>Tge
M-------------------------------------------------
--------------------PGSNG------------------------T
TGSPRVPVxVxxxRDRRASSxxxxxxxxxxLxx-----------------
--------------------------------------------------
----------------------------------LSSESVEHIPTRTATV
SASKPAANPLQFIKVGPANLYKAAQEQIKKVEEVKKLKEEVRNEEEDWQS
NLDNWKSSRRKRQEHIIERVVEVKKLELEEHDRNRRRSKTFNEMMEDRNR
AGRKLSLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHI
DKYHYETPNGDERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNMNGNQGNEKLTNNVNAEKLPNGTSATKKIPPPV
APRKESAAKIEERLSALERRRSSIDSDATKKLGLQKVDVLKRRELFEKAS
ESEASKPNRVSGDFSKTKSIKDRLSHLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRLSTGDSSSSQSIQERLSSLEKNVNSD
REISPNKLLSEDFSHSIKDRLSNLDSAINRENGSKLTPDKDPSFQTKLAN
FRNTETNLFEEEMDNRLFFPNTTNPDRLMNPEQEIYQTKRQQFHRSLDNL
DAEISNETQKNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPITSNLAPLLESVVNSIDA
FQHGTQSIHKNRNILESPLEDQDINKDTSKFNSVVDCDASNLPATSKDID
VPSYQKVEDINNFVSSENFPTSPLLPMTSGDGSAITYSVNTSSLLDNYNS
VTTYSSSSLNDTISLVEPVSNGCEVVDISGMGDLSGTMSVETNQLLVEVA
HLPSSPTSSSCEILEKTTLEVDKIEEEPQTPVVDTSEFVFFNDVPNPANV
SQNVLPAFNESIDVSEDSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEVPEKMAAAVAAVCSRDKVSSASAEYFMSKKAHDGNNVRSPQPYI
NVPANFKESAMSLGRKLEQQEDMFISSGRMEHTDGNKSNYVFVEDNLSKE
-----------------------------------------ICDKLDKGI
PSEVQDENKPEPLVVEGGNFISEDIKDSQLFSEQDKVTGNYSNTLIFEKQ
KDDSVSFLNTSNQCNIEKDVIYSIANQIPTLNLSSDIEFIADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDMPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDDGYLEPELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSQHSRQNSELYGNASIT
SEEDEISKREREIIEILEKEEKWRYGSSTTSEQNDIGEKLAAKLRQLEQE
KQRLEWEKVEEEKLLQARQHELQQQEASV---------GSPELTSLQ---
----------SNTIQSGDQLRAERDRLQRENEALERQKEELRLYEQQQQK
QQTKQQHWGSTSALPPLNQRWDSTRLSLQDISHQ----------------
--------------------------------------------------
----------------------------------TGHTIPAPAPVQHLTQ
SPINNYRLSLPNLQQDGGIQTTRVSPSRRAPPPIPPAKPLRVVSQEQSES
IRSSRVPSADHLLSNGSVPSQIGAQTGSQQMSRQTLQALSAAPRSRLIST
DNWMQAKRKPEGQRNNNYQHWLVQEAEHRRITEQQQRAPRRPPPPIQQQV
WNSQLAPRQDKPLPDSIIQTLTQRVQNRVGLVDNKNIP-RR---------
--------------------------------------------------
----------RLEDSPSREAPVQSLPPANNMPQPVAQVDNQEKMLSVSGK
KKCSHCGEELGRGAAMIIESLRLFYHIDCFKCCVCHVQLGDGLMGTDVRV
RNNKLHCHNCYSSDD-----------------------------------
--------------------------------------------------
------------------------------------------xxxxxxxF
xxxxxxxxxxxxxxPxxxxxxxxxxxxxx
>Tbi
M-------------------------------------------------
--------------------PGSNG------------------------T
TGSPRVPVSxxPYRDRRASSxSxxxxxxxxLRQ-----------------
--------------------------------------------------
----------------------------------LSSESVEHIPTRTATV
SASKPAANPLQFIKVGPANLYKAAQEQIKKVEEVKKLKEEVRNEEEDWQS
NLDNWKSSRRKRQEHIIERVVEVKKLELEEHDRNRRRSKTFNEMMEDRNR
AGRKLSLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHL
DKYHYETPNGEERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNMNGNQGNEKLTNNVNAEKLPNGTSATKKIPPPV
APRKESAAKIEERLSALERRRSSIDSDTTKKLGLQKVDVLKRRELFEKAS
ESEASKPNRVSGDFSKTKSIKDRLSHLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRISTGDSSSSQSIQERLSSLEKNVNSD
RELSPNKLLSEDFSHSIKDRLSNLDSAINRENGSKLTPDKDPSFQTKLAN
FRNTETNLFEEEMDNRLFFPNTINPDRLMNPEQEIYQTKRQQFHRSLDNL
DAEISNETQKNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPITSNLAPLLESVANSIDA
FQHETQSIHKNRNILESPLEDQDINKDTSKFNSVVDCDASNLPATSKDID
VPSYQKVEDINNFVSSENFPTSPLLPMTSGDGSAITYSVNTSSLLDNYNS
VTTYSSSSLNDTISLVEPVSNGCEVVDISGMGDLSGTMSVETNQLLVEVA
HLPSSPTSSSCEILEKTTLEADKIKEELQTPVVDTSEFVFSNDVPNPANV
SQNVLPAFNESIDMSEDSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEVPEKMAAAVAAVCSRDKVSSASAEYFMSKKAHDGNNVRSPQPYI
NVPANFKESAMSLGGKLEQQEDMFISSGRMEHTDGNKSSYVFVEDNLSKE
-----------------------------------------ICDKLDKGI
PSEVQDENKPEPLVVEGGNFISEDIKDSQLFSEQDKVTGNYSNTLIFEKQ
KDDSVSFLNTSNQCNIEKDVIYSIANQIPTLNLSSDIEFIADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDMPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDDGYLEPELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSQHSRQNSELYGNASIT
SEEDEISKREREIIEILEKEEKWRYGSSTTSEQNDIGEKLAAKLRQLEQE
KQRLEWEKVEEEKLLQARQHELQQQEASV---------GSPELTSLQ---
----------SNTIHSGDQLRAERDRLQRENEALERQKEELRLYEQQQQK
QQTQQQHWGSTSALPPLNQRWDSTRLSLQDISHQVTDEEVYTHLYGRRVE
NHLGxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx-----------
----------------------------------TGHTIPAPAPVQHLTQ
SPINNYRLSLPNLQQDGGIQTTRVSPSRRAPPPIPPAKPLRVVSQEQNES
IRSSRVPSADHLLSNGSVPSQIGAQTGSQQMSRQTLQALSAAPRSRLIST
DNWMQAKRKPEGQRNNNYQHWLVQEAEHRRITEQQQRAPRRPPPPIQQQV
WNSQLAPRQDKPLPDSIIQTLTQRVQNRVGLVDNKNIP-RR---------
--------------------------------------------------
----------RLEDSPSREAPVQSLPPANNIPQPVAQVDNQEKMLSVSGK
KKCSHCGEELGRGAAMIIESLRLFYHIDCFKCCVCHVQLGDGLMGTDVRV
RNNKLHCHNCYSSDD----------------------------G------
--------------------------------------------------
--------------------------------------------------
-----------------------------
>Tte
M-------------------------------------------------
--------------------PGSNG------------------------T
TGSPRVPVSVAPYRDRRASSSSxxxLPDTNLRxxxxxxxxxxxxxSSSCR
KIMSVDVAKGxxxxxxxxxxxLxSDNSLxxDxxPLxxxx-----------
-----------------------xxxxxxxxxxxLSSESVEHIPTRTATV
SASKPAANPLQFIKVGPANLYKAAQEQIKKVEEVKKLKEEVRNEEEDWQS
NLDNWKSSRRKRQEHIIERVVEVKKLELEEHDRNRRRSKTFNEMMEDRNR
AGRKLSLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHL
DKYHYETPNGEERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNMNGNQGNEKLTNNVNAEKLPNGTSATKKIPPPV
APRKESAAKIEERLSALERRRSSIDSDTTKKLGLQKVDVLKRRELFEKAS
ESEASKPNRVSGDFSKTKSIKDRLSHLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRISTGDSSSSQSIQERLSSLEKNVNSD
RELSPNKLLSEDFSHSIKDRLSNLDSAINRENGSKLTPDKDPSFQTKLAN
FRNTETNLFEEEMDNRLFFPNTINPDRLMNPEQEIYQTKRQQFHRSLDNL
DAEISNETQKNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPITSNLAPLLESVANSIDA
FQHETQSIHKNRNILESPLEDQDINKDTSKFNSVVDCDASNLPATSKDID
