVIQLLPNYQIIQRVIHIFYKRRNSQKGCLPHLYRRGPLSPARET PQSPPQGSPPTPPCGPKLRAAFVEPLNPASGTPEVGMSGRTCEAAKAIPT GTLRKDQRGTDDKITVKKASKSLTKPSSKDPPTQSLQDKSKPLLKREVQE RLLKARGPKKVFDMVGIVLPKAIPTTPGRVSPWKIPLPRCHFDLAKFPKA TTPYIIYERTLNELLATRFQSFKRIYTDGSKCGASLGSTFVVEGSNFKFD FPVAVQTNNSEAARHYGVTEVNVRCWRKDLLKLQNCNLTxGAKLLYFNLS IRGYPKGLRAGQDQRAPCLQVDEGFNLVTFCGIPYRINSVEVWGCGSQRD RWYGRVGIL----------------------------------------- -------------------------------------xxxxxxxxxxxxx xx------------------------------------------------ ------------------xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xx >Tte x------------------------------------------------- ---------------------------------xxxxxxxxxxxxxTAHx Lxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxx-------------------------------- -------------------------------xxxxxx------------- --------------------------xxxx-------------------- --------------------------------------xxNVNKGKxxxA GAGSFxxKGKGLPRKSARGVFVIARDVASDRARYLWSFFDVEVKRLxxxx xxxxxxxxxxxxxxxxxxxxxINxxAKSDVSIRKLRDGTxLIQTATDVQS SNIMAITEIPSSNxxxxxxxxxxxxxxxxCKGxxxxFDLDCRxxxxxxxx xxxxxxxxxxxxxxPx---------------------------------- -----------------------------xxxxxxxAD----------KT xxxxxxxxxxxxxxxxxxx----xxxxxxxxxxLKREFQERLGKARGPK- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------------------KGLD LSTPVLEREPSFENDDNVMLPLSEVWLLATSLPLLFTKPSEHHSPDNLAA GLTSHNFVTKLLGSICPSHWTLLYNSNDHGLGANSVLSKQFLLQYHQEAL EKLKLSLLEQCELRWASGLLVIGLELSRDQISALLAFYSERVNPHVILYR GYKHLRHPISNTYKSAYTLTPFYREASAVYGSSAHINTSRFAVHVRRENK NEAAECYVIWLAFPEWWELRRRYNSEKEVLCAIx---------------- -----------FMHHVLSYRGSTLTFLRGEGGVQFCVAASTEWKESHQYW GGDDCVVIQLLPNYQIIQRVIHIFYKRRNSQKGCLPHLYLRGPLSPARET PQSPPQGSPPTPPCGPKLRAAFVEPLNPASGTPEVGMSGRTCEAAKAIPT GTLRKDQRGTDDKITVKKASKTLTKPSSKDPPTQSLQDKSKPLLKREVQE RLLKARGPKKV--------------------------------------- -------------------------------------------------- -AVAVQTNNSEAARHYGVTEVNVRCWRKDLLKLQNCNLTxGAKLLYFNLS IRGYPKGLRAGQDQRAPCLQVDEGFNLVTFCGIPYRINSVEVWGCGSQRD ---------------xxxIPGTTIxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxAAGGLLNMTISQK----------------- -------------------------------------------------- -------------------------------------------------- --