>Tge -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- --------MKVPSI-------------------------------DCTLG GTDNIRGSPTVTVGPDNKVECMLCQCFLEAAEHTTLHMVTHGIGTIVCRC RVCGQQGDLSYFQQTGESE------------------------------- ----------------------------------GFSQKSSLKLHKQSHA GMNPHTCHQCGQKFRFKVSLLSHILSLHGTxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxHxxxxxKDRPYxCExxGRLFSxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxQDHTTQFDPxxxxQxxQTSS-xxxxxVEGTIKDKNTDTELFSPFSHD GxxxxxxxA----------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------------xxxxxxxxLxxxxxxxxxAMPH >Tte M---------------------------------DSLFPHNKCRLCGLVK TEVLDLYSTSARSKGLLSKVNKLLP------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- --------------------------KE---------------------- -------------------------------------------------- -------------------------IVHIVAGDGLPKFVCLDCEMIVNSF AQFSARVQDVQKLxExxxxxFGxVQAYALRSGYLRDTSWRLDKLAELGLE LNNLRSGYLWDTSWRLEKLAELGLELNNLRSGYLWDTSWKLEKLEGIWTV ARCSMSTLIGPVIISKFQEPNPFPPPKYPLGVLxxxxxxxKDNSQLDEIR SNHVNEFVMKVPSI-------------------------------DCTLG GTDNIRGSPTVTVGPDNKVECMLCQCFLEAAEHTTLHMVTHGIGTIVCRC RVCGQQGDLSYFQQTGEx-------------------------------- -----------------------------------FSQKSSLKLHKQSHT GINPHTCHQCGQKFRFKVSLLSHILSLHGTxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxHxxxxxKDRPYxCExxGRLFSxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxQDHTTQFDPxxxxQxxQTSS-xxxxxVEGTIKDKNTDTELFSPFSHD GxxxxxxxA----------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------------xxxxxxxxLxxxxxxxxxAMPH >Tms Mxxxxxxxx---------------xxxxxxxxxxx--------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ------------------------------------------NSQLDGIR SNHVNEFVTKVPSI-------------------------------DCSLR GTDSIRGSPTVTVGPDNKVECMLCQCFIEAAEHTTLHMVTHGIGTIVCRC RVCGQQGDLSYFQQTGESE------------------------------- ----------------------------------GFSQKSSLKLHKQSHA GMNPHTCHQCGQKFRFKVSLLSHILSLHGTxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxHxxxxxKDRPYxCDxxGRLFSxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxQDHTTQFDPxxxxQxxQTSSxxxxxxLEGTIKDKNTDTELFSPFSHD GxxxxxxxA----------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------------xxxxxxxxLxxxxxxxxxAMPH >Tps M---------------------------------DNLFPHNKCRLCGLVK TEVLDLYSTSARSKGLLSKVNKLLP------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- --------------------------KE---------------------- -------------------------------------------------- -------------------------IVHIVAGDGLPKFVCLDCEMIVNSF AQFSARVQDVQKLxExxxxxFG---------------------------- -------------------------------------------------- ----------------------------------------KDNSQLDEIR SNHVNEFVMKDPSI-------------------------------DCTLR GTNSIRGSPTVTVGPDNKVECMLCQCFLEAAEHTTLHMVTHGIGTIVCRC RVCGQQGDLSYFQQTGESEGLIFCHACFLASNKAKRQNNVGHTSNLRLHV CDICSKGFQLRGHLTRHKLIHSGAKPYLCEVCGKGFSQKSSLKLHKQSHA GMNPHTCHQCGQKFRFKVSLLSHILSLHGTxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxHxxxxxKDRPYxCExxGRLFSxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxQDHTTRFDPxxxxQxxQTSS-xxxxxLEGTIKDKNTDTELFSPFSHD GxxxxxxxA----------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------------xxxxxxxxLxxxxxxxxxAMPH >Tdi M---------------------------------DNLFPHNKCRLCGLVK TEVLDLYSTSARSKGLLSKVNKLLP------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- --------------------------KE---------------------- -------------------------------------------------- -------------------------IVHIVAGDGLPKFVCLDCEMIVNSF AQFSARVQDVQKLxExxxxxFG---------------------------- -------------------------------------------------- ----------------------------------------KDNSQLDEIR SNHVNEFVMKDPSI-------------------------------DCTLR GTNSIRESPTVTVGPDNKVECMLCQCFLEAAEHTTLHMVTHGIGTIVCRC RVCGQQGDLSYFQQTGESEGLIFCHACFLASNKAKRQNNVGHTSNLRLHV CDICSKGFQLRGHLTRHKLIHSGAKPYLCEVCGKGFSQKSSLKLHKQSHA GMNPHTCHQCGQKFRFKVSLLSHILSLHGTxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxHxxxxxKDRPYxCExxGRLFSxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxQDHTTRFDPxxxxQxxQTSS-xxxxxLEGTIKDKNTDTELFSPFSHD GxxxxxxxA----------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------------xxxxxxxxLxxxxxxxxxAMPH >Tce -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- --------------------------------------------MIVNSF AQFSVRVQDVQKLxxxxxxxFG---------------------------- -------------------------------------------------- ----------------------------------------KDNSQLDGIR SNHVNEFVTKVPSI-------------------------------DCTLR GTDSIRGSPTVTVGPDNKVECMLCQCFIEAAEHTTLHMVTHGIGTIVCRC RVCGQQGDLSYFQQTGESEGLIFCHACFLASNKAKRQKTVGHTSNLRLHV CDICSKGFQLRGHLTRHKLIHSGAKPYLCEVCGKxFSQKSSLKLHKQSHA GMNPHTCHQCGQKFRFKVSLLSHIxSLHGxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxHxxxxxKDRPYxCDxxGRLFSxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxQDHTTQFDPxxxxQxxQTSxxxxxxxLEGTIKDKNTDTELFSPFSHD Gxxxxxxxx----------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------------xxxxxxxxLxxxxxxxxxAMPH >Tsi x-------xxxxxxxxxxxxxxxxx---------x--------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------------------------------xxxxxxxxxx xxxxxxxxxxxxxxHxxxxxKDRPYxCxxxGRLFSxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxQDHTTQFDPxxxxQxxQTSS-xxxxxLEGTIKDKNTDTELFSPFSHD Gxxxxxxxx----------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------------xxxxxxxxLxxxxxxxxxAMPH >Tpa x------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -----------xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxDCTLG GTDNIRGTPTVTVGPDNKVECMLCQCFLEAAEHTTLHMVTHGIGTIVCRC RVCGQQGDLSYFQQTGESEGLIFCHTCFLASNKAKRQNNVGHTSNLRLHV CNICSKGFQLRGHLTRHKLIHSGAKPYLCEVCGKGFSQKSSLKLHKQSHA GMNPHTCHQCGQKFRFKVSLLSHIxSLHGTxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxHxxxxxKDRPYxCDxxGRLFSxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxQDHTTQFDPxxxxQxxQTSS-xxxxxVEGTIKDKNTDTELFSPFSHD GxxxxxxxxxxxxxxxxxxxxxxxWYS---------------HR------ -------------------------------------------------F LDHQSPxxxxxxxxxxxxxxxxxxxxQALLMLFQEIVRNxxxxxxxxxxx xSTVSQRTY----------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------x---------------------- >Tcm x-------xI---------------------------------------- ------------------------PIYFLYGEASWNVHEDRKFEKEETLV ASINLQCPILTLNLIEIQLPLVPFGPTQVYYIPGTLPRWALHSTWDFTPE SAKCPAEVGIPIYTTWGGALSESIGVDIVDSKWSKISGRAPLQVAGRGMP TPTGALADLGTIDPECDGTPSxxxxxxxxxxxxxxxxxxxxxxxKWSKIS GRAPLQVAGRGxxxxTGALADLGTIDPECDGTPSRTGYRGRNISGANQLV VGVALVSLDEKIFLEYVVVKRTVVEEDDEAPKVAVAAIILVIAYLAEDVV LAANVIQDLVEVVNDAFVEVLIKVVASSSFLGGFLTREVHLTARGVPDRG DSEALGKTKGYFSGDGSCDMQCRGVVRCVESGxxxxxxxxxxxxxxxxxx xxTGVTSPARHSAAPAKSPRPEMRNFKEKTNRANTDEKAVASALSAIIDG GPSGKLSVRKAARIHGEDSECDxxxxxxxxxxxxxxxxxxxxxxxxxxxx RGFGFVPNINDExxxxNVGLNxxxxIVHIVAGDGLPKFVCLDCEMIVNSF AQFSARVQDVQKLxExxxxxFG---------------------------- -------------------------------------------------- ----------------------------------------KDNSQLDEIR SNHVDEFVMKVPSI-------------------------------DCTLR GTDSIRGSPTVTVGPDNKVECMLCQCFLEAAEHTTLHMVTHGIGTIVCRC RVCGQQGDLSYFQQTGESEGLIFCHACFLASNKAKRQNNVGHTSNLRLHV CDICSKGFQLRGHLTRHKLIHSGAKPYLCEVCGKGFSQKSSLKLHKQSHA GMNPHTCHQCGQKFRFKVSLLSHIxSLHGTxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxHxxxxxKDRPYxCExxGRLFSxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx -------------------------------------------------- ---------------------xxx-------------------------- -------------------------------------------------- -----xx------------------------------------------- --------xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxQEQKKxxxxxxxxxxxxxxxxxxxxxxSRHSLxxISI LLLAQPxxDLDxxxVKDxxxxxxxxxxxxxxxxxxxxxRLKAFFSDLQTT TNxSAVMDVxxxxxxxxxxxxxxxxxxxxLLLRLKLLLLLVLxxxxxxxx xSLLWxxCxSSSRLDIx---------------------- >Tbi x------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- ----------------xxxxLR---------------------------- -------------------------------------------------- ----------------------------------------PDNSQLDEIR SNHVNEFVMKVPSI-------------------------------DCTLG GTDNIRGSPTVTVGPDNKVECMLCQCFLEAAEHTTLHMVTHGIGTIVCRC RVCGQQGDLSYFQQTGER-------------------------------- -----------------------------------FSQKSSLKLHKQSHT GMNPHTCHQCGQKFRFK--------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------------------------------- -------------------------YSAExxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 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