VPSYQKVEDINNFVSSENFPTSPLLPMTSGDGSAITYSVNTSSLLDNYNS
VTTYSSSSLNDTISLVEPVSNGCEVVDISGMGDLSGTMSVETNQLLVEVA
HLPSSPTSSSCEILEKTTLEADKIKEELQTPVVDTSEFVFSNDVPNPANV
SQNVLPAFNESIDMSEDSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEVPEKMAAAVAAVCSRDKVSSASAEYFMSKKAHDGNNVRSPQPYI
NVPANFKESAMSLGGKLEQQEDMFISSGRMEHTDGNKSNYVFVEDNLSKE
-----------------------------------------ICDKLDKGI
PSEVQDENKPEPLVVEGGNFISEDIKDSQLFSEQDKVTGNYSNTLIFEKQ
KDDSVSFLNTSNQCNIEKDVIYSIANQIPTLNLSSDIEFIADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDMPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDDGYLEPELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSQHSRQNSELYGNASIT
SEEDEISKREREIIEILEKEEKWRYGSSTTSEQNDIGEKLAAKLRQLEQE
KQRLEWEKVEEEKLLQARQHELQQQEASV---------GSPELTSLQxxx
xxNFYSSxxx-------DQLRAERDRLQRENEALERQKEELRLYEQQQQK
QQTQQQHWGSTSALPPLNQRWDSTRLSLQDISHQVTDEEVYTHLYGRRVE
NHLGKTTLNTPDQDLITNLPVIGSLVYRESGAIDHSTTE-----------
----------------------------------TGHTIPAPAPVQHLTQ
SPINNYRLSLPNLQQDGGIQTTRVSPSRRAPPPIPPAKPLRVVSQEQNES
IRSSRVPSADHLLSNGSVPSQIGAQTGSQQMSRQTLQALSAAPRSRLIST
DNWMQAKRKPEGQRNNNYQHWLVQEAEHRRITEQQQRAPRRPPPPIQQQV
WNSQLAPRQDKPLPDSIIQTLTQRVQNRVGLVDNKNIPxTL---------
--------------------------------------------------
----------RLEDSPSREAPVQSLPPANNIPQPVAQVDNQEKMLSVSGK
KKCSHCGEELGRGAAMIIESLRLFYHIDCFKCCVCHVQLGDGLMGTDVRV
RNNKLHCHNCYSSDD----------------------------DLxxxxx
xxxxxxGxxxxxxxxxA----TxxxxxTxITTQxxxxxNxxxxxxxWVTx
xxxIxDNDKAIxxSYxxxxxxxxxxCxxxxxxxxxxxxxxxxx-------
----------------------------x
>Tpa
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-------------------------------------------MMEDRNR
AGRKLSLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHL
DKYHYETPNGDERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNMNGNQGNEKLTNNVNAEKLPNGTSATKKIPPPV
APRKESAAKIEERLSALERRRSSIDSDATKKLGLQKVDVLKRRELFEKAS
ESEASKPNRVSGDFSKTKSIKDKFSHLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRLSTGDSSSSQSIQERLSSLEKNVNSD
RELSPNKLLSEDFSHSIKDRLSNLDSAINRENGSKLTPDKDPSFQTKLAN
FRNTETNLFEEEMDNRLFFPNTINPDRLMNPEQEIYQTKRQQFHRSLDNL
DAEISNETQKNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPITSNLAPLLESVANSIDA
FQHETQSIHKNKNILESPLEDQDINKDTSKFNSVVDCDASNLPATSKDID
VPSYQKVEDINNFVSSENFPTSPLLPMTSGDGSAITYSVNTSSLLDNYNS
VTTYSSSSLNDTISLVEPVSNGCEVVDISGMGDLSGTMSVETNQLFVEVA
HLPSSPTSSSCEILEKTTLEADKIEEELQTPVVDTSEFVFSNDVPNPAIV
SQNVLPAFNESIDVSEDSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEVPEKMAAAVATVCSRDKVSSASAEYFMSKKAHDGNNVRSPQPYI
NVPANFKESAMSLGGKLEQQEDMFISSGRMEHTDGNKSNYVFVEDNLSKE
-----------------------------------------ICDKLDKGI
PSEVQDENKPEPLVVEGGNFISEDIKDSQLFSEQDKVTGNYSNTLIFEKQ
KDDSVSFLNTSNQSNIEKDVIYSIANQIPTLNLSSDIEFIADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDMPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDDGYLEPELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSQHSRQNSELYGNASIT
SEEDEISKREREIIEILEKEEKWRYGSSTTSEQNDIGEKLAAKLRQLEQE
KQRLEWEKVEEEKLLQARQHELQQQEASV---------GSPELTSLQ---
----------SNTIQSGDQLRAERDRLQRENEALERQKEELRLYEQQQQK
QQTKQQHWGSTSALPPLNQRWDSTR-------------------------
----xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx--------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
----------------xxxxxxx---------------------------
--------------------------------------------------
-----------------------------
>Tms
M----------------------------xxxxxxxxxxxxxxxxxxxxx
xxxxAxxxxxxxxxxxxxxxx-----------------------------
--------------------------------x-----------------
--------------------------------------------------
--------------------------------xxLSSESIEHIPTRTATM
SASKPAANPLQFIKVGPANLYKAAQEQIKKVEEVKKLKEEVRNEEEDWQS
NLDNWKSSRRKRQEHIIERVVEVKKLELEEHDRNRRRSKTFNEMMEDRNR
AGRKLGLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHL
DKYNYETPNGDERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNVNGNQGNEKLTNNVSGENLSNGTSATKKIPPPV
APRKESAAKIEERLLAREQRRSSIDSDTTKKLGLQKVDVLKRRELFEKAS
ESEASKPNRVYGDFSKTKSIKERLSNLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRLSTGDSSSSQSIQERLSSLEKNVNND
RELSPNKLLSEDFSHSIKDRLSNLDSAMNRENESKLTPDKDPSFQTKLAN
FRNTETNPFEEGMDTRLFFPNTLNPDRLMNPEEEIYQPKRQQFHRSLDNL
DAEISSETQRNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPVTSNLAPLLESVVNSIDA
FQHGTQSIHKNRNILENTLEDQDINKDTSKFNSVVDCDASTLPATSKDID
VPSYQKVEDIINFVSFETLPTSPLLPMTSGDGSAITYSENTSSLLDNYNS
VTTYSSSSLNDTISLVEPASNGCEVVDISGMGDLSGTISVETNQLLVEVA
HLPSSPTSSPCEILEKTTLEADKIKEELQTPMVDTSEFVFPNDVPNPTNV
SQNVLPAFNESIDMSEDSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEAPEKMAAAMAAVCSRDKVSNGSPEYFMSKKAHDGNNVKSPQPYI
NVPANFKESAMSLGGKLEQQEDMFISCGRMEHTDGNKSNYVFVEDNLSKE
-----------------------------------------ICDRLEKGV
PSEVQDENKPKLLVVEGGNFISEDIKDSQLFSEQDKVTDNHSNTLIFEKQ
KDDSVSFLNTPNQCNIEEGVIHSIANQIPTLNLLSDIEFIADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDVPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDDGYLEPELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSQHSRQNSELYGNASIT
SEEDEISKREREIIEILEKEEKWRYGDSTTSEQNDIGEKLAAKLRQLEQE
KQRLEWEKVEEEKLLQARQHELQHQEVTLPTLADLQVxGSPELTSLQ---
----------SNTIQTGEQLRAERDRLQRENEALERQKEELRLYEQQQQK
QQTQQQHWGSTSALPALNQRWDSTRLSLQDISHQ----------------
--------------------------------------------------
----------------------------------TGHTIPAPAPVQHLTQ
SPINNYRLSLPNLQQDGGIQTTRVSPSRRAPPPIPPAKPLRVVSQEQRES
IRSSRVPSADHLLSNGSVPSQIGAQTGSQQMSRQTLQALSAAPRSRLIST
DNWMQAKRKPEGQRNNNYQHWLVQEAEHRRITEQQQRAPRRPPPPAQQQV
WNSQLAPRQDKPLPDSIIQTLTQRVQNRVGLVDNKNIP-RRxxIEVEEVN
PHLCVGRVENYLGKTTPGSPDRDLNLDLPVLSSLAQHETGALANYAEAHV
HLLIWSKATLELEDSPSREAPVQSLPPANNIPQPVAQVDNQEKMLSVSGK
KKCSHCGEELGRGAAMIIESLRLFYHIDCFKCCVCHVQLGDGLMGTDVRV
RNNKLHCHNCYSSDD----------------------------Gx-----
--------------------------------------------------
-----------------------------xxxx-----------------
----------------------------x
>Tsi
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
-----------------------------------------------RNR
AGRKLGLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHL
GKYNYETPNGDERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNVNGNQGNEKLTNNVSAENLSNGTSATKKIPPPV
APRKESAAKKEERLSAREQRRSSIDSDTTKKLGLQKVDVLKRRELFEKAS
ESEASKPNRAYGDFSKTKSIKERLSNLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRLSTGDSASSQSIQERLSSLEKNVNND
RELSPNKLLSEDFSHSIKDRLSNLDSAMNRENGSKLTPDKDPSFQTKLAN
FRNTETNPFEEGMNNRLFFPNTLNPDRLMNPEEEIYQTKRQQFHRSLDNL
DAEISSETQRNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPVTSNLAPLLESVVNSIDA
LQHGTQSIHKNRDILENTLEDQDINKDTCKFNSVVDCDASNLPATSKDID
VPSYQKVEDIINFVSFETFPTSPLLPMTSGDGSAITYSENTSSLLDNYNS
VTTYSSSSLNDTISLVEPASNGCEVVDISGVGDLSGTMSVETNQLLVEVA
HLPSSPTSSPCEILEKTTLEADKIKEELQTPTVDTPEFVFPNYVPNPANV
SQKVLPAFNESIDMSEDSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEAPEKMAAAMAAVCSRDKVSSASEEYFMSEKAHDGNNVKSLQPNI
NVPANFKESAMSLGGKLEQQEDMFISSGRMEHTDENKSNYVFVEDNLSKE
-----------------------------------------ICDRLEKGV
PSQVQDENKSKLLAVEGGNFISEDIKDHQLFSEQDKVTDNHSNTLIFEKQ
KDDSVSFLNTSNQCNIEEDVIYSIANQIPTLNLLSDIEFVADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDVPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDDGYLEPELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSLHSRQNSE--------
-------------------------------------------xRQLEQE
KQRLEWEKVEEEKLLQARQHELQHQEASV---------GSPELTSLQ---
----------SNTIQTGEQLRAERDRLQRENEALERQKEELRLYEQQQQK
QQTQQQHWGSTSALPALDQRWDSTRLSLQDISHQ----------------
--------------------------------------------------
----------------------------------TGHTIPAPAPVQHLTQ
SPINNYRLSLPNLQQDGGIQTTRVSPSRRAPPPIPPAKPLRVVSQEQRES
IRSSRVPSADHLLSNGSVPSQIGAQTNSQQMSRQTLQALSAAPRSRLIST
DNWMQAKRKPEGQRNNNYQHWLVQEAEHRRITEQQQRAPRRPPPPAQQQV
WNSQLAPRQDKPLPDSIIQTLTQRVQNRVGLVDNKNIP-RR---------
--------------------------------------------------
----------RLEDSPSREAPVQSLPPANNIPQPVAQVDNQEKMLSVSGK
KKCSHCGEELGRGAAMIIESLRLFYHIDCFKCCVCHVQLGDGLMGTDVRV
RNNKLHCHNCYSSDD----------------------------Gx-----
--------------------------------------------------
-----------------------------xxxx-----------------
----------------------------x
>Tps
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx--------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
----------------------------------LSSESVEHIPTRTATV
SASKPAANPLQFIKVGPANLYKAAQEQIKKVEEVKKLKEEVRNEEEDWQS
NLDNWKSSRRKRQEHIIERVVEVKKLELEEHDRNRRRSKTFNEMMEDRNR
AGRKLGLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHL
GKYNYETPNGDERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNVNGNQGNEKLTNNVSAENLSNGTSATKKIPPPV
APRKESAAKKEERLSAREQRRSSIDSDTTKKLGLQKVDVLKRRELFEKAS
ES--SKPNRAYGDFSKTKSIKERLSNLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRLSTGDSASSQSIQERLSSLEKNLNND
RELSPNKLLSEDFSHSIKDRLSNLDSAMNRENGSKLTPDKDPSFQTKLAN
FRNTETNPFEEGMNTRLFFPNTLNPDRLMNPEEEIYQTKRQQFHRSLDNL
DAEISSETQRNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPVTSNLAPLLESVVNSIDA
LQHGTQSIHKNRNILENTLEDQDINKDTSKFNSVVDCDASILPATSKDID
VPSYQNVEDTINFVSFETFPTSPLLPIISGDGSAITYSENTSSLLDNYNS
VTTYSSSSLNDTISLVEPASNGCEVVDISRMGDLSGTMSVETNQLLVEVA
HLPSSPTSSPSEISEKTTLDADKIKEELKTPMVDTSEFVFPNDVPNPSNV
SQKVLPAFNESIDMSENSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEAPEKMAAAMAAVCSRDKVSSASAEYFMSEKAHDGNNVKSLQPYI
NVPANFKESAMSLGGKLEQQEDMFISSGRMEHTDGNKSNYVFVEDNLSKE
-----------------------------------------ICDRLEKEV
PSQVQDENKSKLLAVEGGNFISEDIKDYQLFSEQDKVTDNHSNTLIFEKQ
KDDSVSFLNTSNQCNIEEDVIYSIANQIPTLNLLSDIEFVADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDVPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDDGYLEPELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSQHSRQNSELYGNASIT
SEEDEISKREREIIEILEKEEKWRYGDNTTSEQNDIGEKLAAKLRQLEQE
KQRLEWEKVEEEKLLQARQHELQHQEASV---------GSPELTSLQ---
----------SNTIQTGEQLRAERDRLQRENEALERQKEELRLYEQQQQK
QQTQQQHWGSTSALTALNQRWDSTRLSLQDISHQ----------------
--------------------------------------------------
----------------------------------TGHTIPAPAPVQHLTQ
SPVNNYRLSLPNLQQDGGIQTTRVSPSRRAPPPIPPAKPLRVVSQEQRES
IRSSRVPSADNLLSNGSVPSQIGAQTNSQQMSRQTLQALSAAPRSRLIST
DNWMQAKRKPEGQRNNNYQHWLVQEAEHRRITEQQQRAPRRPPPPAQQQV
WNSQLAPRQDKPLPDSIIQTLTQRVQNRVGLVDNKNIP-RR---------
--------------------------------------------------
----------RLEDSPSREAPVQSLPPANNIPQPVAQVDNQEKMLSVSGK
KKCSHCGEELGRGAAMIIESLRLFYHIDCFKCCVCHVQLGDGLMGTDVRV
RNNKLHCHNCYSSDD----------------------------G------
--------------------------------------------------
--------------------------------------------------
-----------------------------
>Tce
M-------------------------------------------------
--------------------xxxxx------------------------x
xGSPRVPVxxxxxRDRRAxxxxxxxxxxxxLRQ-----------------
--------------------------------------------------
----------------------------------LSSESVEHIPTRTATV
SASKPAANPLQFIKVGPANLYKAAQEQIKKVEEVKKLKEEVRNEEEDWQS
NLDNWKSSRRKRQEHIIERVVEVKKLELEEHDRNRRRSKTFNEMMEDRNR
AGRKLGLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHL
DKYNYETPNGDERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNVNGNQGNEKLTNNVSGENLSNGTSATKKIPPPV
APRKESAAKIEERLLAREQRRSSIDSDTTKKLGLQKVDVLKRRELFEKAS
ESEASKPNRVYGDFSKTKSIKERLSNLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRLSTGDSSSSQSIQERLSSLEKNVNND
RELSPNKLLSEDFSHSIKDRLSNLDSAMNRENGSKLTPDKDPSFQTKLAN
FRNTETNPFEEGMDTRLFFPNTLNPDRLMNPEEEIYQPKRQQFHRSLDNL
DAEISSETQRNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPVTSNLAPLLESVVNSIDA
FQHGTQSIHKNRNILENTLEDQDINKDTSKFNSVVDCDASTLPATSKDID
VPSYQKVEDIINFVSFETLPTSPLLPMTSGDGSAITYSENTSSLLDNYNS
VMTYSSSSLNDTISLVEPASNGCEVVDISGMGDLSGTISVETNQLLVEVA
HLPSSPTSSPCEILEKTTLEADKIKEELQTPMVDTSEFVFPNDVPNPTNV
SQNVLPAFNESIDMSEDSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEAPEKMAAAMAAVCSRDKVSNGSAEYFMSKKAHDGNNVKSPQPYI
NVPANFKESAMSLGGKLEQQEDMFISSGRMEHTDGNKSNYVFVEDNLSKE
-----------------------------------------ICDRLEKGV
PSEVQDENKPKLLVVEGGNFISEDIKDSQLFSEQDKVTDNHSNTLIFEKQ
KDDSVSFLNTPKQCNIEEDVIHSIANQIPTLNLLSDIEFIADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDVPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDD-----ELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSQHSRQNSELYGNASIT
SEEDEISKREREIIEILEKEEKWRYGDSTTSEQNDI-------------E
KQRLEWEKVEEEKLLQARQHELQHQEASV---------GSPELTSLQ---
----------SNTIQTGEQLRAERERLQRENEALERQKEELRLYEQQQQK
QQTQQQHWGSTSALPALNQRWDSTRLSLQDISHQ----------------
--------------------------------------------------
----------------------------------TGHTIPAPAPVQHLTQ
SPINNYRLSLPNLQQDGGIQTTRVSPSRRAPPPIPPAKPLRVVSQEQRES
IRSSRVPSADHLLSNGSVPSQIGAQTGSQQMSRQTLQALSAAPRSRLIST
DNWMQAKRKPEGQRNNNYQHWLVQEAEHRRITEQQQRAPRRPPPPAQQQV
WNSQLAPRQDKPLPDSIIQTLTQRVQNRVGLVDNKNIP-RR---------
--------------------------------------------------
----------RLEDSPSREAPVQSLPPANNIPQPVAQVDNQEKMLSVSGK
KKCSHCGEELGRGAAMIIESLRLFYHIDCFKCCVCHVQLGDGLMGTDVRV
RNNKLHCHNCYSSDD----------------------------G------
--------------------------------------------------
--------------------------------------------------
-----------------------------
>Tdi
x-------------------------------------------------
------------------------xxxxxxxxxxxxxxxxxxxxxxxxxx
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------------------
NLDNWKSSRRKRQEHIIERVVEVKKLELEEHDRNRRRSKTFNEMMEDRNR
AGRKLGLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHL
GKYNYETPNGDERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNVNGNQGNEKLTNNVSAENLSNGTSATKKIPPPV
APRKESAAKKEERLSAREQRRSSIDSDTTKKLGLQKVDVLKRRELFEKAS
ES--SKPNRAYGDFSKTKSIKERLSNLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRLSTGDSASSQSIQERLSSLEKNLNND
RELSPNKLLSEDFSHSIKDRLSNLDSAMNRENGSKLTPDKDPSFQTKLAN
FRNTETNPFEEGMNTRLFFPNTLNPDRLMNPEEEIYQTKRQQFHRSLDNL
DAEISSETQRNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPVTSNLAPLLESVVNSIDA
LQHGTQSIHKNRNILENTLEDQDINKDTSKFNSVVDCDASILPATSKDID
VPSYQNVEDTINFVSFETFPTSPLLPIISGDGSAITYSENTSSLLDNYNS
VTTYSSSSLNDTISLVEPASNGCEVVDISRMGDLSGTMSVETNQLLVEVA
HLPSSPTSSPSEISEKTTLEADKIKEELKTPMVDTSEFVFPNDVPNPSNV
SQKVLPAFNESIDMSEDSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEAPEKMAAAMAAVCSRDKVSSASAEYFMSEKAHDGNNVKSLQPYI
NVPANFKESAMSLGGKLEQQEDMFISSGRMEHTDENKSNYVFVEDNLSKE
-----------------------------------------ICDRLEKEV
PSQVQDENKSKLLAVEGGNFISEDIKDYQLFSEQDKVTDNHSNTLIFEKQ
KDDSVSFLNTSNQCNIEEDVIYSIANQIPMLNLLSDIEFVADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDVPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDDGYLEPELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSQHSRQNSELYGNASIT
SEEDEISKREREIIEILEKEEKWRYGDSTTSEQNDI-------------E
KQRLEWEKVEEEKLLQARQHELQHQEASV---------GSPELTSLQ---
----------SNTIQTGEQLRAERDRLQRENEALERQKEELRLYEQQQQK
QQTQQQHWGSTSALPALNQRWDSTRLSLQDISHQV---------------
--------------------------------------ELEEVNPHLRGG
RVENHLGKTTLSSPDRDSNLDLPVLGGRAQHxxxTGHTIPAPAPVQHLTQ
SPVNNYRLSLPNLQQDGGIQTTRVSPSRRAPPPIPPAKPLRVVSQEQRES
IRSSRVPSADHLLSNGSVPSQIGAQTNSQQMSRQTLQALSAAPRSRLIST
DNWMQAKRKPEGQRNNNYQHWLVQEAEHRRITEQQQRAPRRPPPPAQQQV
WNSQLAPRQDKPLPDSIIQTLTQRVQNRVGLVDNKNIP-RR---------
--------------------------------------------------
----------RLEDSPSREAPVQSLPPANNIPQPVAQVDNQEKMLSVSGK
KKCSHCGEELGRGAAMIIESLRLFYHIDCFKCCVCHVQLGDGLMGTDVRV
RNNKLHCHNCYSSDDxxxxxxxxxxxxxxDRxxxxxxxxxxxxx------
--------------------------------------------------
--------------------------------------------------
-----------------------------
>Tcm
M-------------------------------------------------
--------------------------------------------------
--------------------------------------------------
--------------------------------------xxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxx----------LSSESVEHIPTRTATV
SASKPAANPLQFIKVGPANLYKAAQEQIKKVEEVKKLKEEVRNEEEDWQS
NLDNWKSSRRKRQEHIIERVVEVKKLELEEHDRNRRRSKTFNEMMEDRNR
AGRKLGLQVFKDEDANDLSDLGIGTSSGKSSISEDYNHDDNLSVDGREHL
GKYNYETPNGDERKNGLNGHHDDDTSTTATISSPEPEEYTYERAIQSYVN
FTETRVKSRTMNNINNNVNGNQGNEKLTNNVSADILSNGTSATKKIPPPV
APRKESAAKKEERLSAREQRRSSIDSDTTKKLGLQKVDVLKRRELFEKAS
ESEASKPNRAYGDFSKTKSIKERLSNLEKHNEDANGNKRRHSTDVSSSVK
DRLSQFKKSSENISLKESPKLIHRLSTGDSASSQSIQERLSSLEKNVNND
RELSPNKLLSEDFSHSIKDRLSNLDSAMNRENGSKLTPDKDPSFQTKLAN
FRNTETNPFEEGMNTRLFFPNTLNPDRLMNPEEEVYQTKRQQFHRSLDNL
DAEISSETQRNDTSFERVQSLEDLECCSNTRNYPPSSSSTEMLALSTQSG
DTDREDSGIHTADVSCSVSQADEPVEDSEIVPVTSNLAPLLESVVNSIDA
LQHGTQSIHKNRDILENTLEDQDINKDTCKFNSVVDCDASNLPATSKDID
VPSYQKVEDIINFVSFETFPTSPLLPMTSGDGSAITYSENTSSLLDNYNS
VTTYSSSYLNDTISLVEPASNGCEVVDISGVGDLSGTMSVETNQLLVEVA
HLPSSPTSSPCEILEKTTLEADKIKEELQTPTVDTPEFVFPNYVPNPANV
SQKVLPAFNESIDMSEDSFETSKTLSFDEFQPESVGSTDFESCRSNASSP
ESLPMEAPEKMAAAMAAVCSRDKVSSASAEYFMSEKAHDGNNVKSLQPYI
NVPANFKESAMSLGGKLEQQEDMFISSGRMEHTNENKSNYVFVEDNLSKE
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx---------
--------------------------------------------------
---------------------------IPTLNLLSDIEFVADLAFPLGPP
TSAEPPKEKPPPPPTDLSDEDVPPPVTSLKRLDSTKRIKKEIRKKRSDFL
GIEGGNDDGYLEPELKLAPPPDMVMFLVEERRSEQQMYRQSICSESDSAL
GETTESRDSGVELDRGHPDDMWTTSQPAFSPSSSLHSRQNSELYGNASIT
SEEDEISKREREIIEILEKEEKWRYGDSTTSEQNDI-------------E
KQRLEWEKVEEEKLLQARQHELQHQEVTLPTLADLQVxGSPELTSLQ---
----------SNTIQTGEQLRAERDRLQRENEALERQKEELRLYEQQQQK
QQTQQQHWGSTSALPALDQRWDSTRLSLQDISHQ----------------
--------------------------------------------------
----------------------------------TGHTIPAPAPVQHLTQ
SPINNYRLSLPNLRQDGGIQTTRVSPSRRAPPPIPPAKPLRVVSQEQRES
IRSSRVPSADHLLSNGSVPSQIGAQTNSQQMSRQTLQALSAAPRSRLIST
DNWMQAKRKPEGQRNNNYQHWLVQEAEHRRITEQQQRAPRRPPPPAQQQV
WNSQLAPRQDKPLPDSIIQTLTQRVQNRVGLVDNKNIP-RR---------
--------------------------------------------------
----------RLEDSPSREAPVQSLPPANNIPQPVAQVDNQEKMLSVSGK
KKCSHCGEELGRGAAMIIESLRLFYHIDCFKCCVCHVQLGDGLMGTDVRV
RNNKLHCHNCYSSDD----------------------------Gx-----
--------------------------------------------------
-----------------------------xxxx-----------------
----------------------------x